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T11761Kinase inhibitor-1Kinase inhibitor-1
Kinase inhibitor-1 is a kinase inhibitor.
价 格:¥电议型 号:T11761产 地:美洲
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T11762LKira8Kira8,AMG-18,
Kira8 is a mono-selective IRE1α inhibitor. That allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).
价 格:¥电议型 号:T11762L产 地:美洲
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T11765KPLH1130KPLH1130
KPLH1130 improves glucose tolerance in HFD-fed mice.?KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses.?
价 格:¥电议型 号:T11765产 地:美洲
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T11766Eltanexor Z-isomerEltanexor Z-isomer,KPT-8602 (Z-isomer),
Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer ?is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.?
价 格:¥电议型 号:T11766产 地:美洲
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T11766LEltanexorEltanexor,KPT-8602,
Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines. Eltanexor is a second-generation, highly specific, and orally active exportin-1 (XP
价 格:¥电议型 号:T11766L产 地:美洲
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T13176TNO155TNO155
TNO155 is a potent selective and orally active allosteric wild-type SHP2 inhibitor with IC50 of 0.011 ?M,and has the potential for the study of RTK-dependent malignancies, especially advanced solid tumors.
价 格:¥电议型 号:T13176产 地:美洲
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T14176AleglitazarAleglitazar,R1439,RO0728804
Aleglitazar is being developed for the treatment of type II diabetes; It is currently in phase III clinical trials. In preliminary clinical studies, Aleglitazar has been demonstrated to improve hyperglycemia and dyslipidemia in patients with type 2 diabet
价 格:¥电议型 号:T14176产 地:美洲
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T15176DSS CrosslinkerDSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15176产 地:美洲
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T1761PD153035 hydrochloridePD153035 hydrochloride,AG 1517,SU 5271
PD153035 hydrochloride (ZM 252868; AG 1517) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
价 格:¥电议型 号:T1761产 地:美洲
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T1762RGFP 966RGFP 966
RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.
价 格:¥电议型 号:T1762产 地:美洲
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T1763SB525334SB525334
SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).
价 格:¥电议型 号:T1763产 地:美洲
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T1764SB203580SB203580,RWJ 64809,PB 203580
SB 203580 is a p38 MAPK inhibitor (IC50: 0.3-0.5 μM). It shows more than 100-fold selectivity over PKB, LCK, and GSK-3β.
价 格:¥电议型 号:T1764产 地:美洲
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T17649Boc-GABA-OHBoc-GABA-OH
Boc-GABA-OH is a PROTAC linker which can be used to synthesis UNC6852, an EED-targeted PROTAC[1].
价 格:¥电议型 号:T17649产 地:美洲
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T1765ErastinErastin
Erastin is a ferroptosis activator acting on mitochondrial VDAC. It induces ferroptotic cell death in vitro.
价 格:¥电议型 号:T1765产 地:美洲
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T17653Boc-NH-C4-acidBoc-NH-C4-acid
Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the?compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.
价 格:¥电议型 号:T17653产 地:美洲
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T17654Boc-NH-C6-BrBoc-NH-C6-Br
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1].
价 格:¥电议型 号:T17654产 地:美洲
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T1766EmpagliflozinEmpagliflozin,BI 10773,
Empagliflozin is a Sodium-Glucose Cotransporter 2 Inhibitor. The mechanism of action of empagliflozin is as a Sodium-Glucose Transporter 2 Inhibitor.
价 格:¥电议型 号:T1766产 地:美洲
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T1767BMH-21BMH-21,BMH21,BMH 21
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
价 格:¥电议型 号:T1767产 地:美洲