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产品数:86101
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T6824EAI045Inhibitor,Epidermal growth factor receptor,ErbB-1,EGFR,EAI-045,EAI 045,inhibit,HER1,EAI045
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
价 格:¥电议型 号:T6824产 地:中国大陆
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T6718ZingeroneZingerone,Nuclear factor-kappaB,inhibit,Nuclear factor-κB,Inhibitor,NF-κB
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.
价 格:¥电议型 号:T6718产 地:中国大陆
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TMA0507TomatidineJNK,Tomatidine,Nuclear factor-κB,inhibit,NF-κB,Autophagy,Nuclear factor-kappaB,Inhibitor,E
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. It activates autophagy either in mammal cells or C elegans.
价 格:¥电议型 号:TMA0507产 地:中国大陆
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TN1131HandelinNuclear factor-κB,Inhibitor,Handelin,Nuclear factor-kappaB,inhibit,NF-κB
Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.
价 格:¥电议型 号:TN1131产 地:中国大陆
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T6S1538Neochlorogenic acidNuclear factor-κB,Interleukin Related,Tumor Necrosis Factor Receptor,NF-κB,Neochl
(E)-Neochlorogenic Acid is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
价 格:¥电议型 号:T6S1538产 地:中国大陆
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T8679Epidermal Growth FactorEpidermal Growth Factor
Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers.
价 格:¥电议型 号:T8679产 地:中国大陆
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T8981WAY-169916WAY-169916,Inhibitor,Nuclear factor-kappaB,inhibit,Estrogen Receptor/ERR,NF-κB,Nuclear fac
WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER). It acts by inhibiting NF-kB transcriptional activity but being devoid of conventional estrogenic activity.
价 格:¥电议型 号:T8981产 地:中国大陆
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T6039TAK-285EGFR,ErbB-1,HER2,Inhibitor,CNS,penetration,orally,Epidermal growth factor receptor,inhibit,an
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
价 格:¥电议型 号:T6039产 地:中国大陆
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T6S0659Rhynchophyllineinhibit,Rhynchophylline,Nuclear factor-κB,Nuclear factor-kappaB,Inhibitor,NF-κB
1. Rhynchophylline can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1,
价 格:¥电议型 号:T6S0659产 地:中国大陆
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T6S1543DehydrodiisoeugenolDehydrodiisoeugenol,COX,NF-κB,Inhibitor,Nuclear factor-κB,Cyclooxygenase,Bacteria
1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated phosphorylation-dependent proteolysis of inhibitor κB-α and transcriptional activity of NF-κB in the cells.
价 格:¥电议型 号:T6S1543产 地:中国大陆
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TD0099Malachite green oxalatephosphate,p65,IKK,Nuclear factor-kappaB,NF-κB,IKBKE,enzymatic,Malachite green
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.
价 格:¥电议型 号:TD0099产 地:中国大陆
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T9460iMDKinhibit,iMDK,midkine,factor,PI3K,NSCLC,growth,Inhibitor,Phosphoinositide 3-kinase,MDK
iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors without harming normal cells and mice.
价 格:¥电议型 号:T9460产 地:中国大陆
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T7104Dovitinib lactateFGFR,CHIR-258,Dovitinib,c-Kit,SCFR,PDGFR,CD117,Platelet-derived growth factor recep
Dovitinib lactate(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
价 格:¥电议型 号:T7104产 地:中国大陆
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T9905CetuximabInhibitor,Epidermal growth factor receptor,ErbB-1,inhibit,EGFR,Cetuximab,C-225,C 225,HER1
Cetuximab (anti-EGFR) a novel molecular-targeted agentis an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation.
价 格:¥电议型 号:T9905产 地:中国大陆
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T6381Amifostine trihydrateDNA-damage,thiol,HIF-PH,cytoprotective,Broad-spectrum,Hypoxia-inducible factors
Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
价 格:¥电议型 号:T6381产 地:中国大陆
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T6823E3330pancreatic cancer,TNF-α,E3330,REF-1,NF-κB,HIFs,Inhibitor,HIF-PH,Nuclear factor-kappaB,APX-3330,
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
价 格:¥电议型 号:T6823产 地:中国大陆
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TQ0131RocaglamideNF-κB,Nuclear factor-kappaB,Heat shock proteins,inhibit,Rocaglamide,Eukaryotic Initiation
Rocaglamide, isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.
价 格:¥电议型 号:TQ0131产 地:中国大陆
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TN10511-Caffeoylquinic acidinhibit,NF-κB,Nuclear factor-kappaB,Nuclear factor-κB,1-Caffeoylquinic acid,Inh
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal.
价 格:¥电议型 号:TN1051产 地:中国大陆
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T9625SandaloreInhibitor,Apoptosis,Sandalore,IGF-1,spontaneous,olfactory receptor,hair growth,inhibit,foll
Sandalore prolongs human hair growth by decreasing apoptosis and increasing the production of the anagen-prolonging growth factor IGF-1 in the outer root sheath. Sandalore is a selective agonist of olfactory receptor OR2AT4.
价 格:¥电议型 号:T9625产 地:中国大陆
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T8491VorolanibVEGFR,PDGFR,X82,Vascular endothelial growth factor receptor,CM 082,transporter,angiogenesis
Vorolanib is an orally active VEGFR/PDGFR dual inhibitor.
价 格:¥电议型 号:T8491产 地:中国大陆