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  • T75821TAT-Gap19 TFA；化合物 TAT-Gap19 TFATAT-Gap19 TFA

    TAT-Gap19 TFA, a Cx mimetic peptide and specific connexin43 hemichannel (Cx43 HC) inhibitor, does not inhibit the corresponding Cx43 gap junction channels (GJCs). It crosses the blood-brain barrier and has been shown to alleviate liver fibrosis in mice [1] [2] [3].

    价 格：￥电议型 号：T75821产 地：中国大陆

  • T75820Gap19 TFA；化合物 Gap19 TFAGap19 TFA

    Gap19 TFA is a selective and potent blocker of connexin 43 (Cx43) hemichannels, originating from nine amino acids within the Cx43 cytoplasmic loop (CL). It operates by hindering intramolecular interactions between the C-terminus (CT) and the CL, effectively inhibiting hemichannel activity without affecting GJ channels or Cx40/pannexin-1 hemichannels. This peptide offers protective benefits for the myocardium.

    价 格：￥电议型 号：T75820产 地：中国大陆

  • T7582tafamidis meglumine；他发米帝司甲葡胺Fx-1006A；Fx-1006A|||他发米帝司甲葡胺

    Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade

    价 格：￥电议型 号：T7582产 地：中国大陆

  • T75819M1145 TFA；化合物 M1145 TFAM1145 TFA

    M1145 TFA, a chimeric peptide, acts as a selective agonist for the galanin receptor type 2 (GAL2), demonstrating a binding affinity (K i ) of 6.55 nM. It exhibits significantly greater selectivity for GAL2, with over 90-fold and 76-fold higher affinity compared to GAL1 (K i = 587 nM) and GalR3 (K i = 497 nM), respectively. Additionally, M1145 TFA enhances galanin signal transduction mechanisms [1].

    价 格：￥电议型 号：T75819产 地：中国大陆

  • T75818Galanin (1-29)(rat, mouse) TFA；化合物 Galanin (1-29)(rat, mouse) TFAGalanin (1-29)(rat, mouse) TFA

    Galanin (1-29)(rat, mouse) TFA acts as a non-selective agonist for galanin receptors, exhibiting affinities (Kis) of 0.98 nM for GAL1, 1.48 nM for GAL2, and 1.47 nM for GAL3, respectively. It possesses an anticonvulsant effect [1] [2].

    价 格：￥电议型 号：T75818产 地：中国大陆

  • T75817M617 TFA；化合物 M617 TFAM617 TFA

    M617 TFA, a selective galanin receptor 1 (GAL1) agonist, exhibits dissociation constants (Kis) of 0.23 nM for GAL1 and 5.71 nM for GAL2. Through activation of GAL1, M617 TFA enhances GLUT4 expression and content in the cardiac muscle of type 2 diabetic rats [1] [2].

    价 格：￥电议型 号：T75817产 地：中国大陆

  • T75815WKYMVM-NH2 TFA；化合物 WKYMVM-NH2 TFAWKYMVM-NH2 TFA

    WKYMVM-NH2 TFA, a potent agonist for N-formyl peptide receptor (FPR1) and FPRL1/2, activates key leukocyte effector functions including chemotaxis, complement receptor-3 mobilization, and NADPH oxidase activation, as documented in references [1] [2] [3].

    价 格：￥电议型 号：T75815产 地：中国大陆

  • T75814WRW4 TFA；化合物 WRW4 TFAWRW4 TFA

    WRW4 TFA is a formyl peptide receptor-like 1 (FPRL1) antagonist that specifically prevents the binding of WKYMVm to FPRL1 with an inhibition concentration (IC50) of 0.23 μM. It uniquely blocks the rise in intracellular calcium triggered by FPRL1 agonists such as MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide [1].

    价 格：￥电议型 号：T75814产 地：中国大陆

  • T75813Ac9-25 TFA；化合物 Ac9-25 TFAAc9-25 TFA

    Ac9-25 TFA, an N-terminal peptide of Annexin I, functions as a formyl peptide receptor (FPR) agonist, activating neutrophil NADPH oxidase via FPR [1] [2].

    价 格：￥电议型 号：T75813产 地：中国大陆

  • T75812MMK1 TFA；化合物 MMK1 TFAMMK1 TFA

    MMK1 TFA is a potent, selective agonist for the human formyl peptide receptor like-1 (FPRL-1/FPR2), exhibiting EC50 values of <2 nM for FPRL-1 and >10,000 nM for FPR1. This compound acts as a powerful chemotactic and calcium-mobilizing agent, effectively activating phagocytic leukocytes. It significantly enhances the Pertussis Toxin-sensitive production of proinflammatory cytokines IL-1b and IL-6 by human monocytes. Additionally, MMK1 TFA has been demonstrated to exhibit anxiolytic-like activity

    价 格：￥电议型 号：T75812产 地：中国大陆

  • T75811PBP10 TFA；化合物 PBP10 TFAPBP10 TFA

    PBP10, a cell-permeable and selective gelsolin-derived peptide, inhibits formyl peptide receptor 2 (FPR2) over FPR1 [1]. This 10-amino acid (AA) peptide features a rhodamine conjugation at its N terminus, exhibiting bactericidal activity against both gram-positive and gram-negative bacteria while mitigating microbial-induced inflammatory effects [2].

