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T10407Gartisertib;化合物 T10407ATR inhibitor 2;ATR inhibitor 2
ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation (IC50: 8 nM).
价 格:¥电议型 号:T10407产 地:中国大陆
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T10406Tuvusertib;化合物TuvusertibM1774|||ATR inhibitor 1;M1774|||ATR inhibitor 1
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 ?Μ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
价 格:¥电议型 号:T10406产 地:中国大陆
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T10405ATPA;化合物 T10405ATPA
ATPA is a selective glutamate receptor GluR5 activator (EC50s: 0.66, 1.4, 9.5, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S721T), GluR5(S741M), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V)).
价 格:¥电议型 号:T10405产 地:中国大陆
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T10404ATP synthase inhibitor 1;化合物ATP synthase inhibitor 1ATP synthase inhibitor 1
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels.
价 格:¥电议型 号:T10404产 地:中国大陆
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T10403Atorvastatin ethyl ester;化合物 T10403Atorvastatin ethyl ester
Atorvastatin ethyl ester, a derivative of Atorvastatin, exhibits potent inhibition of 9-cis-RA-induced Gal4 reporter activity.
价 格:¥电议型 号:T10403产 地:中国大陆
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T10402Atorvastatin Epoxy Tetrahydrofuran Impurity;化合物 T10402Atorvastatin Epoxy Tetrahydrofuran Impurity
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor.
价 格:¥电议型 号:T10402产 地:中国大陆
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T10401Atorvastatin acetonide;化合物 T10401Atorvastatin acetonide
Atorvastatin acetonide is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
价 格:¥电议型 号:T10401产 地:中国大陆
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T10400Atorvastatin acetonide tert-butyl ester;化合物 T10400Atorvastatin acetonide tert-butyl ester
Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an HMG-CoA reductase inhibitor.
价 格:¥电议型 号:T10400产 地:中国大陆
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T10399Atorvastatin 3-Deoxyhept-2E-Enoic Acid;化合物 T10399(2E)-2,3-Dehydroxy Atorvastatin;(2E)-2,3-Dehydroxy
Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
价 格:¥电议型 号:T10399产 地:中国大陆
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T10398ATN-161;化合物 T10398ATN-161
ATN-161 is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases in a murine model.
价 格:¥电议型 号:T10398产 地:中国大陆
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T10397ATN-161 trifluoroacetate salt;化合物ATN-161 trifluoroacetate saltATN-161 TFA salt;ATN-161 TFA salt
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
价 格:¥电议型 号:T10397产 地:中国大陆
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T10396ATM Inhibitor-1;化合物 T10396ATM Inhibitor-1
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM).
价 格:¥电议型 号:T10396产 地:中国大陆
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T10395LATM-3507化合物 ATM-3507ATM3507|||ATM 3507
ATM-3507 is a protomyosin inhibitor with anticancer activity that inhibits human melanoma and can be used to study ovarian cancer.
价 格:¥电议型 号:T10395L产 地:中国大陆
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T10395ATM-3507 trihydrochloride (1861449-70-8 free base);化合物 T10395ATM-3507 trihydrochloride;ATM-3507 trih
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).
价 格:¥电议型 号:T10395产 地:中国大陆
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T10394LATB107 hydrochloride;化合物ATB107盐酸盐ATB107 hydrochloride(455325-51-6 Free base);ATB107 hydrochloride(45
ATB107 hydrochloride is a novel and potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.
价 格:¥电议型 号:T10394L产 地:中国大陆
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T10394ATB107;化合物 T10394ATB107
ATB107 is a potent and novel inhibitor of indole-3-glycerol phosphate synthase (IGPS, KD: 3 μM).
价 格:¥电议型 号:T10394产 地:中国大陆
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T10393AT-007;化合物AT-007AT-007
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.
价 格:¥电议型 号:T10393产 地:中国大陆
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T10391Aspirin Aluminum阿司匹林铝Aluminum diacetylsalicylate|||阿司匹林铝
Aspirin Aluminum is an intermolecular compound that can inhibit gastrointestinal mucosal disorders induced by NSAIDs.
价 格:¥电议型 号:T10391产 地:中国大陆
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T10390Asperphenamate;化合物AsperphenamateAsperphenamate
Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM. Asperphenamate shows an anticancer effect.
价 格:¥电议型 号:T10390产 地:中国大陆
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T10389LAspartyl-alanyl-diketopiperazine acetate;化合物T10389LDA-DKP|||Aspartyl-alanyl-diketopiperazine acetate
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.
价 格:¥电议型 号:T10389L产 地:中国大陆