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T36962MMP Inhibitor I (trifluoroacetate salt);MMP Inhibitor I (trifluoroacetate salt)MMP Inhibitor I (trif
MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, α-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.
价 格:¥电议型 号:T36962产 地:中国大陆
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T36864GRP (human) (trifluoroacetate salt);GRP (human) (trifluoroacetate salt)GRP (human) (trifluoroacetate
Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM.
价 格:¥电议型 号:T36864产 地:中国大陆
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T36777Thrombin Receptor Agonist Peptide (trifluoroacetate salt);Thrombin Receptor Agonist Peptide (trifluo
Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) increases the cytosolic calcium concentration in isolated guinea pig pulmonary smooth muscle cells 5-fold over baseline. It increases pulmonary arterial pressure in isolated guinea pig lung when used at a concentration of 1 μM, which is comparable to the effect induced by 10 nM α
价 格:¥电议型 号:T36777产 地:中国大陆
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T36767Parathyroid Hormone (1-13) (trifluoroacetate salt);Parathyroid Hormone (1-13) (trifluoroacetate salt
Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) .
价 格:¥电议型 号:T36767产 地:中国大陆
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T36729Urotensin II (goby) (trifluoroacetate salt);Urotensin II (goby) (trifluoroacetate salt)Urotensin II
Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 cells expressing human and rat UT (EC50s = 0.47 and 0.78 nM, respectively) but decreases intracellular calcium concentration in goby (G. mirabilis) enterocytes when used at a concentration of 500 nM.2Urotensin II (20 mU/ml) stimulates active sodium and chloride absorption across
价 格:¥电议型 号:T36729产 地:中国大陆
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T36722Deltorphin II (trifluoroacetate salt);Deltorphin II (trifluoroacetate salt)Deltorphin II (trifluoroa
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid
价 格:¥电议型 号:T36722产 地:中国大陆
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T36577K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt);K-Biotin-W-Histone H2B (108-125) (trifluoro
Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker. Histone H2B can be modified by addition of an O-linked N-acetylglucosamine (GlcNAc) moiety to the serine residue at position 112, which promotes monoubiquitination of the lysine at position 120.1 Both of these modifications are associated with active transcription. Histone H2B a
价 格:¥电议型 号:T36577产 地:中国大陆
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T36576Histone H3 (21-44)-GK-biotin (trifluoroacetate salt);Histone H3 (21-44)-GK-biotin (trifluoroacetate
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences and is biotinylated via a C-terminal GK linker. Histone H3 (21-44) contains a lysine residue at position 23 that is subject to acetylation, an arginine at position 26 subject to methylation, and a serine at position 28 subject to phosphorylation, as well as lysine residues at positions 27 and 36 that are subject to methylation and acetylation.
价 格:¥电议型 号:T36576产 地:中国大陆
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T36565Adrenomedullin (13-52) (human) (trifluoroacetate salt);Adrenomedullin (13-52) (human) (trifluoroacet
Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52) . It induces nitric oxide-dependent relaxation of and inhibits release of angiotensin II and endothelin-1 from isolated rat aorta.
价 格:¥电议型 号:T36565产 地:中国大陆
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T36555Tyr-α-CGRP (human) (trifluoroacetate salt);Tyr-α-CGRP (human) (trifluoroacetate salt)Tyr-α-CGRP (hum
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated rig
价 格:¥电议型 号:T36555产 地:中国大陆
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T36553Thrombin Receptor Peptide Ligand (trifluoroacetate salt);Thrombin Receptor Peptide Ligand (trifluoro
Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro). It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide in vitro when used at a concentration of 32 μM but does not affect platelet aggregation induced by ADP or collagen. It also inhibits thrombin- and TRAP-induced proliferation of vascular smooth muscle cells (VSMCs). Thrombin receptor peptide ligand (100 μmol/kg bolus, i.v
价 格:¥电议型 号:T36553产 地:中国大陆
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T36428PACAP-related Peptide (human) (trifluoroacetate salt);PACAP-related Peptide (human) (trifluoroacetat
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in normal human pancreas and adrenal gland tissue and in some tumors that produce vasoactive intestinal peptide (VIP). PRP (1-29) is secreted by CHO-K1 cells that express human recombinant preproPACAP.
价 格:¥电议型 号:T36428产 地:中国大陆
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T36427PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt);PACAP (6-27) (huma
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y,
价 格:¥电议型 号:T36427产 地:中国大陆
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T36380GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt);GLP-1 (1-36) amide (human, rat) (trifluoroac
GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.
价 格:¥电议型 号:T36380产 地:中国大陆
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T36377Somatorelin (1-44) amide (human) (trifluoroacetate salt);Somatorelin (1-44) amide (human) (trifluoro
Somatorelin (1-44) amide is a synthetic peptide that corresponds to the full 44-amino acid sequence of growth hormone-releasing hormone (GHRH), a hormone that stimulates the production of growth hormone from the pituitary gland and is involved in the regulation of cell proliferation and differentiation.1,2Somatorelin induces growth hormone release similarly to GHRHin vitroandin vivo.1
价 格:¥电议型 号:T36377产 地:中国大陆
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T36373Urocortin II (mouse) (trifluoroacetate salt);Urocortin II (mouse) (trifluoroacetate salt)Urocortin I
Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.
价 格:¥电议型 号:T36373产 地:中国大陆
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T363682H-Cho-Arg (trifluoroacetate salt);2H-Cho-Arg (trifluoroacetate salt)2H-Cho-Arg (trifluoroacetate sa
2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin and t
价 格:¥电议型 号:T36368产 地:中国大陆
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T36363Dnp-RPLALWRS (trifluoroacetate salt);Dnp-RPLALWRS (trifluoroacetate salt)Dnp-RPLALWRS (trifluoroacet
Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). The activity of MMP-7 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.
价 格:¥电议型 号:T36363产 地:中国大陆
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T36362Dnp-PLGMWSR (trifluoroacetate salt);Dnp-PLGMWSR (trifluoroacetate salt)Dnp-PLGMWSR (trifluoroacetate
Dnp-PLGMWSR is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-9. The activity of MMP-2 and MMP-9 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.
价 格:¥电议型 号:T36362产 地:中国大陆
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T36361Dnp-PLALWAR (trifluoroacetate salt);Dnp-PLALWAR (trifluoroacetate salt)Dnp-PLALWAR (trifluoroacetate
Dnp-PLALWAR is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-8. The activity of MMP-1 and MMP-8 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.
价 格:¥电议型 号:T36361产 地:中国大陆