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T19433Monocrotaline N-OxideMonocrotaline N-Oxide
Monocrotaline N-Oxide is a monocrotaline metabolite.
价 格:¥电议型 号:T19433产 地:美洲
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T2181Scopolamine N-oxide HBrScopolamine N-oxide HBr,Hyoscine N-oxide hydrobromide,Scopolamine N-oxide hyd
Scopolamine N-oxide HBr is an antagonist of the muscarinic acetylcholine.
价 格:¥电议型 号:T2181产 地:美洲
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T2724Caryophyllene oxideCaryophyllene oxide
Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity.
价 格:¥电议型 号:T2724产 地:美洲
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T5247Trimethylamine N-oxide dihydrateTrimethylamine N-oxide dihydrate,TMANO Dihydrate,
Trimethylamine N-oxide (TMAO) is an oxidation product of trimethylamine and a common metabolite in animals and humans. In particular, trimethylamine-N-oxide is biosynthesized endogenously from trimethylamine, which is derived from choline, which can be de
价 格:¥电议型 号:T5247产 地:美洲
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T5857Trametinib DMSO solvateTrametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfox
Trametinib DMSO solvate is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)
价 格:¥电议型 号:T5857产 地:美洲
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T8698Hydrazinium hydroxide;化合物Hydrazinium hydroxideHydrazinium hydroxide
Hydrazinium hydroxide is a fluorinated carboxylic acid that has been used to study the mechanisms of action of enzymes, hormones and other biomolecules. It has also been used to study the effects of various drugs on the body and to study the effects of environmental toxins on the body.
价 格:¥电议型 号:T8698产 地:中国大陆
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T8615ISOTHIAZOLINE 1,1-DIOXIDE;异噻唑烷 1,1-二氧化物isothiazolidine 1,1-dioxide;异噻唑烷 1,1-二氧化物|||isothiazolidine 1
ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors, and in the preparation of cryptochrome imhibitors as antidiabetic agents.
价 格:¥电议型 号:T8615产 地:中国大陆
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T83896Promethazine Sulfoxide;化合物 Promethazine SulfoxidePromethazine Sulfoxide
Promethazine sulfoxide, a metabolite of the histamine H1 receptor antagonist promethazine, is produced via the action of the cytochrome P450 (CYP) isoform CYP2D6, converting promethazine into this compound.
价 格:¥电议型 号:T83896产 地:中国大陆
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T83857Soluble Epoxide Hydrolase PROTAC 1a;化合物 Soluble Epoxide Hydrolase PROTAC 1asEH Proteolysis-targeting
Soluble epoxide hydrolase (sEH) PROTAC 1a is a proteolysis-targeting chimera (PROTAC) comprising a cereblon ligand linked to the sEH inhibitor t-TUCB via a linker, promoting selective sEH degradation and inhibiting its hydrolase activity (IC50 = 0.8 nM) significantly more than its phosphatase activity (IC50 = >10,000 nM). This compound preferentially targets cytosolic sEH for lysosomal rather than proteasomal degradation. Furthermore, it mitigates thapsigargin-induced upregulation of phosphoryla
价 格:¥电议型 号:T83857产 地:中国大陆
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T83780GPX4 24;化合物 GPX4 24Phospholipid Hydroperoxide Glutathione Peroxidase 24|||PHGPx 24|||Glutathione Per
GPX4 24, a derivative of (1S,3R)-RSL3, acts as a potent inhibitor of glutathione peroxidase 4 (GPX4) through covalent binding in a concentration-dependent manner within 4T1 murine mammary carcinoma cells. This compound effectively induces ferroptosis in GPX4-dependent HT-1080 fibrosarcoma cells with an EC50 value of 0.16 ?M. Additionally, at a dose of 200 mg/kg, GPX4 24 elevates malondialdehyde (MDA) levels in both kidney and plasma of mice, highlighting its impact on lipid peroxidation.
