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T81161SHP2-IN-21;化合物 SHP2-IN-21SHP2-IN-21
SHP2-IN-21 (compound 208) is an inhibitor of SHP2, exhibiting an IC50 of 3 nM, and is utilized in glioblastoma research [1].
价 格:¥电议型 号:T81161产 地:中国大陆
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T81154SIRT1 activator 1;化合物 SIRT1 activator 1SIRT1 activator 1
SIRT1 Activator 1 (Compound 3), a marine-derived xyloallenoide A derivative from the Xylaria sp. mangrove fungus, exhibits angiogenic effects in zebrafish and protects human endothelial progenitor cells (hEPCs) from AngII-induced senescence. It achieves this by elevating SIRT1 expression and modulating the AMPK/Akt signaling pathway [1].
价 格:¥电议型 号:T81154产 地:中国大陆
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T81140SNM1A-IN-1;化合物 SNM1A-IN-1SNM1A-IN-1
SNM1A-IN-1 (compound 11a) serves as an inhibitor of the DNA damage repair enzyme SNM1A, exhibiting cytotoxic properties [1].
价 格:¥电议型 号:T81140产 地:中国大陆
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T81114Spns2-IN-1;化合物 Spns2-IN-1Spns2-IN-1
Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune response [1].
价 格:¥电议型 号:T81114产 地:中国大陆
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T81109Squalene synthase-IN-1;化合物 Squalene synthase-IN-1Squalene synthase-IN-1
Squalene synthase-IN-1 (compound 1) is a potent antihyperlipidemic agent that inhibits Squalene Synthase and demonstrates exceptional antioxidant and anti-inflammatory activities. It significantly reduces both glucose and oxidative stress levels without causing toxicity [1].
价 格:¥电议型 号:T81109产 地:中国大陆
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T81105SREBP/SCAP-IN-1;化合物 SREBP/SCAP-IN-1SREBP/SCAP-IN-1
SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].
价 格:¥电议型 号:T81105产 地:中国大陆
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T81101ST8154AA1;化合物 ST8154AA1ST8154AA1
ST8154AA1, an antibody-drug conjugate (ADC) component coupled with an HDAC inhibitor via a linker, exhibits antitumor activity [1].
价 格:¥电议型 号:T81101产 地:中国大陆
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T81100ST8155AA1;化合物 ST8155AA1ST8155AA1
ST8155AA1, a component of antibody-drug conjugates (ADCs), is tethered to an HDAC inhibitor via a linker and exhibits antitumor activity [1].
价 格:¥电议型 号:T81100产 地:中国大陆
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T8109d-Neomenthol;(1S,2S,5R)-(+)-新薄荷醇(1S,2S,5R)-2-Isopropyl-5-Methylcyclohexanol|||(+)-Neomenthol;(1S,2S,
d-Neomenthol ((+)-Neomenthol) is a natural product.
价 格:¥电议型 号:T8109产 地:中国大陆
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T80172Stromatoxin 1;化合物 Stromatoxin 1Stromatoxin 1
Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3. It selectively targets K(V)2.1 and K(V)2.2 channel subunits, which are crucial in counteracting myogenic and neurogenic contractions of rat urinary bladder smooth muscle (UBSM) [1].
价 格:¥电议型 号:T80172产 地:中国大陆
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T79903Sirtuin-1 inhibitor 1;Sirtuin-1 抑制剂1Sirtuin-1 inhibitor 1
Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.
价 格:¥电议型 号:T79903产 地:中国大陆
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T79871S6K2-IN-1;化合物 S6K2-IN-1S6K2-IN-1
S6K2-IN-1 (Compound 2) is an inhibitor of S6K2 with an IC50 of 22 nM and also exhibits inhibitory activity against FGFR4 with an IC50 of 216 nM. This compound demonstrates acceptable stability in mouse liver microsomes [1].
价 格:¥电议型 号:T79871产 地:中国大陆
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T79676SARS-CoV-2 3CLpro-IN-21;化合物 SARS-CoV-2 3CLpro-IN-21SARS-CoV-2 3CLpro-IN-21
SARS-CoV-2 3CLpro-IN-21 (Compound D6) is an irreversible, covalent inhibitor of SARS-CoV-2 3CL pro, demonstrating potent inhibition with an IC50 of 0.03 μM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 3CL pro with an IC50 of 0.12 μM [1].
价 格:¥电议型 号:T79676产 地:中国大陆
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T7959(+)-ISOPINOCAMPHEOL;(1S,2S,3S,5R)-(+)-异松蒎醇(+)-ISOPINOCAMPHEOL
(+)-ISOPINOCAMPHEOL is a natural product.
价 格:¥电议型 号:T7959产 地:中国大陆
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T79528SWS1;化合物 SWS1SWS1
SWS1, a d-(+)-biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating anti-tumor efficacy, as evidenced by a 66.1% tumor growth inhibition (TGI=66.1%) in the B16-F10 mouse model [1].
价 格:¥电议型 号:T79528产 地:中国大陆
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T79426SARS-CoV-2-IN-61;化合物 SARS-CoV-2-IN-61SARS-CoV-2-IN-61
SARS-CoV-2-IN-61 (compound 8i) is a potent inhibitor of the SARS-CoV-2 PLpro, exhibiting an IC50 of 16 ?M and demonstrating antiviral activities [1].
价 格:¥电议型 号:T79426产 地:中国大陆
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T7940Milnacipran ((1S-cis) hydrochloride);左旋米那普林Levomilnacipran Hydrochloride;左旋米那普林|||Levomilnacipran Hy
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
价 格:¥电议型 号:T7940产 地:中国大陆
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T79218SARS-CoV-2-IN-41;化合物 SARS-CoV-2-IN-41SARS-CoV-2-IN-41
SARS-CoV-2-IN-41 (compound 2) is a potent inhibitor of SARS-CoV-2 3CL protease, exhibiting an IC50 of 0.022 ?M and demonstrating antiviral efficacy [1].
价 格:¥电议型 号:T79218产 地:中国大陆
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T79207SUCNR1-IN-1;化合物 SUCNR1-IN-1SUCNR1-IN-1
SUCNR1-IN-1 (Compound 20) serves as a potent SUCNR1 inhibitor, exhibiting an IC50 of 88 nM against hSUCNR1. It is utilized in the study of rheumatoid arthritis, liver fibrosis, and obesity [1].
价 格:¥电议型 号:T79207产 地:中国大陆
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T79162SOS1/KRAS-IN-1;化合物 SOS1/KRAS-IN-1SOS1/KRAS-IN-1
SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].
价 格:¥电议型 号:T79162产 地:中国大陆