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T62853UNC9994 hydrochloride;化合物 UNC9994 hydrochlorideUNC9994 hydrochloride
UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist (Ki: 79 nM) that selectively activates β- arresttin recruitment and signal transduction. UNC9994 hydrochloride is a Gi-regulated antagonist of cAMP production and a partial agonist of the D2R/β-arrestin-2 interaction, exhibiting psychostimulatory effects.
价 格:¥电议型 号:T62853产 地:中国大陆
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T61994AChE/BChE-IN-8;化合物 AChE/BChE-IN-8AChE/BChE-IN-8
AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor. AChE/BChE-IN-8 shows Ki of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 has blood-brain barrier permeability and low cytotoxicity.
价 格:¥电议型 号:T61994产 地:中国大陆
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T60994FTO-IN-6;化合物 FTO-IN-6FTO-IN-6
FTO-IN-6 is a selective inhibitor of fat mass and obesity associated protein (FTO).
价 格:¥电议型 号:T60994产 地:中国大陆
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T5S0994N-Methylcytisine;N-甲基野靛碱Caulophylline;N-甲基野靛碱|||Caulophylline
1. N-Methylcytisine (Caulophylline)´s nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N, N-dimethylcytisine did not displace 14C-tubocurarine at a concentration of .1 mM, cytisine was the only effective inhibitor of 14C-tubocurarine specific binding (Ki=7 nM).
价 格:¥电议型 号:T5S0994产 地:中国大陆
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T5994KPT-6566;化合物KPT-6566inhibit|||2-[[4-[[[4-(叔丁基)苯基]磺酰基]亚氨基]-1-氧代-1,4-二氢-2-萘基]硫基]乙酸|||Cyclin D1|||ROS||
KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity.
价 格:¥电议型 号:T5994产 地:中国大陆
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T4994Tocofersolan;托可索仑Vitamin E-TPGS|||Tocophersolan|||TPGS|||D-α-Tocopherol polyethylene glycol 1000 suc
Tocofersolan (TPGS) is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.
价 格:¥电议型 号:T4994产 地:中国大陆
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T40994T-2307;T-2307T-2307
T-2307, a broad-spectrum arylamidine compound, demonstrates potent antifungal properties both in vitro and in vivo. Its activity extends to clinically significant pathogens such as Candida species (MIC range: 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range: 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range: 0.0156 to 4 μg/mL).
价 格:¥电议型 号:T40994产 地:中国大陆
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T39994Sovilnesib;化合物SovilnesibAMG650;AMG650
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
价 格:¥电议型 号:T39994产 地:中国大陆
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T39949(S,R,S)-AHPC-Me-decanedioic acid;(S,R,S)-AHPC-Me-decanedioic acid(S,R,S)-AHPC-Me-decanedioic acid
(S,R,S)-AHPC-Me-decanedioic acid is a ligand-linker conjugate for E3 ligases, designed for the synthesis of PROTACs.
价 格:¥电议型 号:T39949产 地:中国大陆
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T39947WSF1-IN-1WSF1-IN-1WSF1-IN-1
WSF1-IN-1 (compound 136) is an orally active inhibitor of WSF1, intended for the study of WSF1-related tumors in patients with Wolfram syndrome (WS). In HepG2 parental and HepG2 WFS1 KO cell lines, WSF1-IN-1 has demonstrated IC50 values of 0.33 μM and >27 μM, respectively.
价 格:¥电议型 号:T39947产 地:中国大陆
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T39946IDO1-IN-12IDO1-IN-12IDO1-IN-12
IDO1-IN-12 is a potent and orally available IDO1 inhibitor.
价 格:¥电议型 号:T39946产 地:中国大陆
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T39945SYY-B085-1SYY-B085-1SYY-B085-1
SYY-B085-1 is a histone acetyltransferase (HAT) inhibitor.
价 格:¥电议型 号:T39945产 地:中国大陆
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T39944HSD1590;HSD1590HSD1590
HSD1590 is a highly effective and potent inhibitor of ROCK1 and ROCK2, with IC50 values of 1.22 nM and 0.51 nM, respectively. It demonstrates exceptional binding affinity to ROCK, with Kd values below 2 nM. Moreover, HSD1590 showcases minimal cytotoxicity, making it an ideal compound for various applications.
价 格:¥电议型 号:T39944产 地:中国大陆
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T39943CDK7-IN-6CDK7-IN-6CDK7-IN-6
CDK7-IN-6 is a highly effective and specific inhibitor (IC50 ≤100 nM) of cyclin-dependent kinase 7 (CDK7). It showcases remarkable selectivity, with more than a 200-fold preference for CDK7 over CDK1, CDK2, and CDK5. This compound holds significant potential for cancer research purposes.
价 格:¥电议型 号:T39943产 地:中国大陆
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T39942MP-PEG4-VK(Boc)G-OSu;MP-PEG4-VK(Boc)G-OSuMP-PEG4-VK(Boc)G-OSu;MP-PEG4-VK(Boc)G-OSu
MP-PEG4-VK(Boc)G-OSu is a cleavable ADC linker employed for the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T39942产 地:中国大陆
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T39941MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT;MP-PEG4-Val-Lys-Gly-7-MAD-MDCPTMP-PEG4-Val-Lys-Gly-7-MAD-MDCPT;MP-PE
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a drug-linker conjugate for antibody-drug conjugate (ADC).
价 格:¥电议型 号:T39941产 地:中国大陆
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T39940Plazinemdor;PlazinemdorPlazinemdor
Plazinemdor is an NMDA receptor positive allosteric modulator with potential applications in psychiatric, neurological, neurodevelopmental disorders, and diseases of the nervous system.
价 格:¥电议型 号:T39940产 地:中国大陆
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T3994Verinurad;维立诺雷RDEA3170;RDEA3170|||维立诺雷
Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
价 格:¥电议型 号:T3994产 地:中国大陆
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T38994NHS-5(6)Carboxyrhodamine;NHS-5(6)CarboxyrhodamineNHS-5(6)Carboxyrhodamine
NHS-5(6)Carboxyrhodamine is a fluorescent dye employed for precise labeling of proteins through fluorescence. This compound enables the achievement of accurate ratios of dye to protein, even when used under native conditions.
价 格:¥电议型 号:T38994产 地:中国大陆
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T3799416-hydroxy Hexadecanoic Acid16-羟基十六烷酸Juniperic acid
16-hydroxy Hexadecanoic Acid (Juniperic acid) is a compound isolated from the leaves and stems of Arabidopsis thaliana and can be used to prevent, alleviate, or treat metabolic diseases.
价 格:¥电议型 号:T37994产 地:中国大陆