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T16474Petesicatib;化合物 T16474Petesicatib
Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
价 格:¥电议型 号:T16474产 地:中国大陆
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T16465Penicillin G benzathine苄星青霉素Benzathine benzylpenicillin|||Benzathine penicilline G
Penicillin G benzathine has anti-bacterial infectious activity and can be used to study early syphilis.
价 格:¥电议型 号:T16465产 地:中国大陆
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T16451PEAQX tetrasodium hydrate;PEAQX四钠水合物NVP-AAM077 tetrasodium hydrate|||PEAQX tetrasodium hydrate (4598
PEAQX tetrasodium hydrate (PEAQX tetrasodium hydrate (459836-30-7 free base)) is an orally available NMDA antagonist that is potent and selective. The IC50 value of PEAQX tetrasodium hydrate (459836-30-7 free base) against hNMDAR 1A/2A was 270 nM and 29600 nM against hNMDAR 1A/2B, respectively.
价 格:¥电议型 号:T16451产 地:中国大陆
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T16440Ibrutinib Racemate化合物 T16440PCI-32765 (Racemate)
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.
价 格:¥电议型 号:T16440产 地:中国大陆
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T16434PAT-048;化合物 T16434PAT-048
PAT-048 is an effective and selective autotaxin inhibitor. PAT-048 reduces dermal fibrosis in vivo. PAT-048 also inhibits IL-6 mRNA expression but displays no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in the lung fibrosis model. PAT-048 has an IC50 and IC90 of 20 nM and 200 nM for autotaxin in mouse plasma.
价 格:¥电议型 号:T16434产 地:中国大陆
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T16431Pamatolol;氨甲酯心定Pamatolol
Pamatolol is a selective and potent beta-adrenoceptor antagonist that has not shown sympathomimetic activity in ex vivo experiments.
价 格:¥电议型 号:T16431产 地:中国大陆
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T16426Asivatrep;化合物 T16426PAC-14028;PAC-14028
Asivatrep is an effective and selective transient receptor potential vanilloid type I antagonist.
价 格:¥电议型 号:T16426产 地:中国大陆
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T16418Oxyfenamate;奥芬达唑P 301|||Oxyphenamate;P 301|||Oxyphenamate|||奥芬达唑
Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.
价 格:¥电议型 号:T16418产 地:中国大陆
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T16415Oxamflatin;化合物 T16415Metacept-3;Metacept-3
Oxamflatin is an effective inhibitor of HDAC (IC50: 15.7 nM).
价 格:¥电议型 号:T16415产 地:中国大陆
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T1641Strontium ranelate;雷尼酸锶Calcium-sensing receptor|||Distrontium renelate|||Distrontium renelate|||S 12
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in the treatment of severe osteoporosis.
价 格:¥电议型 号:T1641产 地:中国大陆
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T16406Orvepitant maleate;化合物 T16406GW823296 maleate;GW823296 maleate
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.
价 格:¥电议型 号:T16406产 地:中国大陆
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T16383Olinciguat;化合物OlinciguatIW-1701;IW-1701
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
价 格:¥电议型 号:T16383产 地:中国大陆
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T16376Odevixibat;奥德昔巴特A4250;A4250
Odevixibat (A4250) is an effective, selective and orally active ileal bile acid transporter inhibitor. Odevixibat has the potential for the treatment of primary biliary cirrhosis. Odevixibat reduces cholestatic liver and bile duct injury in mice model.
价 格:¥电议型 号:T16376产 地:中国大陆
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T1637Deferoxamine Mesylate甲磺酸去铁胺desferrioxamine B|||Desferrioxamine B mesylate|||DFO|||DFOM|||去铁铵|||甲磺酸去铁
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and induces apoptosis.
价 格:¥电议型 号:T1637产 地:中国大陆
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T1636LParoxetine hydrochloride hemihydrate;盐酸帕罗西汀半水合物Paroxetine Hydrochloride|||Paxil|||Paroxetine HCl|||S
Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).
价 格:¥电议型 号:T1636L产 地:中国大陆
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T16364Infigratinib phosphate;磷酸英非替尼NVP-BGJ398 phosphate|||BGJ-398 phosphate;NVP-BGJ398 phosphate|||BGJ-398
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
价 格:¥电议型 号:T16364产 地:中国大陆
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T16342KL1333;化合物KL1333NQO1 activator 1;NQO1 activator 1
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.
价 格:¥电议型 号:T16342产 地:中国大陆
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T16338Norgestimate metabolite Norelgestromin甲基孕酮17-Deacetyl norgestimate|||17-Deacylnorgestimate|||甲基孕酮
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl estradiol.
价 格:¥电议型 号:T16338产 地:中国大陆
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T16332NKH477;化合物 T16332Colforsin dapropate hydrochloride;Colforsin dapropate hydrochloride
NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts. NKH477 directly activates the catalytic unit of adenylate cyclase and enhances intracellular cAMP .
价 格:¥电议型 号:T16332产 地:中国大陆
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T16288Neuropathiazol;化合物NeuropathiazolNeuropathiazol
Neuropathiazol causes neuronal differentiation of adult hippocampal neural progenitor cells.
价 格:¥电议型 号:T16288产 地:中国大陆