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产品数:86101
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已选条件
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TN6512TectolHL60,Ftase,Inhibitor,cell,anti-malarial,Parasite,cytotoxic,inhibit,leukemia,drug-resistant,Tec
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
价 格:¥电议型 号:TN6512产 地:中国大陆
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T7896BYK204165BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165
BYK204165 is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)
价 格:¥电议型 号:T7896产 地:中国大陆
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TP2165Urotensin II, mouse acetate (9047-55-6 free base)Urotensin II, mouse acetate (9047556 free base),Uro
Urotensin II, mouse acetate is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
价 格:¥电议型 号:TP2165产 地:中国大陆
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T26594Allisartan IsoproxilAllisartan Isoproxil
Allisartan Isoproxil is a nonpeptide antagonist of angiotensin II receptor and can be used in studies about hypertension and heart diseases.
价 格:¥电议型 号:T26594产 地:中国大陆
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T8658NEO2734PER-403,SPOP,NEO-2734,CBP,NEO 2734,MYC,HAT,NEO2734,Epigenetic Reader Domain,TC-797,Histone Ac
NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).
价 格:¥电议型 号:T8658产 地:中国大陆
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T6529Halobetasol (propionate)BMY 30056,CGP 14458,Inhibitor,Halobetasol (propionate),inhibit,CGP14458,BMY3
Halobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2
价 格:¥电议型 号:T6529产 地:中国大陆
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T10965DBPR112DBPR-112,DBPR112
DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy.
价 格:¥电议型 号:T10965产 地:中国大陆
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T7216MirogabalinDS 5565,DS-5565,Calcium Channel,Mirogabalin,inhibit,Inhibitor,Ca channels,Ca2+ channels
Mirogabalin is a calcium channel blocker with analgesic effects.
价 格:¥电议型 号:T7216产 地:中国大陆
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TQ0065PseudobufarenoginInhibitor,inhibit,Pseudobufarenogin
Pseudobufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.
价 格:¥电议型 号:TQ0065产 地:中国大陆
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T7214TEPP-46TEPP46,TEPP 46,Pyruvate Kinase,ML 265,ML-265,Inhibitor,TEPP-46,inhibit
ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. .
价 格:¥电议型 号:T7214产 地:中国大陆
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T67734MCUF-651MCUF651
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
价 格:¥电议型 号:T67734产 地:中国大陆
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T6528Gynostemma ExtractGynostemma Extract,inhibit,Endogenous Metabolite,Inhibitor
Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum.
价 格:¥电议型 号:T6528产 地:中国大陆
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T6598MPEPMetabotropic glutamate receptors,inhibit,MPEP,mGluR,Inhibitor
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
价 格:¥电议型 号:T6598产 地:中国大陆
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T12654(Rac)-Acolbifene
(Rac)-Acolbifene is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profile,relative binding affinity (RBA)=380.
价 格:¥电议型 号:T12654产 地:中国大陆
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T6594MNSthrombin,aggregation,NSC170724,Inhibitor,Src,MNS,NSC 170724,activation,inhibit,NSC-170724,Spleen
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
价 格:¥电议型 号:T6594产 地:中国大陆
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T60165VB124VB124
VB124 is an orally active, potent, and selective inhibitor of MCT4. VB124 can specifically inhibit lactate efflux with IC 50 s of 8.6 nM and 19 nM for lactate import and export in MDA-MB-231 cells, respectively. VB124 is highly selective for MCT4 over MCT1. VB124 can be used for the research of cardiac hypertrophy, heart failure, and metabolism [1].
价 格:¥电议型 号:T60165产 地:中国大陆
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T7653JNJ 303JNJ-303,JNJ 303,inhibit,Potassium Channel,JNJ303,Inhibitor,KcsA
JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
价 格:¥电议型 号:T7653产 地:中国大陆
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T6S1665IrisflorentinNOS,Irisflorentin,inhibit,Inhibitor,iNOS,Nitric oxide synthases,macrophages,inflammator
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
价 格:¥电议型 号:T6S1665产 地:中国大陆
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T10651c-Kit-IN-3cKitIN3,c Kit IN 3
c-Kit-IN-3 is a selective inhibitor of c-KIT kinase with IC50s of 4 nM and 8 nM for c-Kit (wt) and c-Kit (T670I).
价 格:¥电议型 号:T10651产 地:中国大陆