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T2084ETP46464ETP46464
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
价 格:¥电议型 号:T2084产 地:美洲
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T2087AF 353AF 353,Ro-4,
AF-353, an effective and orally bioavailable antagonist of the P2X3/P2X2/3 receptor, inhibits human and rat P2X3 (pIC50= 8.0).
价 格:¥电议型 号:T2087产 地:美洲
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T2088APD 668APD 668
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
价 格:¥电议型 号:T2088产 地:美洲
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T2109SD-208SD-208,SD208,SD 208
SD-208, a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.
价 格:¥电议型 号:T2109产 地:美洲
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T2208Zinc bacitracinZinc bacitracin,Bacitracin Zinc,Bacitracin zinc salt
Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).
价 格:¥电议型 号:T2208产 地:美洲
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T2300AZD1208AZD1208
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
价 格:¥电议型 号:T2300产 地:美洲
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T2480ApabetaloneApabetalone,RVX000222,RVX-208
RVX-208, an effective BET bromodomain inhibitor,has been investigated for the treatment of diabetes, atherosclerosis, and coronary artery disease.
价 格:¥电议型 号:T2480产 地:美洲
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T2500CediranibCediranib,AZD2171,NSC-732208
Cediranib (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit, selective more for VEGFR than PDGFR-α (36-
价 格:¥电议型 号:T2500产 地:美洲
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T4S20843’- Methoxy Puerarin3’- Methoxy Puerarin
3´-Methoxypuerarin shows neuron protection activity, it can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 3´-Methoxypuerarin has antioxidant activities, it shows ONOO(-) scavenging activity and weak NO· and O(2)(
价 格:¥电议型 号:T4S2084产 地:美洲
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T5208BAY-8002BAY-8002,BAY8002,BAY 8002
BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).
价 格:¥电议型 号:T5208产 地:美洲
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T5S2083Puerarin 6''-O-XylosidePuerarin 6''-O-Xyloside
Puerarin 6´´-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2.
价 格:¥电议型 号:T5S2083产 地:美洲
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T6208AS-252424AS-252424,AS252424,AS 252424
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
价 格:¥电议型 号:T6208产 地:美洲
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T6260AMG-208AMG-208,AMG208,AMG 208
AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
价 格:¥电议型 号:T6260产 地:美洲
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T83208Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside;化合物 Acacetin 7-O
Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (Compound 10), a flavone glycoside, is extractable from Robinia pseudoacacia leaf preparations [1].
价 格:¥电议型 号:T83208产 地:中国大陆
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T82379FN-A208 fusion peptide;化合物 FN-A208 fusion peptideFN-A208 fusion peptide
FN-A208 is an active peptide combining A208 from murine laminin a1 with the fibronectin active site GRGDS, linked by a glycine spacer. This compound self-assembles into amyloid-like fibrils and facilitates fibroblast cell adhesion through actin stress fiber formation, suggesting its use as a bioadhesive in tissue regeneration and engineering. FN-A208 targets IKVAV receptors and integrins, but its function can be inhibited by EDTA.
价 格:¥电议型 号:T82379产 地:中国大陆
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T82208Hexaarginine;化合物 HexaarginineHexaarginine
Hexa-arginine, a polycationic peptide composed of six arginine residues, efficiently penetrates cells and is primarily utilized for the intracellular delivery of low-molecular-weight agents, biomolecules, and particles [1].
价 格:¥电议型 号:T82208产 地:中国大陆
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T82089ICMT-IN-53;化合物 ICMT-IN-53ICMT-IN-53
ICMT-IN-53 (compound 12) is an ICMT inhibitor exhibiting an IC50 of 0.96 μM, alongside favorable PAMPA permeability and antiproliferative properties. It demonstrates efficacy by inhibiting the proliferation of MDA-MB-231 and PC3 cell lines with IC50 values of 5.14 μM and 5.88 μM, respectively [1].
价 格:¥电议型 号:T82089产 地:中国大陆
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T82088ICMT-IN-54;化合物 ICMT-IN-54ICMT-IN-54
ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by ICMT. It specifically inhibits the methylation of BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) in Saccharomyces cerevisiae expressing ICMT, marking an indirect inhibition of ICMT-mediated methylation [1].
价 格:¥电议型 号:T82088产 地:中国大陆
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T82087ICMT-IN-6;化合物 ICMT-IN-6ICMT-IN-6
ICMT-IN-6 (compound 29) serves as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an inhibitory concentration 50 (IC50) value of 0.09 μM [1].
价 格:¥电议型 号:T82087产 地:中国大陆