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T11368GATA4-NKX2-5-IN-1；化合物GATA4-NKX2-5-IN-1GATA4-NKX2-5-IN-1
GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.GATA4-NKX2-5-IN-1 ?dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM.
价 格：￥电议型 号：T11368产 地：中国大陆
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T11358gamma-secretase modulator 1；化合物gamma-secretase modulator 1N-[3-methoxy-4-(4-methylimidazol-1-yl)phen
gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer´s disease.
价 格：￥电议型 号：T11358产 地：中国大陆
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T11353LGallopamil hydrochloride；化合物Gallopamil hydrochlorideMethoxyverapamil hydrochloride；Methoxyverapamil
Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.
价 格：￥电议型 号：T11353L产 地：中国大陆
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T11353Gallopamil；戈洛帕米Methoxyverapamil；Methoxyverapamil|||戈洛帕米
Gallopamil (Methoxyverapamil) inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist.
价 格：￥电议型 号：T11353产 地：中国大陆
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T11352Galidesivir triphosphate；化合物 T11352BCX4430-triphosphate|||Immucillin-A triphosphate|||BCX6870；BCX443
Galidesivir triphosphate is a substrate for viral RNA-dependent RNA polymerase (RDRP), resulting in termination of viral RNA replication and thus serves as an antiviral. Galidesivir triphosphate inhibits HCV NS5B RNA polymerase activity and protects mice against Ebola. Galidesivir triphosphate (Immucillin-A triphosphate) is converted by the prodrug Galidesivir.
价 格：￥电议型 号：T11352产 地：中国大陆
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T11351Galanthamine N-Oxide；加兰他明 N-氧化物Galanthamine N-Oxide
Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate accommodation within the active sites of Torpedo californica AChE (TcAChE), human AChE (hAChE), and human BChE (hBChE) enzymes.
价 格：￥电议型 号：T11351产 地：中国大陆
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T11341FXIa-IN-1；化合物 T11341FXIa-IN-1
FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.
价 格：￥电议型 号：T11341产 地：中国大陆
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T11318Dopexamine hydrochloride；盐酸多培沙明FPL60278AR；盐酸多培沙明|||FPL60278AR
Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow.
价 格：￥电议型 号：T11318产 地：中国大陆
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T11314Fosmanogepix；化合物 T11314APX001|||E1211；APX001|||E1211
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections.
价 格：￥电议型 号：T11314产 地：中国大陆
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T11313Forodesine hydrochloride化合物 T11313BCX-1777 hydrochloride|||Immucillin-H hydrochloride
Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.
价 格：￥电议型 号：T11313产 地：中国大陆
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T11311LFoliglurax；化合物 T11311LPXT002331；PXT002331
Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).
价 格：￥电议型 号：T11311L产 地：中国大陆
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T11311Foliglurax monohydrochloride；化合物 T11311PXT002331 (monohydrochloride)；PXT002331 (monohydrochloride)
Foliglurax monohydrochloride Antiparkinsonian effect. is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM.
价 格：￥电议型 号：T11311产 地：中国大陆
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T11307Fluxametamide化合物Fluxametamide4-[5-(3,5-二氯苯基)-4,5-二氢-5-(三氟甲基)-3- 异恶唑基]-N-[(甲氧基氨基)亚甲基]-2-甲基苯 甲酰胺
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls).
价 格：￥电议型 号：T11307产 地：中国大陆
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T11306Fluvastatin D6 sodium；化合物 T11306XU 62-320 (D6)；XU 62-320 (D6)
Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium.
价 格：￥电议型 号：T11306产 地：中国大陆
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T11303Fluorobexarotene；化合物FluorobexaroteneFluorobexarotene
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.?Fluorobexarotene ?is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor.?Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
价 格：￥电议型 号：T11303产 地：中国大陆
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T11302Flumexadol；化合物 T11302Flumexadol
Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A receptor. Flumexadol is an orally active non-narcotic analgesic.
价 格：￥电议型 号：T11302产 地：中国大陆
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T11301LFlomoxef sodium；氟氧头孢钠Flomoxef sodium
Flomoxef sodium, an antibiotic belonging to the oxacephem group, exhibits excellent activity against a broad spectrum of Gram-positive bacteria.
价 格：￥电议型 号：T11301L产 地：中国大陆
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T11301Flomoxef；氟氧头孢Flomoxef
Flomoxef is an antibiotic in oxacephem group and has excellent activity against various gram-positive bacteria.
价 格：￥电议型 号：T11301产 地：中国大陆
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T1128L(S)-Oxiracetam；化合物 T1128L(S)-ISF-2522|||S-Oxiracetam；(S)-ISF-2522|||S-Oxiracetam
(S)-Oxiracetam is a positive allosteric the AMPA receptorsmodulator.
价 格：￥电议型 号：T1128L产 地：中国大陆
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T11289Finafloxacin；非那沙星Finafloxacin
Finafloxacin, a fluoroquinolone antimicrobial agent from a new 8-cyano subclass, is most effective in slightly acidic environments (pH 5.0-6.0), a condition where other fluoroquinolones typically reduce in activity. It selectively targets bacterial type II topoisomerases, such as DNA gyrase and DNA topoisomerase IV, making it suitable for treating serious bacterial infections particularly in acidic contexts, including urinary tract infections (UTIs) and Helicobacter pylori infections.
价 格：￥电议型 号：T11289产 地：中国大陆
