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T12925Sitravatinib malate;化合物 T12925MGCD516 malate|||MG-516 malate;MGCD516 malate|||MG-516 malate
Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively.) , shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment.
价 格:¥电议型 号:T12925产 地:中国大陆
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T12922Sirtuin modulator 1;化合物Sirtuin modulator 1SRT3025 Hydrochloride;SRT3025 Hydrochloride
Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.
价 格:¥电议型 号:T12922产 地:中国大陆
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T12900LSetiptiline maleate马来酸司普替林MO-8282|||马来酸司普替林
Setiptiline maleate is an antagonist of serotonin receptor.
价 格:¥电议型 号:T12900L产 地:中国大陆
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T1290Oxiconazole nitrate;硝酸奥昔康唑Ro 13-8996;硝酸奥昔康唑|||Ro 13-8996
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole, like other azole antifungals, most likely inhibits the cytochrome P450-dependent demethylation of lanosterol. This prevents the synthesis of ergosterol which is a crucial component of fungal cell membrane. By disrupting fungal cell membrane synthesis and integrity, oxiconazole
价 格:¥电议型 号:T1290产 地:中国大陆
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T12896LShepherdin 79-87 acetate;化合物Shepherdin 79-87 acetateShepherdin 79-87 acetate (861224-28-4 free base)
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.
价 格:¥电议型 号:T12896L产 地:中国大陆
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T1289Fusidic acid sodium salt;夫西地酸钠Sodium fusidate|||Fusidate Sodium|||Fucidin|||SQ-16360;Sodium fusidate
Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
价 格:¥电议型 号:T1289产 地:中国大陆
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T12882LSetmelanotide Acetate(920014-72-8 free base);化合物Setmelanotide AcetateRM-493 Acetate|||IRC-022493 Ace
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
价 格:¥电议型 号:T12882L产 地:中国大陆
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T12880Semotiadil recemate fumarate;司莫地尔 (准外消旋体富马酸盐)Semotiadil recemate fumarate
Semotiadil recemate fumarate is the recemate of Semotiadil fumarate. Semotiadil fumarate is a novel antagonist of vasoselective Ca2+ channel.
价 格:¥电议型 号:T12880产 地:中国大陆
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T12879Sematilide;化合物 T12879CK-1752;CK-1752
Sematilide is a blocker of selective IKr channel.
价 格:¥电议型 号:T12879产 地:中国大陆
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T12866SCH 42495 racemate;化合物 T12866SCH 42495 (racemate);SCH 42495 (racemate)
SCH 42495 racemate is the racemate of SCH 42495. SCH 42495 is an orally active neutral inhibitor of metalloendopeptidase (NEP), with antihypertensive effect.
价 格:¥电议型 号:T12866产 地:中国大陆
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T12865SCH-23390 maleate;化合物SCH-23390 maleateR-(+)-SCH-23390 maleate;R-(+)-SCH-23390 maleate
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively).
价 格:¥电议型 号:T12865产 地:中国大陆
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T12851SB290157 trifluoroacetate;化合物SB290157 trifluoroacetateSB290157 trifluoroacetate
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
价 格:¥电议型 号:T12851产 地:中国大陆
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T12840Saterinone hydrochloride;化合物 T12840BDF 8634 hydrochloride;BDF 8634 hydrochloride
Saterinone hydrochloride is an inhibitor of phosphodiesterase III (PDE III).
价 格:¥电议型 号:T12840产 地:中国大陆
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T1284Megestrol acetate;醋酸甲地孕酮SC10363|||BDH1298;SC10363|||醋酸甲地孕酮|||BDH1298
Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.
价 格:¥电议型 号:T1284产 地:中国大陆
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T12821S1PR1 modulator 1;化合物S1PR1 modulator 1S1PR1 modulator 1
S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
价 格:¥电议型 号:T12821产 地:中国大陆
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T12792S-8510 phosphate;化合物 T12792SB-737552 phosphate;SB-737552 phosphate
S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).
价 格:¥电议型 号:T12792产 地:中国大陆
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T12768RP 73163 Racemate;化合物 T12768RP 73163 Racemate
RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potent inhibitor of ACAT, shows cholesterol lowering activity.
价 格:¥电议型 号:T12768产 地:中国大陆
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T1276Danofloxacin mesylate;甲磺酸达氟沙星CP 76136-27;甲磺酸达氟沙星|||CP 76136-27
Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.
价 格:¥电议型 号:T1276产 地:中国大陆
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T12759Rosuvastatin D6 Sodium;化合物 T12759Rosuvastatin D6 Sodium
Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
价 格:¥电议型 号:T12759产 地:中国大陆
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T12758LRo 25-6981 Maleate;化合物 T12758LRo 25-6981 Maleate
Ro 25-6981 Maleate is a potent and selective activity-dependent NMDA receptors blocker containing the NR2B subunit.(IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively).
价 格:¥电议型 号:T12758L产 地:中国大陆