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T78811PROTAC AR-NTD degrader 1；化合物 PROTAC AR-NTD degrader 1PROTAC AR-NTD degrader 1
PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal domain (AR-NTD) of the Androgen Receptor variant AR-V7. By antagonizing AR-NTD, this compound effectively degrades AR-V7 protein and triggers apoptosis in prostate cancer (PC) cells, with degradation efficiencies in VCaP cells recorded at 62.2% (1 μM) and 71.1% (5 μM), as noted in reference [1].
价 格：￥电议型 号：T78811产 地：中国大陆
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T78782PROTAC BTK Degrader-6；化合物 PROTAC BTK Degrader-6PROTAC BTK Degrader-6
PROTAC BTK Degrader-6 (Compound 15), with a DC50 of 3.18 nM, exhibits anti-inflammatory properties by inhibiting NF-κB activation and suppressing the expression of pro-inflammatory cytokines, such as IL-1β and IL-6 [1].
价 格：￥电议型 号：T78782产 地：中国大陆
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T78647PROTAC BRD4 Degrader-16；化合物 PROTAC BRD4 Degrader-16PROTAC BRD4 Degrader-16
PROTAC BRD4 Degrader-16 is a potent degrader of BRD4, exhibiting IC50 values of 34.58 nM for BRD4 (BD1) and 40.23 nM for BRD4 (BD2). It significantly reduces Cyclin B1 expression, thereby impeding G2/M phase progression, and induces apoptosis in MV-4-11 cells [1].
价 格：￥电议型 号：T78647产 地：中国大陆
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T78629PROTAC α-synuclein degrader 3；化合物 PROTAC α-synuclein degrader 3PROTAC α-synuclein degrader 3
PROTAC α-synuclein degrader 3 (compound 5) serves as a potent and selective agent for degrading α-synuclein and is utilized in Parkinson´s disease research [1].
价 格：￥电议型 号：T78629产 地：中国大陆
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T77976PROTAC Her3 Degrader-8；化合物 PROTAC Her3 Degrader-8PROTAC Her3 Degrader-8
PROTAC Her3 Degrader-8 (Compound PP2) is a proteolysis targeting chimera (PROTAC) capable of degrading the Her3 protein in vitro and within cellular assays, with potential to investigate diseases modulated by HER family proteins [1].
价 格：￥电议型 号：T77976产 地：中国大陆
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T77975PROTAC BRD9 Degrader-6；化合物 PROTAC BRD9 Degrader-6PROTAC BRD9 Degrader-6
PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].
价 格：￥电议型 号：T77975产 地：中国大陆
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T77974PROTAC BCR-ABL Degrader-1；化合物 PROTAC BCR-ABL Degrader-1PROTAC BCR-ABL Degrader-1
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and demonstrates antiproliferative effects on K562 cells, suggesting its utility in cancer research [1].
价 格：￥电议型 号：T77974产 地：中国大陆
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T77936PROTAC BRD9 Degrader-4；化合物 PROTAC BRD9 Degrader-4PROTAC BRD9 Degrader-4
PROTAC BRD9 Degrader-4 is a bifunctional degrader targeting BRD9, designed for cancer research applications.
价 格：￥电议型 号：T77936产 地：中国大陆
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T77931PROTAC IRAK3 degrade-1 formic；化合物 PROTAC IRAK3 degrade-1 formicPROTAC IRAK3 degrade-1 formic
PROTAC IRAK3 Degrade-1 (Compound 23) is a selective and potent IRAK3 degrader, demonstrating an IC50 value of 5 nM [1].
价 格：￥电议型 号：T77931产 地：中国大陆
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T77928PROTAC PTK6 ligand-1；化合物 PROTAC PTK6 ligand-1PROTAC PTK6 ligand-1
PROTAC PTK6 ligand-1 serves as an intermediate in the synthesis of BTK kinase inhibitors [1] and is utilized in the preparation of ARD-61 [2].
价 格：￥电议型 号：T77928产 地：中国大陆
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T77926PROTAC KRAS G12C degrader-1；化合物 PROTAC KRAS G12C degrader-1PROTAC KRAS G12C degrader-1
PROTAC KRAS G12C degrader-1, a cereblon-based degrader, promotes CRBN/KRAS G12C dimerization and facilitates the degradation of GFP-KRAS G12C in reporter cells [1].
价 格：￥电议型 号：T77926产 地：中国大陆
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T77921PROTAC BRD4 ligand-2 hydrochloride；化合物 PROTAC BRD4 ligand-2 hydrochloridePROTAC BRD4 ligand-2 hydroc
PROTAC BRD4 Ligand-2 Hydrochloride serves as a ligand targeting the BRD4 protein, specifically designed for use with PROTAC CFT-2718.
价 格：￥电议型 号：T77921产 地：中国大陆
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T7701Boc-NH-PEG32-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇PROTAC Linker 10|||2-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇
Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative containing a hydroxyl group and Boc-protected amino group, and is a PROTAC linker.
价 格：￥电议型 号：T7701产 地：中国大陆
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T75171BacPROTAC-1；化合物 BacPROTAC-1BacPROTAC-1
BacPROTAC-1, a potent mSA BacPROTAC degrader, exhibits high affinity for both mSA and the N-terminal domain (NTD) of ClpC, with dissociation constants (K D) of 3.9 μM and 2.8 μM, respectively [1].
价 格：￥电议型 号：T75171产 地：中国大陆
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T75168Homo-BacPROTAC7；化合物 Homo-BacPROTAC7Homo-BacPROTAC7
Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].
价 格：￥电议型 号：T75168产 地：中国大陆
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T75167Homo-BacPROTAC6；化合物 Homo-BacPROTAC6Homo-BacPROTAC6
Homo-BacPROTAC6, a ClpC1 NTD BacPROTAC degrader, effectively targets ClpC2, while Homo-BacPROTAC7 has been shown to efficiently kill M. tuberculosis [1].
价 格：￥电议型 号：T75167产 地：中国大陆
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T75149PROTAC BRD4 Degrader-19；化合物 PROTAC BRD4 Degrader-19PROTAC BRD4 Degrader-19
PROTAC BRD4 Degrader-19 (compound 176) is a proteolysis-targeting chimera (PROTAC) designed to specifically degrade the BRD4 protein, offering potential utility in cancer research [1].
价 格：￥电议型 号：T75149产 地：中国大陆
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T75099PROTAC STAT3 degrader-2；化合物 PROTAC STAT3 degrader-2PROTAC STAT3 degrader-2
PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC 50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research [1] .
价 格：￥电议型 号：T75099产 地：中国大陆
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T75026PROTAC TYK2 degradation agent1；化合物 PROTAC TYK2 degradation agent1PROTAC TYK2 degradation agent1
PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1].
价 格：￥电议型 号：T75026产 地：中国大陆
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T75020PROTAC SOS1 degrader-3；化合物 PROTAC SOS1 degrader-3PROTAC SOS1 degrader-3
PROTAC SOS1 Degrader-3 is a potent agent specifically designed to target and degrade SOS1 via the ubiquitin-proteasome system [1].
价 格：￥电议型 号：T75020产 地：中国大陆
