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  • T75119KRASG12Cu00A0IN-2；化合物 KRASG12Cu00A0IN-2KRASG12Cu00A0IN-2

    KRASG12C IN-2 (compound 17) is an orally active inhibitor of KRAS G12C, which effectively suppresses tumor growth in mice [1].

    价 格：￥电议型 号：T75119产 地：中国大陆

  • T73469SG2057；化合物 SG2057DRG16；DRG16

    SG2057 (DRG16), a potent antitumor agent, is a pyrrolobenzodiazepine (PBD) dimer connected by a pentyldioxy linkage. This compound selectively binds to the minor groove of DNA, forming both interstrand and intrastrand cross-linked adducts, contributing to its high antitumor activity.

    价 格：￥电议型 号：T73469产 地：中国大陆

  • T71947SGK1 inhibitor；化合物 SGK1 inhibitorSGK1 inhibitor

    SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3β in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kα inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.

    价 格：￥电议型 号：T71947产 地：中国大陆

  • T71581SGX393；化合物 SGX393SGX393

    SGX393 is an inhibitor of the CML mutant Bcr-AblT315I, thereby preempting in vitro resistance when combined with nilotinib or dasatinib.

    价 格：￥电议型 号：T71581产 地：中国大陆

  • T71181GSK256073 Tris；化合物 GSK256073 TrisGSK256073 Tris

    GSK256073 is an agonist of G-protein coupled receptor 109A (GPR109A). It acts by reducing serum glucose in subjects with type 2 diabetes mellitus.

    价 格：￥电议型 号：T71181产 地：中国大陆

  • T7108Omberacetam；化合物NoopeptSGS-111|||Noopept|||GVS-111；SGS-111|||Noopept|||GVS-111

    Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.

    价 格：￥电议型 号：T7108产 地：中国大陆

  • T7089SGC2085；化合物SGC2085SGC2085

    SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).

    价 格：￥电议型 号：T7089产 地：中国大陆

  • T70100SG3-179；化合物 SG3-179SG3-179

    SG3-179 is a BET inhibitor.

    价 格：￥电议型 号：T70100产 地：中国大陆

  • T6982SGI-7079；化合物SGI7079SGI-7079

    SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance.

    价 格：￥电议型 号：T6982产 地：中国大陆

  • T69580SGC6870；化合物 SGC6870SGC6870

    SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.

    价 格：￥电议型 号：T69580产 地：中国大陆

  • T69551SGC-STK17B-1；化合物 SGC-STK17B-1SGC-STK17B-1

    SGC-STK17B-1 is a potent and selective inhibitor of STK17B/DRAK2 kinase.

    价 格：￥电议型 号：T69551产 地：中国大陆

  • T6871L-Glutamic acid monosodium salt；谷氨酸单钠盐Monosodium glutamate|||Glutacyl|||Glutavene|||Ajinomoto|||MSG；

    L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.

    价 格：￥电议型 号：T6871产 地：中国大陆

  • T6668SGC-CBP30；化合物SGC-CBP30SGC-CBP30

    SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).

    价 格：￥电议型 号：T6668产 地：中国大陆

  • T64365SG-094；化合物SG-094SG-094

    SG-094 is a specific TPC2 inhibitor that shows anti-proliferative effects on RIL175 cells with an IC50 of 3.7μM and can be used in tumor research.

    价 格：￥电议型 号：T64365产 地：中国大陆

  • T63741SGK1-IN-3；化合物 SGK1-IN-3SGK1-IN-3

    SGK1-IN-3 is a potent, orally active SGK1 inhibitor. Among them, the serine/threonine kinase SGK1, an activator of the β-linked protein pathway and a powerful stimulator of cartilage degradation, has been found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 shows research potential in osteoarthritis.

    价 格：￥电议型 号：T63741产 地：中国大陆

  • T62909SGC agonist 2；化合物 SGC agonist 2SGC agonist 2

    SGC agonist 2 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 2 has potential for cardiovascular disease (heart failure, angina, pulmonary hypertension, myocardial infarction) and fibrotic disease (renal fibrosis, systemic sclerosis).

    价 格：￥电议型 号：T62909产 地：中国大陆

  • T62830SGLT1/2-IN-1；化合物 SGLT1/2-IN-1SGLT1/2-IN-1

    SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.

    价 格：￥电议型 号：T62830产 地：中国大陆

  • T62471SGC agonist 1；化合物 SGC agonist 1SGC agonist 1

    SGC agonist 1 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 1 is able to increase solubility and has high cell permeability.

    价 格：￥电议型 号：T62471产 地：中国大陆

  • T61268Vutiglabridin；化合物VutiglabridinHSG4112；HSG4112

    Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stability. vutiglabridin ameliorates mptp-induced neurodegeneration in Parkinson´s disease mice by targeting mitochondrial paraoxonase-2. Vutiglabridin is a clinical phase 2 drug for the treatment of obesity and has therapeutic effects on p-mitochondrial PON2 in a PD model. vutigla

    价 格：￥电议型 号：T61268产 地：中国大陆

  • T61151Beclobrate；贝罗贝特Sgd 24774；Sgd 24774

    Beclobrate (Sgd 24774) is a novel orally available fibric acid derivative that has shown significant lipid and cholesterol-lowering activity in rodents and may be used in the study of primary hyperlipoproteinemia.

    价 格：￥电议型 号：T61151产 地：中国大陆

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