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产品数:86101
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T6023Nutlin-3aNutlin-3a,Nutlin-3a chiral,(-)-Nutlin-3
Nutlin-3a, the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.
价 格:¥电议型 号:T6023产 地:美洲
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T8399Crizotinib hydrochloride;克里唑替尼盐酸PF-02341066 hydrochloride;克里唑替尼盐酸|||PF-02341066 hydrochloride
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)
价 格:¥电议型 号:T8399产 地:中国大陆
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T83023Antiproliferative agent-26;化合物 Antiproliferative agent-26Antiproliferative agent-26
Antiproliferative agent-26 (compound 4g) exhibits a broad spectrum of activity against leukemia, CNS cancers, melanoma, renal, and breast cancers at a concentration of 10 μM. It hinders colony formation and induces cell cycle arrest in the G1 phase at 5 μM, while arresting the cell cycle at the S phase at 25 μM [1].
价 格:¥电议型 号:T83023产 地:中国大陆
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T8219VU0238441;化合物VU0238441VU0238441
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
价 格:¥电议型 号:T8219产 地:中国大陆
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T82023Ivicentamab;化合物 IvicentamabGEN-3009;GEN-3009
Ivicentamab (GEN-3009), an IgG1κ humanized monoclonal antibody targeting CD37, is utilized in cancer research [1].
价 格:¥电议型 号:T82023产 地:中国大陆
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T81023Tegomil fumarate;化合物 Tegomil fumarateTegomil fumarate
Tegolimod fumarate is an immunomodulator [1].
价 格:¥电议型 号:T81023产 地:中国大陆
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T80918Tuparstobart;化合物 TuparstobartIncagn-02385;Incagn-02385
Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic cells [1].
价 格:¥电议型 号:T80918产 地:中国大陆
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T80589Zamerovimab;化合物 ZamerovimabSYN023|||CTB011;SYN023|||CTB011
Zamerovimab (CTB011; SYN023), a composite of human monoclonal antibodies CTB011 and CTB012, targets distinct, non-overlapping epitopes on the rabies virus (RABV) glycoprotein, with CTB011 specifically binding to antigenic site III. This compound is applicable in rabies research [1].
价 格:¥电议型 号:T80589产 地:中国大陆
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T80560Tulisokibart;化合物 TulisokibartPRA-023|||PRA023;PRA-023|||PRA023
Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody that targets TNFSF15/TL1A, with potential applications in researching various inflammatory and fibrotic diseases, including Crohn´s Disease (CD) [1] [2].
价 格:¥电议型 号:T80560产 地:中国大陆
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T80239TFLLRNPNDK-NH2;化合物 TFLLRNPNDK-NH2TFLLRNPNDK-NH2
TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP). As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the ´tethered ligand´ created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability, similar to thrombin´s effect.
价 格:¥电议型 号:T80239产 地:中国大陆
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T80238NODAGA-LM3 TFA;化合物 NODAGA-LM3 TFANODAGA-LM3 TFA
NODAGA-LM3 TFA, a SSTR2 antagonist, can be radiolabeled with ^68Ga for PET imaging applications, particularly in the visualization of SSTR-positive paragangliomas [1] [2].
价 格:¥电议型 号:T80238产 地:中国大陆
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T80237NODAGA-LM3;化合物 NODAGA-LM3NODAGA-LM3
NODAGA-LM3, when labeled with ^68Ga, serves as a PET imaging agent. As an SSTR2 antagonist, ^68Ga-NODAGA-LM3 is utilized for the visualization of SSTR-positive paragangliomas [1] [2].
价 格:¥电议型 号:T80237产 地:中国大陆
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T80236TFLLRN-NH2;化合物 TFLLRN-NH2TFLLRN-NH2
TFLLRN-NH2 is a biologically active peptide functioning as a PAR-1 agonist.
价 格:¥电议型 号:T80236产 地:中国大陆
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T80235YFLLRNP;化合物 YFLLRNPYFLLRNP
YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway. At low concentrations, YFLLRNP (60 μM) does not activate Gq or Gi pathways.
价 格:¥电议型 号:T80235产 地:中国大陆
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T80234SFNGGP-NH2;化合物 SFNGGP-NH2SFNGGP-NH2
SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor. Human cutaneous mast cells express PAR-3 mRNA, implicating a role in itch mechanotransduction, with both histamine-dependent and independent pathways reported. While PAR-3 alone does not induce itch, it may potentiate itch when co-expressed with PAR-4, enhancing thrombin´s action. This suggests that PAR-3´s primary function is not as a signal trans
价 格:¥电议型 号:T80234产 地:中国大陆
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T80233p53 CBS;化合物 p53 CBSp53 Consensus binding sequence;p53 Consensus binding sequence
p53 CBS (p53 Consensus binding sequence), a biologically active peptide, functions as the p53 consensus DNA binding site.
价 格:¥电议型 号:T80233产 地:中国大陆
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T80232Hrk BH3;化合物 Hrk BH3Hrk BH3
Hrk BH3, a biologically active peptide comprising the BH3 domain of Hrk, exhibits functionality within cellular processes.
价 格:¥电议型 号:T80232产 地:中国大陆
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T80231Bik BH3;化合物 Bik BH3Bik BH3
Bik BH3, a biologically active peptide derived from the BH3 domain of BIK, exhibits specific functions pertinent to its origin.
价 格:¥电议型 号:T80231产 地:中国大陆
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T80230μ-Conotoxin Sx IIIA;化合物 μ-Conotoxin Sx IIIAμ-Conotoxin Sx IIIA
μ-Conotoxin Sx IIIA is a biologically active peptide that functions as a blocker of NaV1.4 channels.
价 格:¥电议型 号:T80230产 地:中国大陆
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T80232,3,4-Trihydroxybenzoic acid;2,3,4-三羟基苯甲酸2,3,4-Trihydroxybenzoic acid
2,3,4-Trihydroxybenzoic acid is natural compound,with antioxidant activity
价 格:¥电议型 号:T8023产 地:中国大陆