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T18069Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride;化合物 T18069Lenalidomide-propargyl-C2-amido-Ph-NH
Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound that features a cereblon (CRBN) ligand, functioning as an E3 ubiquitin ligase, along with a linker. It can be utilized to create the PROTAC MD-224[1].
价 格:¥电议型 号:T18069产 地:中国大陆
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T18053Ipatasertib-NH2;化合物 T18053RG7440-NH2|||GDC-0068-NH2;RG7440-NH2|||GDC-0068-NH2
Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 to degrade AKT[1].
价 格:¥电议型 号:T18053产 地:中国大陆
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T17866DSPE-PEG5-propargyl;化合物 T17866DSPE-PEG5-propargyl
DSPE-PEG5-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17866产 地:中国大陆
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T17700Bromoacetamide-PEG3-propargyl;化合物 T17700Bromoacetamide-PEG3-propargyl
Bromoacetamide-PEG3-propargyl is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17700产 地:中国大陆
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T17685Boc-NH-PEG9-propargyl;化合物 T17685Boc-NH-PEG9-propargyl
Boc-NH-PEG9-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17685产 地:中国大陆
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T17669Boc-NH-PEG12-propargyl;化合物 T17669Boc-NH-PEG12-propargyl
Boc-NH-PEG12-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17669产 地:中国大陆
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T17641Boc-aminooxy-amide-PEG4-propargyl;化合物 T17641Boc-aminooxy-amide-PEG4-propargyl
Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17641产 地:中国大陆
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T17634Bis-propargyl-PEG13;化合物 T17634Bis-propargyl-PEG13
Bis-propargyl-PEG13 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17634产 地:中国大陆
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T17633Bis-propargyl-PEG11;化合物 T17633Bis-propargyl-PEG11
Bis-propargyl-PEG11 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17633产 地:中国大陆
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T17632Bis-propargyl-O-PEG17;化合物 T17632Bis-propargyl-O-PEG17
Bis-propargyl-O-PEG17 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17632产 地:中国大陆
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T1762RGFP966;化合物RGFP 966RGFP 966;RGFP 966
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.
价 格:¥电议型 号:T1762产 地:中国大陆
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T17503Azido-PEG3-S-PEG4-propargyl;化合物 T17503Azido-PEG3-S-PEG4-propargyl
Azido-PEG3-S-PEG4-propargyl is a polyethylene glycol (PEG)-based linker that contains the azide group and propargyl functionality. This linker is designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17503产 地:中国大陆
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T17445Aminooxy-amido-PEG4-propargyl;化合物 T17445Aminooxy-amido-PEG4-propargyl
Aminooxy-amido-PEG4-propargyl is a 4-unit PEG ADC linker that is non-cleavable and specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17445产 地:中国大陆
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T17371Ald-Ph-amido-PEG4-propargyl;化合物 T17371Ald-benzyl-amide-PEG4-propargyl;Ald-benzyl-amide-PEG4-propargy
Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed in ADC synthesis[1].
价 格:¥电议型 号:T17371产 地:中国大陆
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T173181,1,1-Trifluoroethyl-PEG4-propargyl;化合物 T173181,1,1-Trifluoroethyl-PEG4-propargyl
1,1,1-Trifluoroethyl-PEG4-propargyl is a polyethylene glycol (PEG)-based PROTAC linker employed for the synthesis of PROTACs [1].
价 格:¥电议型 号:T17318产 地:中国大陆
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T173171,1,1-Trifluoroethyl-PEG2-propargyl;化合物 T173171,1,1-Trifluoroethyl-PEG2-propargyl
1,1,1-Trifluoroethyl-PEG2-propargyl is a polyethylene glycol (PEG) derivative designed specifically to serve as a PROTAC linker in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17317产 地:中国大陆
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T1731TAME hydrochlorideNA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐|||Tos-Arg-OMe HCl|||TOS-ARG-OME hydrochlo
TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.
价 格:¥电议型 号:T1731产 地:中国大陆
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T17258WRG-28;化合物WRG-28WRG-28
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM)
价 格:¥电议型 号:T17258产 地:中国大陆
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T17125Tos-PEG2-O-Propargyl;化合物 T17125Tos-PEG2-O-Propargyl
Tos-PEG2-O-Propargyl is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, commonly employed for the synthesis of Thalidomide-O-PEG2-propargyl[1].
价 格:¥电议型 号:T17125产 地:中国大陆
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T17029Tegobuvir;化合物TegobuvirGS-9190|||GS 333126;GS-9190|||GS 333126|||5-[[6-[2,4-双(三氟甲基)苯基]-3-哒嗪基]甲基]-2-(2
Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.
价 格:¥电议型 号:T17029产 地:中国大陆