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T75252Gemcitabine triphosphate;化合物 Gemcitabine triphosphateGemcitabine triphosphate
Gemcitabine triphosphate (dFdCTP), alongside its counterpart, the active diphosphate (dFdCDP), represents one of the two primary nucleoside metabolites of Gemcitabine within cellular structures. It serves as a benchmark in radiolabeled probe imaging investigations aimed at pinpointing tumors responsive to Gemcitabine. Furthermore, it is instrumental in assessing the compound´s absorption and retention by cells [1] [2].
价 格:¥电议型 号:T75252产 地:中国大陆
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T75251Firsocostat (S enantiomer);Firsocostat (S enantiomer)Firsocostat (S enantiomer)
Firsocostat S enantiomer (ND-630 S enantiomer) is the less active S enantiomer of Firsocostat. Firsocostat is an acetyl-CoA carboxylase ( ACC ) inhibitor.
价 格:¥电议型 号:T75251产 地:中国大陆
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T75250(R)-Funapide;化合物 (R)-Funapide(R)-Funapide
(R)-Funapide ((R)-TV 45070), the less active R-enantiomer of Funapide, acts as a potent Nav1.7 sodium channel blocker, primarily utilized in pain research [1].
价 格:¥电议型 号:T75250产 地:中国大陆
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T7525Didox;3,4-二羟基苯甲羟肟酸NSC-324360;3,4-二羟基苯甲羟肟酸|||NSC-324360
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia.
价 格:¥电议型 号:T7525产 地:中国大陆
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T74525PROTAC EGFR degrader 6;化合物 PROTAC EGFR degrader 6PROTAC EGFR degrader 6
PROTAC EGFR degrader 6 is a potent PROTAC EGFR degrader that effectively reduces EGFR Del19 levels in HCC827 cells, exhibiting a DC50 of 45.2 nM. It notably promotes apoptosis and induces G1 phase arrest in HCC827 cells [1].
价 格:¥电议型 号:T74525产 地:中国大陆
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T73525ML202;化合物 ML202ML202
ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), enhancing the cooperativity of phosphoenolpyruvate (PEP) binding, with negligible effect on adenosine diphosphate (ADP) binding.
价 格:¥电议型 号:T73525产 地:中国大陆
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T72525Antitumor agent-48;化合物 Antitumor agent-48Antitumor agent-48
Antitumor agent-48 is a 2,3-dehydrosilybin derivative with an antitumor activity. Antitumor agent-48 shows cytotoxic activity against MCF-7, NCI-H1299, HepG2 and HT29 cells with IC 50 values of 8.06 ?M, 13.1 ?M, 16.51 ?M and 12.44??M, respectively [1] .
价 格:¥电议型 号:T72525产 地:中国大陆
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T71525AB05831;化合物 AB05831AB05831
AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis of terminal, non-reducing N-acetyl-|3-D-glucosamine (GlcNAc) andN-acetyl-(3-D-galactosamine (GalNAc) residues in glycoproteins, gan-gliosides, and glycosaminoglycans (GAGs). HEX, released by chondrocytes into the extracellular compartment, promotes cartilage matrix degradation.
价 格:¥电议型 号:T71525产 地:中国大陆
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T6S15253,4-Dicaffeoylquinic acid;异绿原酸BIsochlorogenic acid B;Isochlorogenic acid B|||金银花|||异绿原酸B
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
价 格:¥电议型 号:T6S1525产 地:中国大陆
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T6S0525Farrerol;杜鹃素Farrerol
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced
价 格:¥电议型 号:T6S0525产 地:中国大陆
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T69525MIF degrader MD13;化合物 MIF degrader MD13MIF degrader MD13
MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF tautomerase active siteMIF degrader MD13. MD13 also exhibits antiproliferative effect in a 3D tumor spheroid model. In conclusion, we describe the first MIF-directed PROTAC (MD13) as a research tool, which also demonstrates the potential of PROTACs in cancer therapy.
价 格:¥电议型 号:T69525产 地:中国大陆
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T69488CB5255829;化合物 CB5255829CB5255829
CB5255829 is a novel inhibitor of Mycobacterium marinum MelF (Rv1936), exhibiting bacteriostatic/bactericidal activity against M. marinum and M. tuberculosis in vitro.
价 格:¥电议型 号:T69488产 地:中国大陆
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T68621LY 135252;化合物 LY 135252LY 135252
LY 135252 has potential as an antidepressant from being a specific inhibitor of norepinephrine uptake.
价 格:¥电议型 号:T68621产 地:中国大陆
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T68525Nafarelin acetate hydrate;化合物 Nafarelin acetate hydrateNafarelin acetate hydrate
Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analog of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estrogen/progesterone. When administered, Nafarelin has the purpose of causing increase estrogen that will negatively feed back upon hypothalamus to decrease GnRH ( negative feedback loop ) Through negative feedback, Nafarelin causes a decrease in pituitary secretion of gonadotropins lu
价 格:¥电议型 号:T68525产 地:中国大陆
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T67525N-(tert-Butoxycarbonyl)-N-methylglycine;化合物 N-(tert-Butoxycarbonyl)-N-methylglycineN-(tert-Butoxycar
N-(tert-Butoxycarbonyl)-N-methylglycine is a useful organic compound for research related to life sciences. The catalog number is T67525 and the CAS number is 13734-36-6.
价 格:¥电议型 号:T67525产 地:中国大陆
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T665252-(Piperidin-4-yl)-1H-benzo[d]imidazole;化合物 2-(Piperidin-4-yl)-1H-benzo[d]imidazole2-(Piperidin-4-yl
2-(Piperidin-4-yl)-1H-benzo[d]imidazole is a useful organic compound for research related to life sciences. The catalog number is T66525 and the CAS number is 38385-95-4.
价 格:¥电议型 号:T66525产 地:中国大陆
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T65525Fmoc-D-Lys-OH;化合物 Fmoc-D-Lys-OHFmoc-D-Lys-OH
Fmoc-D-Lys-OH is a useful organic compound for research related to life sciences. The catalog number is T65525 and the CAS number is 110990-08-4.
价 格:¥电议型 号:T65525产 地:中国大陆
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T65259Isobutyl cinnamate;化合物 Isobutyl cinnamateIsobutyl cinnamate
Isobutyl cinnamate is a useful organic compound for research related to life sciences. The catalog number is T65259 and the CAS number is 122-67-8.
价 格:¥电议型 号:T65259产 地:中国大陆
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T65258N-(tert-Butoxycarbonyl)-N-methyl-L-valine;化合物 N-(tert-Butoxycarbonyl)-N-methyl-L-valineN-(tert-Butox
N-(tert-Butoxycarbonyl)-N-methyl-L-valine is a useful organic compound for research related to life sciences. The catalog number is T65258 and the CAS number is 45170-31-8.
价 格:¥电议型 号:T65258产 地:中国大陆
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T65257Isobornyl methacrylate;化合物 Isobornyl methacrylateIsobornyl methacrylate
Isobornyl methacrylate is a useful organic compound for research related to life sciences. The catalog number is T65257 and the CAS number is 7534-94-3.
价 格:¥电议型 号:T65257产 地:中国大陆