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T77526Pim-1 kinase inhibitor 4;Pim-1 激酶 抑制剂4Pim-1 kinase inhibitor 4
Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and potential anticancer activity, and inhibits DPPH.Pim-1 kinase inhibitor 4 promotes apoptosis and inhibits the growth of PC-3 cells with an IC50 value of 16 nM. Pim-1 kinase inhibitor 4 promotes apoptosis and inhibits PC-3 cell growth with an IC50 of 16 nM. Pim-1 kinase inhibitor 4 can be used in prostate cancer research.
价 格:¥电议型 号:T77526产 地:中国大陆
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T76526Ac-D-DGla-LI-Cha-C;化合物 Ac-D-DGla-LI-Cha-CAc-D-DGla-LI-Cha-C
Ac-D-DGla-LI-Cha-C is a potent peptide inhibitor of the HCV protease, applicable in research targeting a range of diseases, including cancer, autoimmune, fibrotic, inflammatory, neurodegenerative, infectious, lung, heart and vascular, and metabolic diseases [1].
价 格:¥电议型 号:T76526产 地:中国大陆
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T75526Chlorfortunone A;化合物 Chlorfortunone AChlorfortunone A
Chlorfortunone A, a novel sesquiterpenoid dimer isolated from the roots of Chloranthus fortunei, inhibits transforming growth factor (TGF)-β activity [1].
价 格:¥电议型 号:T75526产 地:中国大陆
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T75269DMT-5Me-dC(Bz)-CE Phosphoramidite;化合物 DMT-5Me-dC(Bz)-CE PhosphoramiditeDMT-5Me-dC(Bz)-CE Phosphorami
DMT-5Me-dC(Bz)-CE Phosphoramidite is utilized in synthesizing locked nucleic acids (LNAs) to enhance fluorescent oligonucleotide probes by optimizing their spectral properties and target affinity [1].
价 格:¥电议型 号:T75269产 地:中国大陆
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T7526884-B10;化合物 84-B1084-B10
84-B10, a derivative of 3-phenylglutaric acid, inhibits cisplatin-induced tubular ferroptosis, attenuates mitochondrial damage and oxidative stress, and ameliorates acute kidney injury (AKI) resulting from cisplatin administration [1].
价 格:¥电议型 号:T75268产 地:中国大陆
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T75267Crocetin meglumine;化合物 Crocetin meglumineCrocetin meglumine
Crocetin (Transcrocetin) meglumine, sourced from Crocus sativus L. (saffron), functions as a high-affinity antagonist of the NMDA receptor.
价 格:¥电议型 号:T75267产 地:中国大陆
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T75263UK-2A;化合物 UK-2AUK-2A
UK-2A (Antibiotic UK 2A), a potent antifungal antibiotic, demonstrates significant antifungal activity [1] [2].
价 格:¥电议型 号:T75263产 地:中国大陆
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T75262Relamorelin TFA;化合物 Relamorelin TFARelamorelin TFA
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, acts as a potent and selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR), with a K_i of 0.42 nM for the GHS-1a receptor. This compound is capable of crossing the blood-brain barrier and effectively increases growth hormone levels while promoting faster gastric emptying. It holds significant research potential for conditions such as cachexia, gastroparesis, and disorders related to gastric/intestinal motility [1] [
价 格:¥电议型 号:T75262产 地:中国大陆
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T75261EGFR-IN-1 TFA;EGFR-IN-1 TFAEGFR-IN-1 TFA
EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 TFA potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR . EGFR-IN-1 TFA displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity [1] .
价 格:¥电议型 号:T75261产 地:中国大陆
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T7526JNJ-17203212;化合物JNJ-17203212JNJ-17203212
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).
价 格:¥电议型 号:T7526产 地:中国大陆
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T74526Antifungal agent 29;化合物 Antifungal agent 29Antifungal agent 29
Antifungal Agent 29 (compound 9d) is a potent, selective, and non-toxic agent effective against Cryptococcus neoformans, exhibiting an MIC of ≤0.23 μM [1].
价 格:¥电议型 号:T74526产 地:中国大陆
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T73526M5N36;化合物 M5N36M5N36
M5N36, a potent and selective inhibitor of Cdc25C, demonstrates IC50 values of 0.15 ?M for Cdc25A, 0.19 ?M for Cdc25B, and 0.06 ?M for Cdc25C. It exhibits anti-proliferative activity and enhances the expression of p-CDK1 and p-CDK2.
价 格:¥电议型 号:T73526产 地:中国大陆
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T72527Umbralisib sulfate;化合物 Umbralisib sulfateTGR-1202 sulfate ; RP-5264 sulfate|||TGR-1202 sulfate|||RP
Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL) and is applicable in the research of hematological malignancies.
价 格:¥电议型 号:T72527产 地:中国大陆
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T72526Aliskiren fumarate;化合物 Aliskiren fumarateCGP 60536 fumarate|||SPP 100 fumarate|||CGP 60536 fumarate
Aliskiren fumarate, an orally active, highly potent, and selective renin inhibitor with an IC50 of 1.5 nM, is utilized in the research of hypertension, cardiovascular diseases, and cancer cachexia.
价 格:¥电议型 号:T72526产 地:中国大陆
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T72465Umbralisib tosylate;化合物 Umbralisib tosylateRP5264 tosylate|||TGR-1202 tosylate ; RP5264 tosylate|||
Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kδ and casein kinase-1-ε (CK1ε), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 μM for PI3Kδ and CK1ε respectively, it shows unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL). This compound is utilized in the research of hematological malignancies.
价 格:¥电议型 号:T72465产 地:中国大陆
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T71526CH5164840;化合物 CH5164840CH5164840
CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity against NSCLC cell lines and xenograft models. CH5164840 has potent antitumor activity and is highly effective in combination with erlotinib against NSCLC tumors with EGFR overexpression and mutations.
价 格:¥电议型 号:T71526产 地:中国大陆
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T70526Berupipam;化合物 BerupipamBerupipam
Berupipam is a dopamine D1 receptor antagonist.
价 格:¥电议型 号:T70526产 地:中国大陆
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T69526PF-07258669;化合物 PF-07258669PF-07258669
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
价 格:¥电议型 号:T69526产 地:中国大陆
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T68526VEGFR-IN-V;化合物 VEGFR-IN-VVEGFR-IN-V
VEGFR-IN-V is a potent, vascular endothelial growth factor receptor-?2 (VEGFR-2) tyrosine kinase inhibitor.
价 格:¥电议型 号:T68526产 地:中国大陆
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T6835Fenoldopam mesylate;非诺多泮甲磺酸盐Fenoldopam methanesulfonate|||SKF-82526 mesylate|||Corlopam mesylate|||m
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
价 格:¥电议型 号:T6835产 地:中国大陆