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T27714KB-141;化合物 T27714KB-141
KB-141 is an agonist of thyroid hormone receptor.
价 格:¥电议型 号:T27714产 地:中国大陆
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T27713KB-130015;化合物 T27713KB-130015
KB-130015, a activator of hERG1 potassium channels, blocks native and recombinant hERG1 channels at high voltages.
价 格:¥电议型 号:T27713产 地:中国大陆
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T26776Berteroin;化合物 T26776OR-009512|||KB-47947|||LP-088984|||KB47947|||LP088984;OR-009512|||KB-47947|||LP-
Berteroin is an erucin homolog and potential antioxidant. It is present in cruciferous vegetables, including rucola salad leaves, Chinese cabbage and mustard oil. It decreases the release of pro-inflammatory cytokines in LPS-stimulated macrophages. It also decreases expression of androgen receptors in prostate cancer cells.
价 格:¥电议型 号:T26776产 地:中国大陆
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T25566KBH-A42;化合物 T25566KBH-A-42|||KBHA42|||KBH-A 42|||KBH A 42;KBH-A-42|||KBHA42|||KBH-A 42|||KBH A 42
KBH-A42 is an inhibitor of histone deacetylase.
价 格:¥电议型 号:T25566产 地:中国大陆
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T24255KB 5666;化合物 T24255KB-5666|||KB5666;KB-5666|||KB5666
KB 5666, a quinazoline derivative, is a lipid peroxidation inhibitor. It protects the brain from both cellular and functional consequences of ischemia.
价 格:¥电议型 号:T24255产 地:中国大陆
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T24254KB-5492 anhydrous;化合物 T24254KB-5492|||KB5492|||KB 5492;KB-5492|||KB5492|||KB 5492
KB 5492 is an agent of anti-ulcer. It preventing cysteamine-induced duodenal ulcers by stimulating duodenal HCO3- secretion.
价 格:¥电议型 号:T24254产 地:中国大陆
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T2327Pelitinib;培利替尼EKB-569|||WAY-EKB 569;培利替尼|||EKB-569|||WAY-EKB 569
Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).
价 格:¥电议型 号:T2327产 地:中国大陆
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T22343HKB99;化合物 T22343HKB99
HKB99 is a mutational inhibitor of phosphoglycerate mutase 1 (PGAM1).HKB99 increases oxidative stress, activates JNK/c-Jun, and inhibits AKT and ERK[1].HKB99 inhibits the formation of invasive pseudopods and raises the level of PAI-2.HKB99 can be used for the study of non-small cell lung cancer (NSCLC)[2].
价 格:¥电议型 号:T22343产 地:中国大陆
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T21453AP-24600;化合物 T21453OZ477A282R|||AP 24600|||DA-12847|||KB-310048|||UNII-OZ477A282R;OZ477A282R|||AP 24
AP-24600 is a bio-active chemical.
价 格:¥电议型 号:T21453产 地:中国大陆
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T21388Emedastine Difumarate富马酸依美斯汀Rapimine|||DSSTox_CID_26911|||AL-3432A|||富马酸依美斯汀|||KB-2413|||Emedastine
Emedastine Difumarate is a selective histamine H1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva.
价 格:¥电议型 号:T21388产 地:中国大陆
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T2062kb NB 142-70;化合物kb NB 142-70kb NB 142-70
kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).
价 格:¥电议型 号:T2062产 地:中国大陆
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T19774Methylisothiazolinone甲基异噻唑啉酮KB-838|||MI|||N-Methylisothiazolin-3-one|||甲基异噻唑啉酮|||Methylisothiazolino
Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.
价 格:¥电议型 号:T19774产 地:中国大陆
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T18611AP1867-2-(carboxymethoxy);化合物 T18611PROTAC FKBP12-binding moiety 2;PROTAC FKBP12-binding moiety 2
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
价 格:¥电议型 号:T18611产 地:中国大陆
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T18610PROTAC FKBP Degrader-3;化合物 T18610PROTAC FKBP Degrader-3
PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].
价 格:¥电议型 号:T18610产 地:中国大陆
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T18597dFKBP-1;化合物 T18597dFKBP-1
dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
价 格:¥电议型 号:T18597产 地:中国大陆
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T1808kb-NB77-78;化合物kb-NB77-78kb-NB77-78
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
价 格:¥电议型 号:T1808产 地:中国大陆
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T18061KB02-SLF;化合物 T18061KB02-SLF
KB02-SLF is a PROTAC-based nuclear FKBP12 degrader, known as a molecular glue. It facilitates the degradation of nuclear FKBP12 by covalently modifying DCAF16, an E3 ligase. Moreover, KB02-SLF enhances the longevity of protein degradation in biological systems. The compound SLF acts as a linker, binding to the ubiquitin E3 ligase ligand KB02, resulting in the formation of KB02-SLF[1].
价 格:¥电议型 号:T18061产 地:中国大陆
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T18060KB02-JQ1;化合物 T18060KB02-JQ1
KB02-JQ1 is a potent and specific proteolysis targeting chimera (PROTAC) that specifically degrades BRD4, acting as a molecular glue. It does not degrade BRD2 or BRD3. The mechanism of action involves covalent modification of the E3 ligase DCAF16, thereby promoting BRD4 degradation. Importantly, KB02-JQ1 demonstrates enhanced stability and durability in facilitating protein degradation within biological systems. The compound forms a complex with the ubiquitin E3 ligase ligand KB02 through a link
价 格:¥电议型 号:T18060产 地:中国大陆
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T16724Razuprotafib;化合物RazuprotafibAKB-9778;AKB-9778
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ? (HPTP?) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.
价 格:¥电议型 号:T16724产 地:中国大陆