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T5511L-765314;化合物L-765314L-765314
L-765314 is a drug which acts as a potent and selective antagonist for the Alpha-1 adrenergic receptor subtype α1B. It has mainly been used to investigate the role of α1B receptors in the regulation of blood pressure.
价 格:¥电议型 号:T5511产 地:中国大陆
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T5319Rimeporide;化合物RimeporideEMD-87580;EMD-87580
Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
价 格:¥电议型 号:T5319产 地:中国大陆
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T5318666-15;化合物666-15CREB inhibitor;CREB inhibitor
666-15 (CREB inhibitor) is a potent and selective CREB inhibitor (IC50: 81 nM).
价 格:¥电议型 号:T5318产 地:中国大陆
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T5317LCridanimod sodium;化合物 T5317LXBIO-101|||XBIO 101|||Cycloferon|||Sodium Cridanimod|||Cridanimod Na|||X
Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.
价 格:¥电议型 号:T5317L产 地:中国大陆
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T5317Cridanimod;吖啶酮乙酸CMA|||XBIO-101|||10-carboxymethyl-9-acridanone;CMA|||吖啶酮乙酸|||XBIO-101|||10-carboxyme
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
价 格:¥电议型 号:T5317产 地:中国大陆
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T5315TCA1;化合物TCA-1TCA-1|||TCA 1;TCA-1|||TCA 1
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis.
价 格:¥电议型 号:T5315产 地:中国大陆
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T5314pyridoxal isonicotinoyl hydrazone;吡哆醛异烟酰肼PIH;吡哆醛异烟酰肼|||PIH
pyridoxal isonicotinoyl hydrazone (PIH) is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.
价 格:¥电议型 号:T5314产 地:中国大陆
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T5313Sobetirome;化合物SobetiromeIACS-010759|||QRX-431;IACS-010759|||QRX-431
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
价 格:¥电议型 号:T5313产 地:中国大陆
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T5312CFTR corrector 2;化合物FDL169FDL169;FDL169
CFTR corrector 2 (FDL169) is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.
价 格:¥电议型 号:T5312产 地:中国大陆
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T5311Crocin (Gardenia Fruits Extract)西红花苷藏红花|||西红花苷
Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects.
价 格:¥电议型 号:T5311产 地:中国大陆
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T5310TR-14035;化合物TR14035MDK-1191;MDK-1191
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).
价 格:¥电议型 号:T5310产 地:中国大陆
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T4531GSK2200150A;化合物GSK2200150AGSK2200150A
GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign.
价 格:¥电议型 号:T4531产 地:中国大陆
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T4293THZ531;化合物THZ531THZ531
THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).
价 格:¥电议型 号:T4293产 地:中国大陆
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T40531THP-PEG10-OH;THP-PEG10-OHTHP-PEG10-OH;THP-PEG10-OH
THP-PEG10-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40531产 地:中国大陆
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T39531RAD16-I hydrochloride;RAD16-I hydrochlorideRAD16-I hydrochloride;RAD16-I hydrochloride
RAD16-I hydrochloride is a self-assembling peptide with nanofibrous morphology that provides an optimal microenvironment for the proliferation and differentiation of human mesenchymal stem cells (hMSC) into chondrocytes. This peptide, known as RAD16-I, has been extensively studied and serves as a model to assess the amyloid-like staining properties of self-assembling peptide nanofibers (SAPNFs).
价 格:¥电议型 号:T39531产 地:中国大陆
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T385317-TFA-ap-7-Deaza-ddG;7-TFA-ap-7-Deaza-ddG7-TFA-ap-7-Deaza-ddG
7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1), is a nucleotide derivative employed in the production of thiotriphosphate nucleotide dye terminators. These terminators are utilized in DNA sequencing reactions.
价 格:¥电议型 号:T38531产 地:中国大陆
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T37531Glycerophosphorylethanolamine (sodium salt);Glycerophosphorylethanolamine (sodium salt)Glycerophosph
Glycerophosphorylethanolamine is an active phosphodiester metabolite of phosphatidylethanolamine.1,2It promotes aggregation of amyloid-β (1-40) (Aβ40)in vitro, and levels of glycerophosphorylethanolamine are elevated in postmortem brains isolated from patients with Alzheimer’s disease.
价 格:¥电议型 号:T37531产 地:中国大陆
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T3689LRuboxistaurin mesylate;化合物 T3689LLY-333531|||LY333531|||LY 333531|||LY-333531 Mesylate;LY-333531|||L
Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
价 格:¥电议型 号:T3689L产 地:中国大陆
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T3689Ruboxistaurin hydrochloride;芦布妥林Ruboxistaurin|||LY333531 HCl|||LY 333531 hydrochloride;Ruboxistaurin
Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCβ over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 μM for PKCη, -δ, -γ, -α, -ε and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
价 格:¥电议型 号:T3689产 地:中国大陆
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T36531PAR2 (1-6) (mouse, rat);PAR2 (1-6) (mouse, rat)PAR2 (1-6) (mouse, rat);PAR2 (1-6) (mouse, rat)
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth i
价 格:¥电议型 号:T36531产 地:中国大陆