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T11497Ganfeborole HCl;Ganfeborole 盐酸盐GSK3036656 HCl|||GSK656 HCl;GSK3036656 HCl|||GSK656 HCl
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM).
价 格:¥电议型 号:T11497产 地:中国大陆
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T1125Shikonin;紫草素NSC 252844|||Isoarnebin 4|||(+)-Shikonin|||Alkanna Red|||C.I. 75535|||Anchusa acid;NSC 2
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
价 格:¥电议型 号:T1125产 地:中国大陆
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T11143EB-47;化合物EB-47EB-47
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.
价 格:¥电议型 号:T11143产 地:中国大陆
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T10977DCEBIO;化合物DCEBIODCEBIO
DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84 colon cells.
价 格:¥电议型 号:T10977产 地:中国大陆
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T1084Apramycin sulfate;硫酸安普霉素Nebramycin II|||Ai3-29795;Nebramycin II|||Ai3-29795|||硫酸安普霉素|||硫酸阿布拉霉素
Apramycin sulfate (Nebramycin II) is an aminoglycoside antibiotic.
价 格:¥电议型 号:T1084产 地:中国大陆
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T10765Eragidomide;化合物 EragidomideCC-90009|||Cereblon modulator 1;CC-90009|||Cereblon modulator 1
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.
价 格:¥电议型 号:T10765产 地:中国大陆
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T10758LCentanafadine hydrochloride;化合物Centanafadine hydrochlorideEB-1020 hydrochloride;EB-1020 hydrochlorid
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
价 格:¥电议型 号:T10758L产 地:中国大陆
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T10758Centanafadine;化合物 T10758EB-1020;EB-1020
Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
价 格:¥电议型 号:T10758产 地:中国大陆
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T10749Cebranopadol ((1α,4α)stereoisomer);化合物 T10749GRT6005 (1α,4α)stereoisomer;GRT6005 (1α,4α)stereoisomer
Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol which is a potent ORL-1 agonist.
价 格:¥电议型 号:T10749产 地:中国大陆
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T10680Carebastine;卡依巴司丁Carebastine
Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor.
价 格:¥电议型 号:T10680产 地:中国大陆
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T10631LBucindolol Formate;化合物Bucindolol FormateBucindolol Formate (71119-11-4 Free base);Bucindolol Formate
Bucindolol Formatel is a blocker of β1-adrenergic receptor. Bucindolol exhibits intrinsic sympathomimetic activity. Bucindolol can be used in the research of heart failure.
价 格:¥电议型 号:T10631L产 地:中国大陆
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T10591BPO-27 racemate;化合物BPO-27 racemateBPO-27 (racemate);BPO-27 (racemate)
BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.
价 格:¥电议型 号:T10591产 地:中国大陆
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T10565BMS-1001 hydrochloride;化合物BMS-1001 hydrochlorideBMS-1001 hydrochloride
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.
价 格:¥电议型 号:T10565产 地:中国大陆
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T1053Mebeverine hydrochloride;盐酸麦皮凡林Colofac Hydrochloride|||Duspatalin Hydrochloride|||Duspatal Hydrochlo
Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.
价 格:¥电议型 号:T1053产 地:中国大陆
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T10513Benzothiohydrazide化合物 BenzothiohydrazideBenzothiohydrazide
Benzothiohydrazide is an analog of isoniazid with anti-tuberculosis activity and can be used to isolate fungi and bacteria.
价 格:¥电议型 号:T10513产 地:中国大陆
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T10468Elimusertib hydrochloride(1876467-74-1 free base);化合物 Elimusertib hydrochlorideBAY-1895344 hydrochlo
Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor activity.
价 格:¥电议型 号:T10468产 地:中国大陆
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T10229Acebutolol D7;化合物 T10229Acebutolol D7
Acebutolol D7 is a deuterium-labeled Acebutolol. Acebutolol is a selective antagonist of the β1 adrenergic receptor used in the treatment of angina pectoris, hypertension, and cardiac arrhythmias.
价 格:¥电议型 号:T10229产 地:中国大陆
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T1012Acebutolol hydrochloride盐酸醋丁洛尔盐酸醋丁洛尔|||Acebutolol HCl
Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol hydrochloride is used in ventricular arrhythmias. Other indications include hypertension
价 格:¥电议型 号:T1012产 地:中国大陆
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T0918Trimebutine;曲美布汀Mebutin;曲美布汀|||Mebutin
Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders. It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. Trimebut
价 格:¥电议型 号:T0918产 地:中国大陆
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T0825Ebselen;依布硒SPI-1005|||PZ-51|||CCG-39161;SPI-1005|||PZ-51|||依布硒|||CCG-39161
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotectiv
价 格:¥电议型 号:T0825产 地:中国大陆