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T11346LG3-C12 acetate(848301-94-0 free base);化合物G3-C12 acetateG3-C12 acetate(848301-94-0 free base)
G3-C12 acetate shows anticancer activity.?is a galectin-3 binding peptide, with Kd of 88 nM.
价 格:¥电议型 号:T11346L产 地:中国大陆
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T11342G-5555 hydrochloride (1648863-90-4 free base);化合物 T11342G-5555 hydrochloride;G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
价 格:¥电议型 号:T11342产 地:中国大陆
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T11327LFR 167653 free base;化合物 T11327LFR 167653 free base
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.
价 格:¥电议型 号:T11327L产 地:中国大陆
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T11323Frakefamide TFA (188196-22-7 free base);化合物 T11323Frakefamide TFA;Frakefamide TFA
Frakefamide is unable to penetrate the blood-brain-barrier and enter the central nervous system. Frakefamide TFA is a potent analgesic that acts as a peripheral active μ-selective receptor agonist.
价 格:¥电议型 号:T11323产 地:中国大陆
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T11321FR194738 free base;化合物FR194738 free baseFR194738 free base
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.?
价 格:¥电议型 号:T11321产 地:中国大陆
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T11319FR183998 free base;化合物FR183998FR183998 free base
FR183998 free base is an inhibitor of Na+/Ca2+ Exchanger.
价 格:¥电议型 号:T11319产 地:中国大陆
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T11316FOY 251 free base;化合物 T11316FOY 251 free base
FOY 251 free base acts as a proteinase inhibitor. FOY 251 free base is an anti-proteolytic active metabolite camostate.
价 格:¥电议型 号:T11316产 地:中国大陆
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T11290FK-448 Free base;化合物 T11290FK-448 Free base
FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.
价 格:¥电议型 号:T11290产 地:中国大陆
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T11282LFGTI-2734 mesylate (1247018-19-4 free base);化合物 T11282LFGTI-2734 mesylate;FGTI-2734 mesylate
FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates KRAS resistance by preventing its membrane localization, effectively impeding mutant KRAS patient-derived pancreatic tumors.
价 格:¥电议型 号:T11282L产 地:中国大陆
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T11237LCamizestrant TFA;Camizestrant三氟乙酸盐Camizestrant TFA(2222844-89-3 Free base)|||AZD-9833 TFA;Camizestra
Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).
价 格:¥电议型 号:T11237L产 地:中国大陆
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T11227L1Eravacycline HCl;盐酸伊拉瓦环素Eravacycline HCL(1207283-85-9 Free bse)|||TP-434 HCl;Eravacycline HCL(120728
Eravacycline HCl (TP-434 HCl) is potent antibiotic with broad-spectrum antibacterial activity.
价 格:¥电议型 号:T11227L1产 地:中国大陆
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T11220LUK 227786;化合物T11220Lhydrochloride(150452-18-9 Free base)|||1-[4-(1,3-Benzodioxol-5a-ylmethylamino)-6
UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.
价 格:¥电议型 号:T11220L产 地:中国大陆
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T11154LEG01377 2HCl;EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base);EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格:¥电议型 号:T11154L产 地:中国大陆
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T11128Dutogliptin;化合物 T11128PHX-1149 free base;PHX-1149 free base
Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T11128产 地:中国大陆
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T11119Duocarmycin DM free base;化合物 T11119Duocarmycin;Duocarmycin
Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.
价 格:¥电议型 号:T11119产 地:中国大陆
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T11095DREADD agonist 21 dihydrochloride;化合物 T11095DREADD agonist 21 dihydrochloride (56296-18-5 free base)
DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].
价 格:¥电议型 号:T11095产 地:中国大陆
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T11090L1Aldoxorubicin hydrochloride;化合物Aldoxorubicin盐酸盐Aldoxorubicin hydrochloride (1361644-26-9 Free base);
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
价 格:¥电议型 号:T11090L1产 地:中国大陆
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T11087DOV-216,303 Free Base;化合物DOV-216,303 Free BaseDOV-216303;DOV-216303
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
价 格:¥电议型 号:T11087产 地:中国大陆
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T11052LDisitertide acetate;地司特泰醋酸盐P144 acetate|||Disitertide acetate(272105-42-7 Free base);P144 acetate|||
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an apoptosis inducer.
价 格:¥电议型 号:T11052L产 地:中国大陆
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T11048LDIPQUO hydrochloride;化合物DIPQUO盐酸盐DIPQUO hydrochloride(1269365-82-3 Free base);DIPQUO hydrochloride(1
DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
价 格:¥电议型 号:T11048L产 地:中国大陆