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T62654Fluocortin butyl ester；化合物 Fluocortin butyl esterFluocortin butyl ester
Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when used topically. fluocortin butyl ester appears to be an effective, well-tolerated topical steroid that can be used in studies of perennial rhinitis.
价 格：￥电议型 号：T62654产 地：中国大陆
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T6252Ipatasertib；帕他色替GDC-0068|||RG7440；GDC-0068|||RG7440|||帕他色替
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
价 格：￥电议型 号：T6252产 地：中国大陆
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T62515SIRT2-IN-9；化合物SIRT2-IN-9SIRT2-IN-9
SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used for cancer research.
价 格：￥电议型 号：T62515产 地：中国大陆
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T62473Edecesertib；化合物 EdecesertibEdecesertib
Edecesertib (GS-5718) is a selective, orally active IRAK-4 inhibitor that exhibits anti-inflammatory activity. edecessertib can be used to study rheumatoid arthritis (RA) and lupus erythematosus (LE).
价 格：￥电议型 号：T62473产 地：中国大陆
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T6247Onvansertib；化合物NMS-P937NMS-P937|||NMS-1286937；NMS-P937|||NMS-1286937
Onvansertib (NMS-1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.
价 格：￥电议型 号：T6247产 地：中国大陆
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T62265(+)-Sparteine sulfate pentahydrate；化合物 (+)-Sparteine sulfate pentahydrate(+)-Sparteine sulfate penta
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.
价 格：￥电议型 号：T62265产 地：中国大陆
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T62240Sirt1/2-IN-1；化合物 Sirt1/2-IN-1Sirt1/2-IN-1
Sirt1/2-IN-1 (Compound 7) is an inhibitor of SIRT1 and SIRT2 and is capable of acting on SIRT1 (IC50: 1.81 μg/mL), SIRT2 (IC50: 2.10 μg/mL) and SIRT3 (IC50: 20.5 μg/mL) and has α-microtubulin hyperacetylation activity ( Sirt1/2-IN-1 exhibited significant anticancer effects.
价 格：￥电议型 号：T62240产 地：中国大陆
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T6219Azilsartan Medoxomil；阿齐沙坦酯TAK-491；TAK-491|||阿齐沙坦酯
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
价 格：￥电议型 号：T6219产 地：中国大陆
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T62186ART615；化合物 ART615ART615
ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).
价 格：￥电议型 号：T62186产 地：中国大陆
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T62083Camonsertib；化合物CamonsertibATR inhibitor 4|||RP-3500；ATR inhibitor 4|||RP-3500
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR (IC50: 120 nM) and is a more active inhibitor of ATM, DNA-PK and PI3Kα kinases. PK and PI3Kα kinases.
价 格：￥电议型 号：T62083产 地：中国大陆
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T62032SIRT5 inhibitor 2；化合物 SIRT5 inhibitor 2SIRT5 inhibitor 2
SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor (IC 50= 2.3 μM). SIRT5 inhibitor 2 shows inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 has research value in cancer and neurodegenerative diseases.
价 格：￥电议型 号：T62032产 地：中国大陆
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T61947SIRT5 inhibitor 3；化合物 SIRT5 inhibitor 3SIRT5 inhibitor 3
SIRT5 inhibitor 3 (compound 46) is an effective and competitive SIRT5 inhibitor (IC50=5.9 μ M). SIRT5 inhibitor 3 shows inhibitory effect on the deacetylation of SIRT5. SIRT5 inhibitor 3 has research value in cancer and neurodegenerative diseases.
价 格：￥电议型 号：T61947产 地：中国大陆
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T61725VU0463271 quarterhydrate；化合物 VU0463271 quarterhydrateVU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].
价 格：￥电议型 号：T61725产 地：中国大陆
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T6165Bardoxolone Methyl；甲基巴多索隆RTA 402|||CDDO Methyl ester|||TP-155|||NSC 713200；RTA 402|||CDDO Methyl est
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities.
价 格：￥电议型 号：T6165产 地：中国大陆
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T61627iMDK quarterhydrate；化合物 iMDK quarterhydrateiMDK quarterhydrate
iMDK quarterhydrate, a potent PI3K inhibitor, is effective in inhibiting the growth factor MDK (also known as midkine or MK) while demonstrating suppression of non-small cell lung cancer (NSCLC). In combination with a MEK inhibitor, iMDK quarterhydrate demonstrates cooperative inhibition of NSCLC without causing harm to normal cells and mice [1].
价 格：￥电议型 号：T61627产 地：中国大陆
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T6147Nortadalafil；去甲基他达那非Demethyl Tadalafil；Demethyl Tadalafil|||去甲基他达那非
Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
价 格：￥电议型 号：T6147产 地：中国大陆
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T61457SIRT5 inhibitor 4；化合物 SIRT5 inhibitor 4SIRT5 inhibitor 4
SIRT5 inhibitor 4 (compound 11) is a highly effective and selective inhibitor of SIRT5, with IC50 values of 26.4 μM and >400 μM for SIRT5 and other SIRT subtypes, respectively [1].
价 格：￥电议型 号：T61457产 地：中国大陆
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T6136Canertinib卡纽替尼PD-183805|||CI-1033|||卡纽替尼
Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
价 格：￥电议型 号：T6136产 地：中国大陆
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T6131Pimasertib；化合物PimasertibAS703026|||MSC1936369B|||SAR 245509；AS703026|||MSC1936369B|||N-[(2S)-2,3-二羟基
Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格：￥电议型 号：T6131产 地：中国大陆
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T6104Cerdulatinib hydrochloride；化合物Cerdulatinib hydrochlorideCerdulatinib|||PRT2070|||PRT062070 hydrochlo
Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
价 格：￥电议型 号：T6104产 地：中国大陆