价 格:¥电议型 号:T83780产 地:中国大陆
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T83721Hexafluoropropylene Oxide Dimer Acid;化合物 Hexafluoropropylene Oxide Dimer AcidFRD-903|||Perfluoro-2-p
Hexafluoropropylene oxide dimer acid (HFPO-DA), a perfluoroalkyl ether carboxylic acid (PFECA), shows diverse biological impacts across species. At 250 ?M, it triggers apoptosis and enhances reactive oxygen species (ROS) levels in HepG2 cells. In hatchling chickens, HFPO-DA at a dosage of 4 mg/kg per egg notably decreases right ventricular wall thickness, accelerates heart rate, and promotes hepatic lipid accumulation, though these effects are mitigable by silencing the Ppara gene. It significan
价 格:¥电议型 号:T83721产 地:中国大陆
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T83538(R)-1-PeCSO;化合物 (R)-1-PeCSOIsoalliin|||trans-(+)-S-1-Propenyl-L-cysteine sulfoxide;Isoalliin|||trans
(R)-1-PeCSO, also known as trans-(+)-S-1-Propenyl-L-cysteine sulfoxide, constitutes the primary flavor precursor in onions [1].
价 格:¥电议型 号:T83538产 地:中国大陆
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T833902-C-methylene-myo-inositol oxide;化合物 2-C-methylene-myo-inositol oxideNSC 45109;NSC 45109
2-C-Methylene-myo-inositol oxide (NSC 45109), an inositol derivative, promotes pseudohyphal growth in Saccharomyces species [1].
价 格:¥电议型 号:T83390产 地:中国大陆
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T83214Abiraterone sulfate N-oxide;化合物 Abiraterone sulfate N-oxideAbiraterone sulfate N-oxide
Abiraterone sulfate N-oxide, a carboxylic acid and major metabolite of Abiraterone, is utilized in prostate cancer research [1] [2].
价 格:¥电议型 号:T83214产 地:中国大陆
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T82822Brassicanate A sulfoxide;化合物 Brassicanate A sulfoxideBrassicanate A sulfoxide
Brassicanate A sulfoxide, isolated from Brassica oleracea [1], exhibits herbicidal properties by inhibiting the biosynthesis of essential amino acids in plants. It operates by binding to key enzymes such as dihydroxyacid dehydratase (DHAD), hydroxymethylpyruvate dioxygenase (HPPD), acetolactate synthase (ALS), PYL family proteins, and transport inhibitor response 1 (TIR1), thereby reducing their enzymatic activity.
价 格:¥电议型 号:T82822产 地:中国大陆
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T8132Iron sucrose;蔗糖铁Iron saccharate|||Sucroferric oxyhydroxide;Iron saccharate|||蔗糖铁|||Sucroferric oxyhy
Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.
价 格:¥电议型 号:T8132产 地:中国大陆
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T81273Rinderine N-oxide;化合物 Rinderine N-oxideRinderine N-oxide
Rinderine N-oxide, a pyrrolizidine alkaloid, is present in R. graeca [1].
价 格:¥电议型 号:T81273产 地:中国大陆
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T80993Thioacetamide-S-oxide;化合物 Thioacetamide-S-oxideThioacetamide-S-oxide
Thioacetamide-S-oxide, a metabolite of Thiocetamide, functions as a δ-aminolevulinic acid (ALA) synthetase inhibitor [1].
价 格:¥电议型 号:T80993产 地:中国大陆
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T79981Nitric oxide production-IN-1;化合物 Nitric oxide production-IN-1Nitric oxide production-IN-1
Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis. It effectively suppresses NO synthesis in rat abdominal macrophages upon stimulation with lipopolysaccharide [1].
价 格:¥电议型 号:T79981产 地:中国大陆
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T78489Lotusine hydroxide;化合物 Lotusine hydroxideLotusine hydroxide
Lotusine (hydroxide), a pure alkaloid isolated from the green seed embryos of Nelumbo nucifera Gaertn, influences action potentials in myocardial tissue and the slow inward current in cardiac Purkinje fibers [1].
价 格:¥电议型 号:T78489产 地:中国大陆