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  • T78277ATG-031；化合物 ATG-031ATG-031

    ATG-031 is a humanized monoclonal antibody targeting CD24 that promotes macrophage-mediated phagocytosis and induces cancer cell destruction by inhibiting the "don´t eat me" signals associated with various cancer growths. It is applicable for research into hematological malignancies and solid tumors.

    价 格：￥电议型 号：T78277产 地：中国大陆

  • T77277DSPE-alkyne；化合物 DSPE-alkyneDSPE-alkyne

    DSPE-alkyne is a phospholipid [1] .

    价 格：￥电议型 号：T77277产 地：中国大陆

  • T76277LVosoritide acetate；化合物 Vosoritide acetateVosoritide acetate

    Vosoritide acetate (BMN 111) is a natriuretic peptide receptor 2 (NPR2) agonist that promotes bone growth by influencing the proliferation and differentiation of chondrocytes [1].

    价 格：￥电议型 号：T76277L产 地：中国大陆

  • T76277Vosoritide；化合物 VosoritideVosoritide

    Vosoritide (BMN 111), a modified recombinant C-type natriuretic peptide (CNP) analogue, engages with natriuretic peptide receptor type B (NPR-B) to diminish the function of fibroblast growth factor receptor 3 (FGFR3). This compound is employed in the study of achondroplasia and dwarfism [1] [2] [3].

    价 格：￥电议型 号：T76277产 地：中国大陆

  • T75277Flucloxacillin；化合物 FlucloxacillinFlucloxacillin

    Flucloxacillin, an antibiotic, effectively combats both gram-positive and gram-negative bacteria [1] [2].

    价 格：￥电议型 号：T75277产 地：中国大陆

  • T74277NJH-2-056；NJH-2-056NJH-2-056

    NJH-2-056 is a deubiquitinase-targeting chimera (DUBTAC) linking the OTUB1 recruiter EN523 to the CFTR chaperone lumacaftor. NJH-2-056 can be used for cystic fibrosis research [1] .

    价 格：￥电议型 号：T74277产 地：中国大陆

  • T73277FABP-IN-2；化合物 FABP-IN-2FABP-IN-2

    FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.

    价 格：￥电议型 号：T73277产 地：中国大陆

  • T72777c-Met/HDAC-IN-3；化合物 c-Met/HDAC-IN-3c-Met/HDAC-IN-3

    c-Met/HDAC-IN-3, a dual inhibitor targeting both c-Met and HDAC, exhibits potent inhibitory activity with IC50 values of 12.50 nM for c-Met and 26.97 nM for HDAC1. It induces apoptosis and causes cell cycle arrest in the G2/M phase.

    价 格：￥电议型 号：T72777产 地：中国大陆

  • T72776NR2F1 agonist 1；化合物 NR2F1 agonist 1NR2F1 agonist 1

    NR2F1 agonist 1, a specific nuclear receptor NR2F1 activator, initiates dormancy programs in cancer cells by upregulating NR2F1 and its target genes controlling dormancy. This compound promotes neural crest-like features and suppresses growth in head and neck squamous cell carcinoma (HNSCC) through NR2F1 activation. Moreover, NR2F1 agonist 1 demonstrates tumor growth inhibition in a mouse primary tumor model.

    价 格：￥电议型 号：T72776产 地：中国大陆

  • T72774Ras modulator-1；化合物 Ras modulator-1Ras modulator-1

    Ras modulator-1 is a modulator of Ras.

    价 格：￥电议型 号：T72774产 地：中国大陆

  • T72772GPR81 agonist 2；化合物 GPR81 agonist 2GPR81 agonist 2

    GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 ?M for hGPR81 and 0.123 ?M for hGPR109A, respectively.

    价 格：￥电议型 号：T72772产 地：中国大陆

  • T72770p53 Activator 5；化合物 p53 Activator 5p53 Activator 5

    P53 Activator 5 is a potent activator of p53, exhibiting a SC150 value of less than 0.05 mM. It effectively binds to mutant p53, restoring its DNA-binding capability. Additionally, P53 Activator 5 demonstrates significant anti-tumor activity.

    价 格：￥电议型 号：T72770产 地：中国大陆

  • T7277SB 242084；化合物SB 242084 dihydrochloride hydrateSB 242084 dihydrochloride hydrate；6 - 氯-2,3 - 二氢- 5 -甲

    SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.

    价 格：￥电议型 号：T7277产 地：中国大陆

  • T72277CM-579 trihydrochloride；化合物 CM-579 trihydrochlorideCM-579 trihydrochloride

    CM-579 trihydrochloride, a first-in-class reversible, dual inhibitor of G9a and DNMT, exhibits potent in vitro cellular activity across a broad spectrum of cancer cells. It demonstrates inhibition with IC50 values of 16 nM for G9a and 32 nM for DNMT, respectively.

    价 格：￥电议型 号：T72277产 地：中国大陆

  • T71768CB10-277；化合物 CB10-277CB10-277

    CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups.

    价 格：￥电议型 号：T71768产 地：中国大陆

  • T7151GSK2982772；化合物GSK2982772GSK2982772

    GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.

    价 格：￥电议型 号：T7151产 地：中国大陆

  • T71355MDL-27788；化合物 MDL-27788MDL-27788

    MDL-27788 is a tricyclic inhibitor.

    价 格：￥电议型 号：T71355产 地：中国大陆

  • T71277Amiglumide；化合物 AmiglumideAmiglumide

    Amiglumide is a non-peptide cholecystokinin antagonist.

    价 格：￥电议型 号：T71277产 地：中国大陆

  • T70334SRI-31277；化合物 SRI-31277SRI-31277

    SRI-31277 is a TSP1-TGFβ inhibitor.

    价 格：￥电议型 号：T70334产 地：中国大陆

  • T70277Cynandione A；化合物 Cynandione ACynandione A

    Cynandione A, an acetophenone derived from Cynanchum wilfordii, has anti-inflammatory activity and significantly reduces pro-inflammatory cytokine overexpression via macrophage α7 nAChR activation and subsequent IL-10 expression.

    价 格：￥电议型 号：T70277产 地：中国大陆

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