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T102009-Hydroxyellipticine hydrochloride;化合物 T102009-Hydroxyellipticine hydrochloride
9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. It exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride inihibits Hela S-3 and 293T cells (IC50s: 1.6 μM and 1.2μM).
价 格:¥电议型 号:T10200产 地:中国大陆
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T1020Doxorubicin hydrochloride;盐酸阿霉素Adriamycin|||Doxorubicin (Adriamycin) HCl|||Hydroxydaunorubicin hydro
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
价 格:¥电议型 号:T1020产 地:中国大陆
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T101988-M-PDOT;8-甲氧基-2-丙胺四氢萘8-Methoxy-2-propionamidotetralin|||AH-002;8-Methoxy-2-propionamidotetralin|||A
8-M-PDOT (AH-002) is a selective and potent melatonin MT2 receptor agonist that also inhibits MT1 receptors.8-M-PDOT has anxiolytic activity and may be used to study MT2-induced neuropathic pain.
价 格:¥电议型 号:T10198产 地:中国大陆
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T101978,?9-?Epoxy-?3-?isobutyryloxy-?10-?(2-?methylbutanoyl)?thymol;8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚8-9-epoxy
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro.
价 格:¥电议型 号:T10197产 地:中国大陆
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T101967α-Hydroxy-4-cholesten-3-one;化合物 T101967α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one is an intermediate in the synthesis of bile acids from cholesterol. It is a PXR agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss and other diseases associated with defective bile acid biosynthesis.It is the physiological substrate for CYP8B1.
价 格:¥电议型 号:T10196产 地:中国大陆
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T101957-O-Geranylscopoletin;化合物 T101957-Geranyloxy-6-methoxycoumarin;7-Geranyloxy-6-methoxycoumarin
7-O-Geranylscopoletin is a natural coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, antispasmodic, paralysis, hemiplegia, and stimulant.
价 格:¥电议型 号:T10195产 地:中国大陆
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T10191L7-Chlorokynurenic acid;7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA;7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格:¥电议型 号:T10191L产 地:中国大陆
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T101897-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene;化合物 T101897-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifen
7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist (IC50: 3.1 μM).
价 格:¥电议型 号:T10189产 地:中国大陆
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T101866-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-化合物 T101866-Quinoxalinecarboxylic-acid,-2,3-bis_b
6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-, derived from 2,3-Bis(bromomethyl)quinoxaline, displays antibacterial properties.
价 格:¥电议型 号:T10186产 地:中国大陆
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T101836-Methoxytricin;6-甲氧基哌啶6-Methoxytricin
6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells.
价 格:¥电议型 号:T10183产 地:中国大陆
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T101826-Hydroxybenzbromarone;6-羟基苯并溴马隆6-Hydroxybenzbromarone
6-Hydroxybenzbromarone is the major metabolite of Benzbromarone. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor (IC50: 21.5 μM). It is an angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting.
价 格:¥电议型 号:T10182产 地:中国大陆
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T101816-beta-Naloxol D5 hydrochloride;化合物 T101816β-Naloxol D5 hydrochloride;6β-Naloxol D5 hydrochloride
6-beta-Naloxol D5 hydrochloride is a deuterium-labeled opioid antagonist, closely related to naloxone, that serves as an effective compound in the field of chemical research.
价 格:¥电议型 号:T10181产 地:中国大陆
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T101806-Alpha Naloxol;化合物 T10180Alpha-Naloxol;Alpha-Naloxol
6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist and is a human metabolite of naloxone.
价 格:¥电议型 号:T10180产 地:中国大陆
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T101745-R-Rivaroxaban;5-R-利伐沙班5-R-Rivaroxaban
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0.4 nM).
价 格:¥电议型 号:T10174产 地:中国大陆
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T101715-Hydroxypyrazine-2-Carboxylic Acid;化合物 T101715-Hydroxypyrazine-2-Carboxylic Acid
5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.
价 格:¥电议型 号:T10171产 地:中国大陆
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T101645,6-Dihydroxyindole;5,6-二羟基吲哚Dopamine lutine;Dopamine lutine
5,6-Dihydroxyindole (Dopamine lutine) is a melanin precursor and has a broad-spectrum antibacterial, antiviral, antifungal, antiparasitic activity. It has cytotoxic effects and is strongly toxic against various pathogens.
价 格:¥电议型 号:T10164产 地:中国大陆
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T10157Regorafénib N-oxyde (M2)瑞戈非尼杂质 13瑞戈非尼杂质 13
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).
价 格:¥电议型 号:T10157产 地:中国大陆
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T101515-Lipoxygenase-In-1;化合物 T101515-Lipoxygenase-In-1
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.
价 格:¥电议型 号:T10151产 地:中国大陆
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T101494-Hydroxypropranolol-d7 hydrochloride;化合物 T10149(±)-4-hydroxy Propranolol D7 hydrochloride|||4-Hydro
4-Hydroxypropranolol D7 hydrochloride is deuterium-labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).
价 格:¥电议型 号:T10149产 地:中国大陆
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T101484-Hydroxynonenal;4-羟基壬烯醛4-HNE;4-羟基壬烯醛|||4-HNE
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
价 格:¥电议型 号:T10148产 地:中国大陆