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  • T76332Biotinyl-Glucagon (1-29), human, bovine, porcine;化合物 Biotinyl-Glucagon (1-29), human, bovine, porcin

    Biotinyl-Glucagon (1-29), encompassing human, bovine, and porcine versions, is a biotinylated form of glucagon. This peptide hormone, synthesized by the pancreas´s α-cells, elevates glucose and fatty acid levels in the bloodstream [1] [2].

    价 格:¥电议型 号:T76332产 地:中国大陆

  • T7598Calcium N5-methyltetrahydrofolate;N5-甲基四氢叶酸钙NSC173328;5-甲基四氢叶酸钙|||N5-甲基四氢叶酸钙|||NSC173328

    Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers

    价 格:¥电议型 号:T7598产 地:中国大陆

  • T753327-Hydroxy-4-methyl-2(1H)-quinolone;化合物 7-Hydroxy-4-methyl-2(1H)-quinolone7-Hydroxy-4-methyl-2(1H)-qu

    7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. For preservation, it should be protected from light.

    价 格:¥电议型 号:T75332产 地:中国大陆

  • T74332Rifasutenizol;化合物 RifasutenizolRifasutenizol

    Rifasutenizol (TNP-2198) is an orally bioavailable, dual-targeted antibacterial agent with potent effectiveness against both microaerophilic and anaerobic bacterial pathogens [1].

    价 格:¥电议型 号:T74332产 地:中国大陆

  • T73332BI-685509;化合物 BI-685509BI-685509

    BI-685509 is a potent and orally active sGC activator. BI-685509 restores cyclic guanosine monophosphate (cGMP) and improves functionality of nitric oxide (NO) pathways. BI-685509 can be used in research of chronic kidney disease (CKD) and diabetic kidney disease (DKD) [1] .

    价 格:¥电议型 号:T73332产 地:中国大陆

  • T73329MMV676584;化合物 MMV676584MMV676584

    MMV676584 has anti-tuberculosis avtivity. MMV676584 is a novel drug candidate for eumycetoma [1] .

    价 格:¥电议型 号:T73329产 地:中国大陆

  • T73328LP 218;化合物 P 218P 218

    P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.

    价 格:¥电议型 号:T73328L产 地:中国大陆

  • T73328DHFR-IN-5;化合物 DHFR-IN-5DHFR-IN-5

    DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.

    价 格:¥电议型 号:T73328产 地:中国大陆

  • T73327Merigolix;化合物 MerigolixMerigolix

    Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist [1] .

    价 格:¥电议型 号:T73327产 地:中国大陆

  • T73326CB2R-IN-3;化合物 CB2R-IN-3CB2R-IN-3

    CB2R-IN-3 is a selective antagonist of cannabinoid type 2 receptor (CB2R) . CB2R-IN-3 has high affinity for human CB2R and specific selectivity for CB1R. CB2R-IN-3 can be combined with CB65 , the activator of CB2R. CB2R-IN-3 effectively up-regulates the expression of anti-inflammatory cytokines and down-regulates the expression of pro-inflammatory cytokines [1] .

    价 格:¥电议型 号:T73326产 地:中国大陆

  • T73325MenA-IN-1;化合物 MenA-IN-1MenA-IN-1

    MenA IN-1, a potent inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB), exhibits an IC50 value of 13 ?M and a GIC50 value of 8 ?M, suggesting its potential utility in halting the ongoing proliferation of tuberculosis.

    价 格:¥电议型 号:T73325产 地:中国大陆

  • T73324PARL-IN-1;化合物 PARL-IN-1PARL-IN-1

    PARL-IN-1, a potent PARL inhibitor, exhibits an IC50 value of 28 nM. It effectively inhibits PARL, consequently robustly activating the PINK1/Parkin pathway and promoting PINK1/Parkin-dependent mitophagy.

    价 格:¥电议型 号:T73324产 地:中国大陆

  • T73323RdRP-IN-5;化合物 RdRP-IN-5RdRP-IN-5

    RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].

    价 格:¥电议型 号:T73323产 地:中国大陆

  • T73322TBK1-IN-1;TBK1 抑制剂 1TBK1-IN-1

    TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.

    价 格:¥电议型 号:T73322产 地:中国大陆

  • T73321CLK1-IN-2;化合物 CLK1-IN-2CLK1-IN-2

    CLK1-IN-2, a metabolically stable Clk1 inhibitor, exhibits selective activity for Clk1 with an IC50 value of 1.7 nM. It is applicable in researching tumor, Duchenne´s muscular dystrophy, and viral infections including HIV-1 and influenza.

    价 格:¥电议型 号:T73321产 地:中国大陆

  • T7332(E)-2-Decenoic acid;反式-2-癸烯酸trans-2-Decenoic acid;trans-2-Decenoic acid|||反式-2-癸烯酸

    (E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees.

    价 格:¥电议型 号:T7332产 地:中国大陆

  • T73225OTS193320;化合物 OTS193320OTS193320

    OTS193320, an imidazopyridine compound, acts as an inhibitor of SUV39H2 methyltransferase activity. It effectively reduces global histone H3 lysine 9 tri-methylation levels in breast cancer cells, promoting apoptotic cell death. When combined with Doxorubicin (DOX; HY-15142A), OTS193320 enhances the reduction of γ-H2AX levels and decreases cancer cell viability more significantly than when either agent is used alone.

    价 格:¥电议型 号:T73225产 地:中国大陆

  • T72507Palbociclib orotate;化合物 Palbociclib orotatePD 0332991 orotate;PD 0332991 orotate

    Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively. This compound demonstrates potent anti-proliferative effects and induces cell cycle arrest in cancer cells, applicable in research concerning HR-positive, HER2-negative breast cancer, and hepatocellular carcinoma [1] [3] [4].

    价 格:¥电议型 号:T72507产 地:中国大陆

  • T72247Ladostigil hydrochloride;化合物 Ladostigil hydrochlorideTV-3326 hydrochloride;TV-3326 hydrochloride

    Ladostigil hydrochloride (TV-3326), an orally active compound, acts as a dual inhibitor targeting both cholinesterase and brain-selective monoamine oxidase (MAO), demonstrating inhibition constants (IC50s) of 31.8 μM for acetylcholinesterase (AChE) and 37.1 μM for MAO-B. This compound exhibits neuroprotective, antioxidant, and anti-inflammatory properties, making it useful for research into depression and Alzheimer´s disease.

    价 格:¥电议型 号:T72247产 地:中国大陆

  • T71332NRC-2694 hydrochloride;化合物 NRC-2694 hydrochlorideNRC-2694 hydrochloride

    NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.

    价 格:¥电议型 号:T71332产 地:中国大陆

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