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T69059Cromoglicate sodium hydrate;化合物 Cromoglicate sodium hydrateCromoglicate sodium hydrate
Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cro
价 格:¥电议型 号:T69059产 地:中国大陆
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T69057Elliptinium acetate;化合物 CeliptiumNSC 264137|||Celiptium|||NSC 264137 ; Celiptium;NSC 264137|||Celip
Elliptinium acetate (NSC 264137), a DNA intercalating agent, exhibits high cytotoxicity towards L1210 cells and forms covalent bonds with nucleic acids from these cells. It holds potential in cancer research, especially for treating metastatic breast cancer.
价 格:¥电议型 号:T69057产 地:中国大陆
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T69056Albizziin;化合物 AlbizziinAlbizziin
Albizziin is amino acid analog which acts as a competitive inhibitor of asparagine synthetase with respect to glutamine. Albizziin has been used to isolate mutants of Chinese hamster ovary cells with alterations in levels of the target enzyme. Several classes of mutations can be distinguished on the basis of cross-resistance to beta-aspartyl hydroxamate, another amino acid analog. Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagin
价 格:¥电议型 号:T69056产 地:中国大陆
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T69055PD153035 nitrate;化合物 PD153035 nitratePD153035 nitrate
PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also
价 格:¥电议型 号:T69055产 地:中国大陆
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T69054Ciclotizolam;化合物 CiclotizolamCiclotizolam
Ciclotizolam is a drug which is a thienotriazolodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABAA receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy.
价 格:¥电议型 号:T69054产 地:中国大陆
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T69053ANAPP3;化合物 ANAPP3ANAPP3
ANAPP3 is a P2x-purinoceptor antagonist. It affects contractions in various muscle groups and tissues.
价 格:¥电议型 号:T69053产 地:中国大陆
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T69052P552-02 free base;化合物 P552-02 free baseP552-02 free base
P552-02, also known as KM-003, PS 552-02, or 552-02, is a sodium channel blocker potentially for the treatment of cystic fibrosis.
价 格:¥电议型 号:T69052产 地:中国大陆
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T69051Aculeacin A;化合物 Aculeacin AAculeacin A
Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomyces cerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A is a lipopeptide that inhibits β-glucan synthesis in yeasts. The inhibition is due to the selective blockage of glucan synthase. Aculeacin A, an amphophilic antibiotic, inhibits the biosynthesis of β?glucan by selective blockage of β(1→3) glucan synthase.
价 格:¥电议型 号:T69051产 地:中国大陆
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T69050Neostigmine hydroxide;化合物 Neostigmine hydroxideNeostigmine hydroxide
Neostigmine hydroxide is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
价 格:¥电议型 号:T69050产 地:中国大陆
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T6905Netupitant;奈妥吡坦Ro 67-31898/000|||CID 6451149;Ro 67-31898/000|||奈妥吡坦|||CID 6451149
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
价 格:¥电议型 号:T6905产 地:中国大陆
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T68905STK508411;化合物 STK508411STK508411
STK508411 is a novel inhibitor of the heterogeneous ribonuclear protein A18 (hnRNP A18).
价 格:¥电议型 号:T68905产 地:中国大陆
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T68737XR9051;化合物 XR9051XR9051
XR9051 is as a potent modulator of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) following a synthetic chemistry programme based on a natural product lead compound. XR9051 was shown to be a potent inhibitor of the binding of the cytotoxic to P-glycoprotein (EC50 = 1.4 +/- 0.5 nM). XR9051 reverses the MDR phenotype through direct interaction with P-glycoprotein.
价 格:¥电议型 号:T68737产 地:中国大陆
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T67905GS-829845;化合物GS-829845GS-829845
GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life than the parent.
价 格:¥电议型 号:T67905产 地:中国大陆
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T669053-Mercaptopropionic acid;化合物 3-Mercaptopropionic acid3-Mercaptopropionic acid
3-Mercaptopropionic Acid is a compound suitable for amino acid analysis by means of OPA.
价 格:¥电议型 号:T66905产 地:中国大陆
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T65905H-Glu(OBzl)-OBzl.TosOH;化合物 H-Glu(OBzl)-OBzl.TosOHH-Glu(OBzl)-OBzl.TosOH
H-Glu(OBzl)-OBzl.TosOH is an amino acid derivative and has a wide range of applications in life science related research.
价 格:¥电议型 号:T65905产 地:中国大陆
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T649055-Methoxy-1H-benzo[d]imidazol-2(3H)-one;化合物 5-Methoxy-1H-benzo[d]imidazol-2(3H)-one5-Methoxy-1H-benz
5-Methoxy-1H-benzo[d]imidazol-2(3H)-one is a useful organic compound for research related to life sciences. The catalog number is T64905 and the CAS number is 2080-75-3.
价 格:¥电议型 号:T64905产 地:中国大陆
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T63905Hesperadin hydrochloride;化合物 Hesperadin hydrochlorideHesperadin hydrochloride
Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.
价 格:¥电议型 号:T63905产 地:中国大陆
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T6321Tofacitinib;托法替尼Tasocitinib|||CP-690550;托法替尼|||Tasocitinib|||CP-690550
Tofacitinib (Tasocitinib) is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis.
价 格:¥电议型 号:T6321产 地:中国大陆
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T62905GLS-1-IN-1;化合物 GLS-1-IN-1GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
价 格:¥电议型 号:T62905产 地:中国大陆
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T61905RKI-1447 dihydrochloride;化合物 RKI-1447 dihydrochlorideRKI-1447 dihydrochloride
RKI 1447 dihydrochloride is an effective and selective ROCK inhibitor (ROCK1 IC50=14.5 nM, ROCK2 IC50=6.2 nM). RKI 1447 dihydrochloride can inhibit the growth of colorectal cancer cells and promote cell apoptosis.
价 格:¥电议型 号:T61905产 地:中国大陆