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T16704LQuilseconazole Formic acid(1340593-70-5 Free base);化合物 Quilseconazole Formic acid(1340593-70-5 Free
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
价 格:¥电议型 号:T16704L产 地:中国大陆
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T16286Nelonemdaz;化合物 NelonemdazSalfaprodil free base|||Neu2000;Salfaprodil free base|||Neu2000
Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke.
价 格:¥电议型 号:T16286产 地:中国大陆
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T16103ML-9 Free Base;化合物 T16103ML-9 Free Base
ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
价 格:¥电议型 号:T16103产 地:中国大陆
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T16090LMK-0773 FA;MK-0773 甲酸盐MK-0773 FA (606101-58-0 Free base);MK-0773 FA (606101-58-0 Free base)
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) is a selective androgen receptor modulator with an IC50 value of 6.6 nM for AR, which can be used for the prevention and treatment of cancer-related muscle wasting.
价 格:¥电议型 号:T16090L产 地:中国大陆
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T16083Mizagliflozin;化合物MizagliflozinGSK-1614235 free base|||KGA-3235 free base|||DSP-3235 free base;GSK-16
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
价 格:¥电议型 号:T16083产 地:中国大陆
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T15805LLY2510924 acetate(1088715-84-7 free base);化合物LY2510924 acetateLY2510924 acetate(1088715-84-7 free ba
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.
价 格:¥电议型 号:T15805L产 地:中国大陆
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T15760LLintopride HCl;Lintopride 盐酸盐Lintopride HCl(107429-63-0 Free base);Lintopride HCl(107429-63-0 Free b
Lintopride HCl is a 5HT-4 antagonist.
价 格:¥电议型 号:T15760L产 地:中国大陆
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T15595LIRL-1620 acetate;化合物IRL-1620 acetateIRL-1620 acetate(142569-99-1 free base);IRL-1620 acetate(142569-
IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
价 格:¥电议型 号:T15595L产 地:中国大陆
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T15561Imanixil;伊马昔尔HOE-402 free base;HOE-402 free base
Imanixil (HOE-402 free base) is an LDL receptor (LDLR) inducer, a hypolipidemic and hypocholesterolemic compound with antiatherogenic activity that inhibits the production of very low-density lipoproteins (VLDLs).Imanixil acts by stimulating the LDL receptor pathway.
价 格:¥电议型 号:T15561产 地:中国大陆
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T1552LItopride free base;化合物 T1552LHSR803|||HSR-803|||Itopride hydrochloride|||HSR 803;HSR803|||HSR-803|||
Itopride HCl is an AChE inhibitor and dopamine D2 receptor antagonist. It inhibits lower esophageal sphincter relaxation. It also used to treat functional dyspepsia and gastroesophageal reflux disease
价 格:¥电议型 号:T1552L产 地:中国大陆
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T15457LH-Lys-Trp-Lys-OH acetate;化合物 H-Lys-Trp-Lys-OH acetateH-Lys-Trp-Lys-OH acetate(38579-27-0 free base);
H-Lys-Trp-Lys-OH acetate is a peptide with antibacterial and antiviral activities.
价 格:¥电议型 号:T15457L产 地:中国大陆
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T15431Nemiralisib;奈米利塞GSK2269557 (free base)|||GSK2269557;GSK2269557 (free base)|||GSK2269557
Nemiralisib(GSK-2269557 free base) is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disease.
价 格:¥电议型 号:T15431产 地:中国大陆
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T15369Lgamma-DGG acetate(6729-55-1 free base);化合物gamma-DGG acetateγDGG|||γ-D-Glutamylglycine;γDGG|||γ-D-Glu
gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
价 格:¥电议型 号:T15369L产 地:中国大陆
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T15368LGalantide acetate;化合物Galantide醋酸盐Galantide acetate(138579-66-5 Free base);Galantide acetate(138579-6
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide acetate dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide acetate appears to bind to a single population of SP receptors (KD~40 nM).
价 格:¥电议型 号:T15368L产 地:中国大陆
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T15347FR167344 free base;化合物 T15347FR167344 free base
FR167344 free base is an orally active and nonpeptide antagonist of bradykinin receptor B2. FR167344 free base displays a high-affinity binding to the B2 receptor (IC50: 65 nM). It has no binding affinity for the B1 receptor.
价 格:¥电议型 号:T15347产 地:中国大陆
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T15259Evatanepag;化合物EvatanepagCP-533536 free acid;CP-533536 free acid|||2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing.
价 格:¥电议型 号:T15259产 地:中国大陆
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T15136LDiZPK Hydrochloride (1337883-32-5 free base);化合物 T15136LDiZPK Hydrochloride;DiZPK Hydrochloride
DiZPK Hydrochloride is a structural analog of pyrrolysine (Pyl), acting as a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.
价 格:¥电议型 号:T15136L产 地:中国大陆
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T15135LDirect Black 38 free acid;化合物 T15135LNSC8679|||Ferristatin II;NSC8679|||Ferristatin II
Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.
价 格:¥电议型 号:T15135L产 地:中国大陆
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T15025LCY5 triethylamine saltCY5三乙胺盐CY5 triethylamine salt(146368-11-8 Free base)
CY5 triethylamine salt is a water-soluble dye, Excitation (nm):649, Emission (nm): 670.
价 格:¥电议型 号:T15025L产 地:中国大陆
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T15019LCUR61414 hydrochloride;化合物CUR61414 hydrochlorideCUR61414 hydrochloride (334998-36-6 Free base);CU
CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM). CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively binds to smoothened (Smo, Ki= 44 nM). CUR61414 hydrochloride can induce cancer cells apoptosis without affecting neighboring non-tumor cells.
价 格:¥电议型 号:T15019L产 地:中国大陆