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T62991Mpro/PLpro-IN-1;化合物 Mpro/PLpro-IN-1Mpro/PLpro-IN-1
Mpro/PLpro-IN-1 (Compound 29) is a dual-acting inhibitor of SARS-CoV-2 protease.Mpro/PLpro-IN-1 is also a potent inhibitor of Mpro/PLpro, with micromolar inhibition of M pro (IC50:1.72 μM) and submicromolar inhibition of PL pro (IC50:0.67 μM). (IC50:0.67 μM).
价 格:¥电议型 号:T62991产 地:中国大陆
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T61991HTT-D3;化合物 HTT-D3HTT-D3
HTT-D3 is a potent and orally active huntingtin (HTT) splicing modulator. HTT-D3 can lead to HTT mRNA degradation and reduction of HTT levels. HTT-D3 reduces p-glycoprotein (P-gp) efflux, and has research value in Huntington´s disease.
价 格:¥电议型 号:T61991产 地:中国大陆
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T60991Factor VII-IN-1;化合物 Factor VII-IN-1Factor VII-IN-1
Factor VII-IN-1 (example 43) has anticoagulant activities that is a potent factor VII (FVII) inhibitor with an IC50 value of 1.1 μM [1].
价 格:¥电议型 号:T60991产 地:中国大陆
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T5030Zofenopril calcium;佐芬普利钙SQ26991|||Zofenopril (calcium);SQ26991|||佐芬普利钙|||Zofenopril (calcium)
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound zofenoprilat, which is an angiotensin converting enzyme (ACE) inhibitor . Zofenopril promotes the regeneration of peripheral nerve injuries in rat models . Zofenopril increases SR calcium cycling and stimulates active calcium uptake into the SR .
价 格:¥电议型 号:T5030产 地:中国大陆
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T4991LErtapenem (sodium salt);化合物 T4991LErtapenem (sodium salt)
Ertapenem (sodium salt) is a useful organic compound for research related to life sciences. The catalog number is T4991L and the CAS number is 153832-38-3.
价 格:¥电议型 号:T4991L产 地:中国大陆
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T4991Ertapenem sodium;厄他培南钠MK-826|||L-749345;厄他培南钠|||MK-826|||L-749345|||尔他培南钠
Ertapenem sodium (MK-826) is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases.
价 格:¥电议型 号:T4991产 地:中国大陆
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T4099119-Heptatriacontanol;19-Heptatriacontanol19-Heptatriacontanol|||19-Hydroxyheptatriacontane;19-Heptat
19-Heptatriacontanol is used to combine macromolecules and small molecules.
价 格:¥电议型 号:T40991产 地:中国大陆
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T3999118-Oxocortisol;18-Oxocortisol18-Oxocortisol
18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.
价 格:¥电议型 号:T39991产 地:中国大陆
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T39919A 410099.1, amine-Boc hydrochloride;A 410099.1, amine-Boc hydrochlorideA 410099.1, amine-Boc hydroch
A 410099.1, amine-Boc hydrochloride, serves as a functionalized IAP (Inhibitor of Apoptosis Proteins) ligand instrumental in the synthesis of PROTACs (Proteolysis Targeting Chimeras), notably those targeting BTK (Bruton´s Tyrosine Kinase), including PROTACs 4 and 5.
价 格:¥电议型 号:T39919产 地:中国大陆
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T39918(±)-Phrymarolin II;(±)-Phrymarolin II(±)-Phrymarolin II
(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.
价 格:¥电议型 号:T39918产 地:中国大陆
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T39917Thalidomide-O-C2-acid;Thalidomide-O-C2-acidThalidomide-O-C2-acid;Thalidomide-O-C2-acid
Thalidomide-O-C2-acid is a compound designed by synthesizing an E3 ligase ligand-linker conjugate. It comprises a cereblon ligand derived from Thalidomide and a linker commonly used in PROTAC technology.
价 格:¥电议型 号:T39917产 地:中国大陆
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T39916GNE-274;GNE-274GNE-274
GNE-274, a non-degrader compound structurally similar to GDC-0927 (an ER degrader), serves as a partial ER agonist in breast cancer cell lines without triggering ER turnover. Notably, GNE-274 enhances chromatin accessibility at ER-DNA binding sites, unlike GDC-0927. Acting as a potent inhibitor of the ER-ligand binding domain (LBD), GNE-274 exhibits potential for cancer research purposes.
价 格:¥电议型 号:T39916产 地:中国大陆
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T39915Trx-red;Trx-redTrx-red|||NBL-SS perchlorate;Trx-red|||NBL-SS perchlorate
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derived from the nile blue fluorophore. It is specifically designed for imaging thioredoxin (Trx) in live cells and in vivo, with excitation and emission wavelengths of 615 nm and 661 nm, respectively.
价 格:¥电议型 号:T39915产 地:中国大陆
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T39914ARB-272572;ARB-272572ARB-272572
ARB-272572 is a potent small-molecule PD-L1 inhibitor with an IC 50 value of 400 pM.
价 格:¥电议型 号:T39914产 地:中国大陆
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T39913TMX-4100;TMX-4100TMX-4100
TMX-4100 is a potent degrader of phosphodiesterase 6D (PDE6D), exhibiting high degradation selectivity towards PDE6D with DC50 values below 200 nM in MOLT4, Jurkat, and MM.1S cells. This compound holds significant potential for research pertaining to multiple myeloma.
价 格:¥电议型 号:T39913产 地:中国大陆
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T39911Cl-PEG6-acid;Cl-PEG6-acidCl-PEG6-acid;Cl-PEG6-acid
Cl-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T39911产 地:中国大陆
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T39910Desmorpholinyl Navitoclax-NH-Me;化合物Desmorpholinyl Navitoclax-NH-MeDesmorpholinyl ABT-263-NH-Me|||Des
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].
价 格:¥电议型 号:T39910产 地:中国大陆
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T389919-Oxoheptadecanedioic acid;9-Oxoheptadecanedioic acid9-Oxoheptadecanedioic acid
9-Oxoheptadecanedioic acid (compound 46), serving as a precursor to Civetone, is utilized in protein labeling.
价 格:¥电议型 号:T38991产 地:中国大陆
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T3799115-keto Prostaglandin F2α;化合物15-keto Prostaglandin F2α15-keto Prostaglandin F2α|||15-keto PGF2α;15-k
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
价 格:¥电议型 号:T37991产 地:中国大陆
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T36991Monascuspiloin;MonascuspiloinMonascuspiloin
Monascuspiloin is a fungal metabolite that has been found inM. pilosusM93-fermented rice.1It induces endoplasmic reticulum stress and autophagy in PC3 prostate cancer cells. Monascuspiloin (15-45 μM) decreases viability of PC3 cells and has an additive effect on the reduction in viability of PC3 cells induced by irradiation when used at a concentration of 25 μM. It induces intratumor apoptosis and autophagy and reduces tumor growth in a PC3 mouse xenograft model when administered at doses of 40
价 格:¥电议型 号:T36991产 地:中国大陆