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  • T79488RNase L-IN-1；化合物 RNase L-IN-1RNase L-IN-1

    RNase L-IN-1 (compound 17a) functions as an inhibitor of RNase L (Ribonuclease L), an enzyme responsible for RNA degradation to inhibit viral replication, and plays a crucial role in mediating innate immune responses and inflammation [1].

    价 格：￥电议型 号：T79488产 地：中国大陆

  • T78345Ribonuclease A；核糖核酸酶AEC 3.1.27.5|||RNase A；EC 3.1.27.5|||RNase A

    Ribonuclease A (RNase A) is a potent endonuclease that removes RNA during dna and protein preparation.

    价 格：￥电议型 号：T78345产 地：中国大陆

  • T76249LRNAENFDRF TFA；化合物 RNAENFDRF TFARNAENFDRF TFA

    RNAENFDRF (βIIPKC624-632) TFA is conjugated to the cell permeable peptide TAT47-57, which can be used to form an inhibitory peptide SAMβA. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats [1] .

    价 格：￥电议型 号：T76249L产 地：中国大陆

  • T76249RNAENFDRF；化合物 RNAENFDRFRNAENFDRF

    RNAENFDRF (βIIPKC624-632) conjugated to TAT47-57, a cell-permeable peptide, forms SAMβA, a rationally designed peptide that selectively antagonizes Mfn1-βIIPKC association. SAMβA acts as a selective inhibitor of mitofusin 1-βIIPKC association, demonstrating improved heart failure outcomes in rats [1].

    价 格：￥电议型 号：T76249产 地：中国大陆

  • T75394Picornain 3C；化合物 Picornain 3CPicornain 3C

    Picornain 3C, a protease present in picornaviruses, exhibits endopeptidase activity by specifically cleaving Gln-Gly bonds within the poliovirus polyprotein and, through substitution, cleaves Glu for Gln, and Ser or Thr for Gly in other picornaviruses. This protease operates on non-terminal sequences and intermediates between serine peptidase chymotrypsin and cysteine peptidase papain, showcasing its role in viral polyprotein processing [1].

    价 格：￥电议型 号：T75394产 地：中国大陆

  • T75116COVID-19 Spike Protein mRNA-LNP；化合物 COVID-19 Spike Protein mRNA-LNPCOVID-19 Spike Protein mRNA-LNP

    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface, designed for applications such as RNA delivery, translation efficiency, and cell viability assessment. This spike protein facilitates the COVID-19 virus´s entry into host cells by binding to cell membrane receptors and enabling membrane fusion, making it a critical focal point for host neutralizing antibodies and vaccine developmen

    价 格：￥电议型 号：T75116产 地：中国大陆

  • T75115CD19 car circRNA-LNP；化合物 CD19 car circRNA-LNPCD19 car circRNA-LNP

    CD19 car circRNA-LNP, a lipid nanoparticle containing CD19 car circRNA, is designed for applications in RNA delivery, translation efficiency, and cell viability assessment. This compound is utilized in chimeric antigen receptor T cell immunotherapy (CAR-CD19), leveraging CD19 car, a chimeric antigen receptor that targets CD19. CD19, a CD molecule found on B cells (i.e., leukocyte differentiation antigen), plays a crucial role in B cell proliferation, differentiation, activation, and antibody pro

    价 格：￥电议型 号：T75115产 地：中国大陆

  • T75114CD19 car mRNA-LNP；化合物 CD19 car mRNA-LNPCD19 car mRNA-LNP

    CD19 car mRNA-LNP, a lipid nanoparticle (LNP) encapsulating CD19 car mRNA, is instrumental in assessing RNA delivery, translation efficacy, and cell viability among other applications. This compound is pivotal for chimeric antigen receptor T cell immunotherapy (CAR-CD19), leveraging the CD19 molecule - a critical membrane antigen expressed by B cells (i.e., leukocyte differentiation antigen) that plays a significant role in their proliferation, differentiation, activation, and antibody productio

    价 格：￥电议型 号：T75114产 地：中国大陆

  • T75104CD19 CAR circRNA；化合物 CD19 CAR circRNACD19 CAR circRNA

    CD19 CAR circRNA, expressing CD19 car protein, is utilized in chimeric antigen receptor T cell immunotherapy (CAR-CD19). This compound involves a chimeric antigen receptor, CD19, a CD molecule present on B cells (i.e., leukocyte differentiation antigen), crucial for B cell proliferation, differentiation, activation, and antibody production, and facilitates BCR signal transduction.

    价 格：￥电议型 号：T75104产 地：中国大陆

  • T75103CD19 CAR mRNA；化合物 CD19 CAR mRNACD19 CAR mRNA

    CD19 CAR mRNA is designed to express the CD19 chimeric antigen receptor (CAR) protein, pivotal in chimeric antigen receptor T cell (CAR-CD19) immunotherapy. This receptor targets CD19, a membrane antigen crucial for B cell proliferation, differentiation, activation, and antibody synthesis, playing a significant role in promoting BCR signal transduction.

    价 格：￥电议型 号：T75103产 地：中国大陆

  • T75102COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)；化合物 COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)COVID

    The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike protein facilitates virus entry into cells by binding to host cell membrane receptors and promoting membrane fusion. It serves as a significant action site for neutralizing antibodies and represents a primary focus in vaccine development [1].

    价 格：￥电议型 号：T75102产 地：中国大陆

  • T75031Pirnabine；化合物 PirnabinePirnabine

    Pirnabine, a cannabinoid receptor ligand, is utilized in glaucoma research [1].

    价 格：￥电议型 号：T75031产 地：中国大陆

  • T74886RNA splicing modulator 3；化合物 RNA splicing modulator 3RNA splicing modulator 3

    RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].

    价 格：￥电议型 号：T74886产 地：中国大陆

  • T74885RNA splicing modulator 2；化合物 RNA splicing modulator 2RNA splicing modulator 2

    RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .

    价 格：￥电议型 号：T74885产 地：中国大陆

  • T74884RNA splicing modulator 1；化合物 RNA splicing modulator 1RNA splicing modulator 1

    RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].

    价 格：￥电议型 号：T74884产 地：中国大陆

  • T74869SiRNA Negative Control；化合物 SiRNA Negative ControlSiRNA Negative Control

    siRNA Negative Control, a 21-nucleotide siRNA, serves as a negative control.

    价 格：￥电议型 号：T74869产 地：中国大陆

  • T74631RNA polymerase II-IN-2；化合物 RNA polymerase II-IN-2RNA polymerase II-IN-2

    RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α-amanitin in CHO and HEK293 cells, respectively [1].

    价 格：￥电议型 号：T74631产 地：中国大陆

  • T74630RNA polymerase II-IN-1；化合物 RNA polymerase II-IN-1RNA polymerase II-IN-1

    RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells compared to α-Amanitin [1].

    价 格：￥电议型 号：T74630产 地：中国大陆

  • T74612Aminoacyl tRNA synthetase-IN-2；化合物 Aminoacyl tRNA synthetase-IN-2Aminoacyl tRNA synthetase-IN-2

    Aminoacyl tRNA Synthetase-IN-2 (Compound 14) serves as an inhibitor of aminoacyl-tRNA synthetase (aaRS), presenting potential for the formulation of a novel class of antibiotics [1].

    价 格：￥电议型 号：T74612产 地：中国大陆

  • T7099Gefarnate；吉法酯Gefarnate

    Gefarnate is a synthetic compound used for the treatment of gastric ulcers,and also used in the treatment of dry eye syndrome.

    价 格：￥电议型 号：T7099产 地：中国大陆

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