    价 格：￥电议型 号：T75811产 地：中国大陆

  • T75810AKTide-2T TFA；化合物 AKTide-2T TFAAKTide-2T TFA

    AKTide-2T TFA, serving as an optimal in vitro substrate for AKT, demonstrates competitive inhibition of histone H2B phosphorylation with a Ki value of 12 nM. It effectively mimics the optimal phosphorylation sequence of Akt and acts as an inhibitory peptide, distinct from the wildtype AKTide due to the absence of Thr at the S22 position [1].

    价 格：￥电议型 号：T75810产 地：中国大陆

  • T7581voxelotor；化合物voxelotorGBT 440；GBT 440

    Voxelotor (GBT 440) is an inhibitor of sickle hemoglobin (HbS).

    价 格：￥电议型 号：T7581产 地：中国大陆

  • T758092B-(SP) (TFA)；化合物 2B-(SP) (TFA)2B-(SP) (TFA)

    2B-(SP) TFA, an eIF2B-based substrate, is efficiently phosphorylated by both α and β isoforms of Glycogen Synthase Kinase-3 (GSK-3) [1].

    价 格：￥电议型 号：T75809产 地：中国大陆

  • T75808Phospho-Glycogen Synthase Peptide-2(substrate) TFA；化合物 Phospho-Glycogen Synthase Peptide-2(substrate

    Phospho-Glycogen Synthase Peptide-2 (substrate) serves as a peptide substrate for glycogen synthase kinase-3 (GSK-3) and is utilized for the affinity purification of protein-serine kinases [1].

    价 格：￥电议型 号：T75808产 地：中国大陆

  • T75807Sarafotoxin S6a TFA；化合物 Sarafotoxin S6a TFASarafotoxin S6a TFA

    Sarafotoxin S6a TFA, an analogue of sarafotoxin, functions as an endothelin receptor agonist with an ET_A/ET_B selectivity profile akin to Endothelin-3. It demonstrates an EC_50 of 7.5 nM in stimulating the pig coronary artery [1].

    价 格：￥电议型 号：T75807产 地：中国大陆

  • T75806Lyn peptide inhibitor TFA；化合物 Lyn peptide inhibitor TFALyn peptide inhibitor TFA

    Lyn Peptide Inhibitor TFA is a powerful, cell-permeable inhibitor specifically targeting the Lyn-coupled IL-5 receptor signaling pathway, without affecting alternative signaling pathways. It effectively prevents Lyn activation and impedes the association between Lyn tyrosine kinase and the βc subunit of IL-3/GM-CSF/IL-5 receptors. This compound is utilized in the investigation of asthma, allergic reactions, and various eosinophilic conditions [1].

    价 格：￥电议型 号：T75806产 地：中国大陆

  • T75805Antisauvagine-30 TFA；化合物 Antisauvagine-30 TFAAntisauvagine-30 TFA

    Antisauvagine-30 TFA (aSvg-30 TFA), a potent peptidic antagonist specific to the CRF 2 receptor, demonstrates high selectivity and competitive interaction. It shows dissociation constants (Kd) of 1.4 nM for mCRFR2β and 150 nM for CRFR1, highlighting its efficacy [1] [2] [3] [4].

    价 格：￥电议型 号：T75805产 地：中国大陆

  • T75804K41498 TFA；化合物 K41498 TFAK41498 TFA

    K41498 TFA, an analog of antisauvagine-30 (aSvg-30), is a potent and highly selective antagonist of CRF2 receptors, exhibiting K i values of 0.66 nM, 0.62 nM, and 425 nM for human CRF 2α, CRF 2β, and CRF 1 receptors, respectively. This compound effectively inhibits sauvagine-stimulated cAMP accumulation in cells expressing hCRF 2α and hCRF 2β. It is utilized in studies investigating hypotension [1].

    价 格：￥电议型 号：T75804产 地：中国大陆

  • T75803FC131 TFA；化合物 FC131 TFAFC131 TFA

    FC131 TFA is a CXCR4 antagonist, inhibits [ 125 I]-SDF-1 binding to CXCR4 , with an IC 50 of 4.5 nM. Anti- HIV activity [1] .

    价 格：￥电议型 号：T75803产 地：中国大陆

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