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T14386AZD9567；化合物AZD9567Mizacorat；Mizacorat
AZD9567 is a potent and orally active and selective non-steroidal glucocorticoid receptor modulator (SGRM) with an IC50 value of 3.8 nM.It has demonstrated excellent efficacy in the Streptococcus cell wall (SCW) reactivation model of joint inflammation.
价 格：￥电议型 号：T14386产 地：中国大陆
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T1438Butoconazole nitrate；硝酸布康唑RS 35887；RS 35887|||硝酸布康唑
Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butoconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gra
价 格：￥电议型 号：T1438产 地：中国大陆
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T14378LAZD5582 acetate (1258392-53-8 free base)；化合物AZD5582 acetateAZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis.
价 格：￥电议型 号：T14378L产 地：中国大陆
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T14358Avoralstat；AVORALSTATBCX4161；BCX4161
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
价 格：￥电议型 号：T14358产 地：中国大陆
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T14357Spebrutinib besylate；化合物 T14357CC-292 (besylate)|||AVL-292 (benzenesulfonate)；CC-292 (besylate)|||AV
Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).
价 格：￥电议型 号：T14357产 地：中国大陆
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T14350Soblidotin；化合物SoblidotinAuristatin PE|||TZT-1027；Auristatin PE|||TZT-1027
Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.
价 格：￥电议型 号：T14350产 地：中国大陆
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T14349Auristatin F；澳瑞他汀 FAuristatin F
Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
价 格：￥电议型 号：T14349产 地：中国大陆
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T14348Auristatin E；澳瑞他汀EAuristatin E
Auristatin E, a cytotoxic tubulin modifier, disrupts cell division by inhibiting tubulin polymerisation. This compound demonstrates potent and selective antitumor activities, serving as an MMAE analog and cytotoxin in antibody-drug conjugates.
价 格：￥电议型 号：T14348产 地：中国大陆
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T14345Atropine methyl bromide；甲溴阿托品Methylatropine bromide；甲溴阿托品|||Methylatropine bromide
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic examination. Compared to atropine, it demonstrates reduced penetration into the central nervous system[1][2]. Its high polarity makes it particularly effective in relieving pyloric spasm in infants.
价 格：￥电议型 号：T14345产 地：中国大陆
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T14344Atrimustine；阿莫司汀KM2210|||Bestrabucil；阿莫司汀|||KM2210|||Bestrabucil
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate. It has the antitumor activity.
价 格：￥电议型 号：T14344产 地：中国大陆
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T14343Atreleuton；化合物 T14343ABT-761|||VIA-2291；ABT-761|||VIA-2291
Atreleuton (ABT-761) is a potent and selective inhibitor of leukotriene formation[1][2][3]. As a reversible and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor, Atreleuton (ABT-761) exhibits selectivity.
价 格：￥电议型 号：T14343产 地：中国大陆
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T14341ATN-224；四硫钼酸二胆碱Bis(choline)tetrathiomolybdate；四硫钼酸二胆碱|||Bis(choline)tetrathiomolybdate
ATN-224 (Bis(choline)tetrathiomolybdate) inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor.
价 格：￥电议型 号：T14341产 地：中国大陆
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T14340Atiratecan；化合物 T14340TP300；TP300
Atiratecan (TP300) is a prodrug of camptothecin analog CH0793076. Atiratecan shows antitumor activity against both breast cancer resistance protein (BCRP)-positive and -negative xenografts in mouse xenograft models[1]. Atiratecan does not inhibit acetylcholinesterase (AChE) activities.
价 格：￥电议型 号：T14340产 地：中国大陆
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T14339Athidathion；化合物 T14339GS-13006；GS-13006
Thiophos (GS-13006) is an insecticide, which is an organic phosphate ester.
价 格：￥电议型 号：T14339产 地：中国大陆
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T14338Atabecestat；化合物 T14338JNJ-54861911；JNJ-54861911
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer´s Disease treatment[1].
价 格：￥电议型 号：T14338产 地：中国大陆
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T14337Buloxibutid；化合物BuloxibutidAT2 receptor agonist C21；AT2 receptor agonist C21
Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and 10 μM for AT2 and AT1 receptors, respectively.
价 格：￥电议型 号：T14337产 地：中国大陆
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T14333Asoxime dichloride；化合物Asoxime dichlorideTert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate|||Asox
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response.
价 格：￥电议型 号：T14333产 地：中国大陆
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T14312Apratastat化合物 T14312Apratastat
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].
价 格：￥电议型 号：T14312产 地：中国大陆
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T14308APN-C3-NH-Boc；化合物 T14308tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate；tert-Butyl 3
APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14308产 地：中国大陆
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T14282Amuvatinib hydrochloride；化合物 T14282HPK 56 hydrochloride|||MP470 hydrochloride；HPK 56 hydrochloride||
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administred multi-targeted tyrosine kinase inhibitor that exhibits strong efficacy against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, while also acting as a suppressor of DNA repair by inhibiting the RAD51 protein, which is crucial for repairing DNA damage[1][2][3]. This dual mechanism contributes to its antineoplastic activity[4].
价 格：￥电议型 号：T14282产 地：中国大陆
