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T13049LSynucleozid hydrochloride (502139-01-7 free base)；化合物 T13049LSynucleozid hydrochloride|||NSC 377363
Synucleozid hydrochloride is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.
价 格：￥电议型 号：T13049L产 地：中国大陆
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T13014LSTING agonist-3 trihydrochloride；化合物 T13014LSTING agonist-3 trihydrochloride (2138299-29-1 free base
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
价 格：￥电议型 号：T13014L产 地：中国大陆
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T13003SSR128129E free acid；化合物 T13003SSR free acid；SSR free acid
SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).
价 格：￥电议型 号：T13003产 地：中国大陆
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T12992SPR741 acetate；醋酸盐SPR741 acetate|||NAB741 acetate|||SPR741 acetate (1179330-52-9 free base)；SPR741 a
SPR741 acetate is a cationic peptide derived from polymyxin B. It exhibits antimicrobial activity against gram-negative bacteria by inhibiting severe gram-negative bacterial sensory by increasing the permeability of the outer membrane of gram-negative bacteria.SPR741 acetate is often used in conjunction with antibiotics for the treatment of a number of diseases.
价 格：￥电议型 号：T12992产 地：中国大陆
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T12945SNT-207858 free base；化合物 T12945SNT-207858 free base
SNT-207858 free base is a selective, blood brain barrier penetrating, potent and orally active antagonist of melanocortin-4 (MC-4) receptor(IC50 of 22 nM (binding) and 11 nM (function), on the MC-4 receptor).
价 格：￥电议型 号：T12945产 地：中国大陆
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T12942LSN50 acetate (213546-53-3 free base)；化合物SN50 acetateSN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.
价 格：￥电议型 号：T12942L产 地：中国大陆
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T12932SM-164 Hydrochloride (957135-43-2 free base)；化合物 T12932SM-164 Hydrochloride；SM-164 Hydrochloride
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.
价 格：￥电议型 号：T12932产 地：中国大陆
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T12923(Rac)-SIS3 free base；化合物 T12923(Rac)-SIS3 free base
SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
价 格：￥电议型 号：T12923产 地：中国大陆
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T12896LShepherdin 79-87 acetate；化合物Shepherdin 79-87 acetateShepherdin 79-87 acetate (861224-28-4 free base)
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.
价 格：￥电议型 号：T12896L产 地：中国大陆
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T12882LSetmelanotide Acetate(920014-72-8 free base)；化合物Setmelanotide AcetateRM-493 Acetate|||IRC-022493 Ace
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
价 格：￥电议型 号：T12882L产 地：中国大陆
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T12878Semaglutide TFA (910463-68-2 free base)；化合物 T12878Semaglutide TFA；Semaglutide TFA
Semaglutide TFA is a agonist of glucagon-like peptide-1 (GLP-1) receptor,with a potential for type 2 diabetes treatment.
价 格：￥电议型 号：T12878产 地：中国大陆
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T12807(S)-Nicardipine；化合物 T12807(S)-YC-93 free base；(S)-YC-93 free base
(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).
价 格：￥电议型 号：T12807产 地：中国大陆
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T12778RTI-13951-33 hydrochloride；化合物 T12778RTI-13951-33 hydrochloride (2244884-08-8 free base)；RTI-13951-3
RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist. RTI-13951-33 hydrochloride exhibited an EC 50 of 25 nM in vitro cAMP functional assay. RTI-13951-33 hydrochloride significantly reduces alcohol reinforcement and intake behaviors in rats [1].
价 格：￥电议型 号：T12778产 地：中国大陆
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T12765RPR107393 free base；化合物 T12765RPR107393 free base
RPR107393 free base is a selective inhibitor of squalene synthase(rat liver microsomal squalene synthase, with an IC50 of 0.8 nM).
价 格：￥电议型 号：T12765产 地：中国大陆
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T12738L1Rivanicline 2HCl；(E)-位变异烟碱盐酸盐Rivanicline 2HCl(15585-43-0 Free base)；Rivanicline 2HCl(15585-43-0 Free
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
价 格：￥电议型 号：T12738L1产 地：中国大陆
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T12737Riviciclib；化合物 T12737P276-00 (free base)；P276-00 (free base)
Riviciclib is a potent inhibitor of cyclin-dependent kinase (CDK)(CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively),with antitumor activity on cisplatin-resistant cells.
价 格：￥电议型 号：T12737产 地：中国大陆
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T12718RG7800 hydrochloride (1449598-06-4 free base)；化合物 T12718RO6885247 hydrochloride|||RG7800 hydrochlori
RG7800 hydrochloride is an orally active modulator of SMN2 splicing.
价 格：￥电议型 号：T12718产 地：中国大陆
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T12633(R)-Nicardipine；化合物 T12633(R)-YC-93 free base；(R)-YC-93 free base
(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).
价 格：￥电议型 号：T12633产 地：中国大陆
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T12585LPXS-5153A monohydrochloride；化合物 T12585LPXS-5153A monohydrochloride (2125956-82-1 free base)；PXS-5153
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride dose-dependently reduced LOXL2-mediated collagen oxidation and collagen crosslinking in vitro which may represent an innovative therapeutic approach for the treatment of fibrosis
价 格：￥电议型 号：T12585L产 地：中国大陆
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T12527LMavodelpar free acid hydrochloride；化合物Mavodelpar盐酸盐Mavodelpar free acid hydrochloride(942594-93-6 Fr
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.
价 格：￥电议型 号：T12527L产 地：中国大陆
