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T73902Desacetylcefotaxime;化合物 DesacetylcefotaximeDesacetylcefotaxime
Desacetylcefotaxime, an in vivo metabolite of Cefotaxime (CTX), exhibits noteworthy in vitro antimicrobial efficacy, akin to its parent compound, against a broad spectrum of aerobic and anaerobic bacteria [1].
价 格:¥电议型 号:T73902产 地:中国大陆
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T73900(±)-Alliin;化合物 (±)-Alliin(±)-Alliin
(±)-Alliin, the principal active component in garlic, functions as a potential inhibitor of SARS-CoV-2´s main protease (Mpro) [1].
价 格:¥电议型 号:T73900产 地:中国大陆
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T7390DMAT;2-二甲基氨基-4,5,6,7-四溴苯并咪唑Casein kinase II Inhibitor|||CK2 Inhibitor;Casein kinase II Inhibitor|||2
DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
价 格:¥电议型 号:T7390产 地:中国大陆
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T73432BAY-390;化合物 BAY-390BAY-390
BAY-390 is a brain-penetrating, species-agnostic inhibitor of TRPA1, exhibiting selective inhibition of human and rat TRPA1 with IC50 values of 16 nM for hTRPA1 FLIPR, 82 nM for hTRPA1 Ephys, 63 nM for rTRPA1 FLIPR, and 35 nM for rDRG Ephys. It holds potential for inflammation research applications.
价 格:¥电议型 号:T73432产 地:中国大陆
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T73390I-BET432;化合物 I-BET432I-BET432
I-BET432, a BET inhibitor, targets both the N-terminal (BD1) and C-terminal (BD2) bromodomains of BRD4, exhibiting pIC50 values of 7.5 and 7.2, respectively. As an orally administered candidate, I-BET432 holds potential for research in various oncology and inflammatory diseases.
价 格:¥电议型 号:T73390产 地:中国大陆
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T72390Estradiol hemihydrate;化合物 Estradiol hemihydrate17β-Oestradiol hemihydrate|||β-Estradiol hemihydrate
Estradiol (β-Estradiol) hemihydrate, a key female sex hormone and steroid, plays a significant role in up-regulating neural markers in human endometrial stem cells (hEnSCs) and facilitating their neural differentiation. It is also utilized in research focused on cancers, neurodegenerative diseases, and neural tissue engineering.
价 格:¥电议型 号:T72390产 地:中国大陆
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T71390AY 29315;化合物 AY 29315AY 29315
AY 29315 is a histamine H2-receptor antagonist with antisecretory and antiulcer activities.
价 格:¥电议型 号:T71390产 地:中国大陆
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T71353CCT239065;化合物 CCT239065CCT239065
CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600EBRAF and LCK inhibitor.
价 格:¥电议型 号:T71353产 地:中国大陆
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T70909AY 31390;化合物 AY 31390AY 31390
AY 31390 is a phosphodiesterase (PDE) inhibitor with antithrombotic activity.
价 格:¥电议型 号:T70909产 地:中国大陆
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T70390YM-543 choline;化合物 YM-543 cholineYM-543 choline
YM-543, also known as ASP-543, is a selective SGLT2 inhibitor. Sodium-glucose cotransporter 2 (SGLT2) is a specifically expressed transporter in the kidney that plays an important role in renal glucose reabsorption, and its inhibition may present a novel therapeutic strategy for treating diabetes. YM543 potently and selectively inhibited mouse and human SGLT2 activities at nanomolar ranges. In vivo single oral administration of YM543 dose-dependently and significantly reduced blood glucose level
价 格:¥电议型 号:T70390产 地:中国大陆
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T70038MJN68390;化合物 MJN68390MJN68390
MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.
价 格:¥电议型 号:T70038产 地:中国大陆
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T6976SB 239063;化合物SB239063SB239063;SB239063
SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.
价 格:¥电议型 号:T6976产 地:中国大陆
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T69390T-0902611 benzenesulfonate;化合物 T-0902611 benzenesulfonateT-0902611 benzenesulfonate
T-0902611 benzenesulfonate is a cytomegalovirus replication inhibitor that may be useful in the treatment of cytomegalovirus infections.
价 格:¥电议型 号:T69390产 地:中国大陆
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T68826A33903;化合物 A33903A33903
A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus. This molecule was moderately active and demonstrated good pharmacokinetic properties.
价 格:¥电议型 号:T68826产 地:中国大陆
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T68390Nivocasan;化合物 NivocasanNivocasan
Nivocasan, also known as GS-9450 and LB-84451, a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. GS-9450 treatment induced significant reductions in ALT levels in NASH patients.
价 格:¥电议型 号:T68390产 地:中国大陆
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T6826Emricasan;恩利卡生PF 03491390|||IDN-6556;PF 03491390|||恩利卡生|||IDN-6556
Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan also inhibits Zika virus infections.
价 格:¥电议型 号:T6826产 地:中国大陆
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T68195SC 39070;化合物 SC 39070SC 39070
SC 39070 is a leukotriene D4 antagonist.
价 格:¥电议型 号:T68195产 地:中国大陆
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T663904-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide;化合物T663904-(4-Amino-3-fluorophenoxy)-N-methylpicoli
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
价 格:¥电议型 号:T66390产 地:中国大陆
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T65390Fluvoxketone;化合物 FluvoxketoneFluvoxketone
Fluvoxketone is trifluoromethyl-substituted aryl ketone compound useful as an intermediate in the synthesis of Fluvoxamine, which is a selective serotonin reuptake inhibitor. In the synthesis of Fluvoxamine, the ketone carbonyl of Fluvoxketone is elaborated to an oxime.In vitro,the inhibitory effect of fluvoxamine on actin polymerization was concentration dependent, and its IC50 was approximately 30 μM.In vivo,fluvoxamine treated EAE rats showed a decrease in IFN-γ serum levels and an increase i
价 格:¥电议型 号:T65390产 地:中国大陆