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T36067Bongkrekic acid;米酵菌酸Bongkrek Acid;Bongkrek Acid
Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia gladioli that inhibits adenine nucleotide translocase (ANT).Bongkrekic acid Bongkrekic acid Bongkrekic acid induces extracellular traps in neutrophils through signaling mediated by p38, ERK, PAD4, and P2X1.
价 格:¥电议型 号:T36067产 地:中国大陆
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T35930Ganglioside GM2 Mixture (sodium salt);Ganglioside GM2 Mixture (sodium salt)Ganglioside GM2 Mixture (
Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Levels of ganglioside GM2 are elevated in the brain of patients with Sandhoff disease, as well as feline and mouse models of the disease. Ganglioside GM2 accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2. Gan
价 格:¥电议型 号:T35930产 地:中国大陆
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T35834L(Sar?)-Angiotensin II acetate;化合物(Sar?)-Angiotensin II acetate(Sar?)-Angiotensin II acetate
(Sar?)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell growth in embryonic chick myocytes.
价 格:¥电议型 号:T35834L产 地:中国大陆
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T35834(Sar1)-Angiotensin II;(Sar?)-Angiotensin II(Sar?)-Angiotensin II;(Sar?)-Angiotensin II
The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
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T35809C20 Sphingomyelin (d18:1/20:0);C20 Sphingomyelin (d18:1/20:0)C20 Sphingomyelin (d18:1/20:0)
C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in m
价 格:¥电议型 号:T35809产 地:中国大陆
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T35806N-Stearoylsphingosine;N-硬脂酰神经鞘氨醇C(18:0)/C(18:1)|||Cer(d18:1/18:0)|||C18 Ceramide (d18:1/18:0)|||C18
N-Stearoylsphingosine (Cer(d18:1/18:0)) is an amide compound widely found in eukaryotic organisms that enhances protein phosphatase 2A (PP2A) activity by interfering with the binding of PP2A to PP2A inhibitor 2, leading to dephosphorylation of Akt.N-Stearoylsphingosine is used in prostate cancer research.
价 格:¥电议型 号:T35806产 地:中国大陆
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T35805C16 Sphingomyelin (d18:1/16:0);化合物 C16 Sphingomyelin (d18:1/16:0)Sphingomyelin 16:0|||N-Palmitoyl-D-
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.
价 格:¥电议型 号:T35805产 地:中国大陆
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T35803C14 Ceramide (d18:1/14:0);十四酰鞘氨醇Cer(d18:1/14:0)|||N-Myristoyl-D-sphingosine;Cer(d18:1/14:0)|||N-Myri
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson´s research.
价 格:¥电议型 号:T35803产 地:中国大陆
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T35781Sphinganine (d20:0);Sphinganine (d20:0)Sphinganine (d20:0);Sphinganine (d20:0)
Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well
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T35741Gliovirin;GliovirinGliovirin
Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease
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T3563Lvguidingan;化合物LvguidinganLvguidingan
Lvguidingan is an Anticonvulsant agent.
价 格:¥电议型 号:T3563产 地:中国大陆
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T35588Ganglioside GM3 Mixture (sodium salt);Ganglioside GM3 Mixture (sodium salt)Ganglioside GM3 Mixture (
Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functi
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T35587Ganglioside GD1a mixture (sodium salt);Ganglioside GD1a mixture (sodium salt)Ganglioside B1;Ganglios
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (T
价 格:¥电议型 号:T35587产 地:中国大陆
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T35553Ganglioside GQ1b Mixture (sodium salt);Ganglioside GQ1b Mixture (sodium salt)Ganglioside GQ1b Mixtur
Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes throu
价 格:¥电议型 号:T35553产 地:中国大陆
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T35552Ganglioside GD3 Mixture (sodium salt);Ganglioside GD3 Mixture (sodium salt)Ganglioside GD3 Mixture (
Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increa
价 格:¥电议型 号:T35552产 地:中国大陆
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T35239Yanangin;化合物 T35239Yanangine;Yanangine
Yanangin is a natural product found in Tiliacora. Yanangin is a novel and potent bioactive compound.
价 格:¥电议型 号:T35239产 地:中国大陆
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T35238Yanangcorinin;化合物 T35238Yanangcorinine;Yanangcorinine
Yanangcorinin is a biochemical.
价 格:¥电议型 号:T35238产 地:中国大陆
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T35058Vinglycinate;化合物 T35058Vinglicinato|||Vinglycinatum;Vinglicinato|||Vinglycinatum
Vinglycinate is a biochemical.
价 格:¥电议型 号:T35058产 地:中国大陆