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T79470RORγt inverse agonist 31；化合物 RORγt inverse agonist 31RORγt inverse agonist 31
RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1].
价 格：￥电议型 号：T79470产 地：中国大陆
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T79464RORγ antagonist 1；化合物 RORγ antagonist 1RORγ antagonist 1
RORγ antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist to RORγ with a dissociation constant (K D) of 0.18 μM. It demonstrates anti-proliferative effects in the HPAF-II pancreatic cancer xenograft model, inhibits the RAS/MAPK and AKT/mTORC1 signaling pathways, and triggers caspase-dependent apoptosis in pancreatic cancer cells [1].
价 格：￥电议型 号：T79464产 地：中国大陆
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T79352RIPK2/3-IN-1；化合物 RIPK2/3-IN-1RIPK2/3-IN-1
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3. Additionally, in a 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay, RIPK2/3-IN-1 demonstrates an IC50 value of 14 ± 4 nM against RIPK2 [1].
价 格：￥电议型 号：T79352产 地：中国大陆
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T7912(?)-Myrtenal；(1R)-(-)-桃金娘烯醛(1R)-(?)-Myrtenal；(1R)-(-)-桃金娘烯醛|||桃金娘烯醛|||(1R)-(?)-Myrtenal
(?)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
价 格：￥电议型 号：T7912产 地：中国大陆
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T78954hNTS1R agonist-1；化合物 hNTS1R agonist-1hNTS1R agonist-1
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (BBB). It not only enhances motor function but also improves memory in a mouse model of Parkinson´s disease (PD). Additionally, this compound is an analog of Neurotensin(8-13) and demonstrates neuroprotective properties [1].
价 格：￥电议型 号：T78954产 地：中国大陆
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T78735D1R antagonist 1；化合物 D1R antagonist 1D1R antagonist 1
Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].
价 格：￥电议型 号：T78735产 地：中国大陆
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T78669(1R,4S)-Yimitasvir diphosphate；化合物 (1R,4S)-Yimitasvir diphosphate(1R,4S)-DAG-181 diphosphate|||(1R,4
Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A). It is utilized in the study of chronic hepatitis C virus infections [1].
价 格：￥电议型 号：T78669产 地：中国大陆
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T78265Anti-Mouse IL-1R Antibody (JAMA-147)；化合物 Anti-Mouse IL-1R Antibody (JAMA-147)Anti-Mouse IL-1R Antibo
Anti-Mouse IL-1R Antibody is an IgG2b subclass inhibitor targeting the mouse IL-1 receptor, sourced from Armenian hamsters.
价 格：￥电议型 号：T78265产 地：中国大陆
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T7820Raphin1；化合物Raphin1Raphin1
Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B).
价 格：￥电议型 号：T7820产 地：中国大陆
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T78105PAC1R antagonist 1；PAC1 拮抗剂1PAC1R antagonist 1
PAC1R antagonist 1 is an orally active PAC1 receptor antagonist that inhibits abnormal pain induced by pituitary adenylate cyclase-activating polypeptide (PACAP) and nerve damage, and may be used in the study of neoplasms and immune-related disorders.
价 格：￥电议型 号：T78105产 地：中国大陆
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T78087S1R agonist 2 hydrochloride；化合物 S1R agonist 2 hydrochlorideS1R agonist 2 hydrochloride
Compound 8b hydrochloride, a selective S1R agonist, exhibits affinity with K i s of 1.1 nM for S1R and 88 nM for S2R. It demonstrates neuroprotective effects against ROS and NMDA-induced neurotoxicity [1].
价 格：￥电议型 号：T78087产 地：中国大陆
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T78086S1R agonist 1 hydrochloride；化合物 S1R agonist 1 hydrochlorideS1R agonist 1 hydrochloride
S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values of 0.93 nM for S1R and 72 nM for S2R, and has demonstrated neuroprotective effects against ROS and NMDA-induced neurotoxicity [1].
价 格：￥电议型 号：T78086产 地：中国大陆
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T77802KRAS G12C inhibitor 1R；化合物 KRAS G12C inhibitor 1RKRAS G12C inhibitor 1R
KRAS G12C inhibitor 1R can be used in studies about Ras.
价 格：￥电议型 号：T77802产 地：中国大陆
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T77762ROS-generatingu00A0agentu00A01；ROS生成剂1ROS-generatingu00A0agentu00A01
Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.
价 格：￥电议型 号：T77762产 地：中国大陆
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T77750Rosmantuzumab；洛曼妥珠单抗OMP-131R10；OMP-131R10
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.
价 格：￥电议型 号：T77750产 地：中国大陆
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T77689(1R,2R)-(-)-1,2-Diaminocyclohexane；(1R,2R)-(-)-1,2-环己二胺(1R,2R)-Cyclohexane-1,2-diamin；(1R,2R)-Cycloh
(1R,2R)-(-)-1,2-Diaminocyclohexane ((1R,2R)-Cyclohexane-1,2-diamin) has anticancer and antitumor activity and can be used to study malignant tumors.
价 格：￥电议型 号：T77689产 地：中国大陆
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T77670(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxa
(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.
价 格：￥电议型 号：T77670产 地：中国大陆
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T77574ROS inducer 1；ROS诱导剂1ROS inducer 1
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actinidiae (Psa). ROS inducer 1 induces ROS production in Xanthomonas cells and can be used to study bacterial infections in crops.
价 格：￥电议型 号：T77574产 地：中国大陆
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T76670hMC1R agonist 1；化合物 hMC1R agonist 1hMC1R agonist 1
hMC1R agonist 1, with an EC 50 of 3 nM, exhibits at least 300-fold higher selectivity for hMC1R compared to hMC3R (EC 50 >902 nM), hMC4R (EC 50 >915 nM), and hMC5R (EC 50 >1000 nM). This compound demonstrates potential for therapeutic applications in targeting the melanocortin family [1].
价 格：￥电议型 号：T76670产 地：中国大陆
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T76640hMCH-1R antagonist 1；化合物 hMCH-1R antagonist 1hMCH-1R antagonist 1
HMCH-1R Antagonist 1 (Compound 30) serves as an effective and selective antagonist for the human melanin-concentrating hormone receptor 1 (hMCHR1), exhibiting a K_B value of 3.6 nM. It possesses the ability to bind to hMCHR1 and hMCHR2, with IC_50 values of 65 nM and 49 nM, respectively. This compound is applicable in metabolic research [1].
价 格：￥电议型 号：T76640产 地：中国大陆
