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  • T0124UK-124114西拉菌素;UNII-A2669OWX9N;Selamectin

    UK-124114 is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth i

    价 格:¥电议型 号:T0124产 地:中国大陆

  • T10125(3R,4R)-A2-32-01(3R,4R)-A2-32-01

    (3R,4R)-A2-32-01 (compound 2) is a specific caseinolytic protein proteases (ClpP) inhibitor (EC50: 4.5 μM).

    价 格:¥电议型 号:T10125产 地:美洲

  • T101374-?Bromo A231874-?Bromo A23187

    4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.

    价 格:¥电议型 号:T10137产 地:美洲

  • T10659Ca2+ channel agonist 1Ca2+ channel agonist 1

    Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.

    价 格:¥电议型 号:T10659产 地:美洲

  • T11874Lp-PLA2-IN-3Lp-PLA2-IN-3

    Lp-PLA2-IN-3 is a potent and orally bioavailable lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp-PLA2 .?

    价 格:¥电议型 号:T11874产 地:美洲

  • T11875LPA2 antagonist 2LPA2 antagonist 2

    LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM.

    价 格:¥电议型 号:T11875产 地:美洲

  • T15146DNA2 inhibitor C5DNA2 inhibitor C5

    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclea

    价 格:¥电议型 号:T15146产 地:美洲

  • T15782Lp-PLA2 -IN-1Lp-PLA2 -IN-1

    Lp-PLA2 -IN-1 suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2 -IN-1also inhibits to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example, atherosclerosis, Alzh

    价 格:¥电议型 号:T15782产 地:美洲

  • T15786LPA2 antagonist 1LPA2 antagonist 1

    LPA2 antagonist 1 is an LPA2 antagonist (IC50: 17 nM).

    价 格:¥电议型 号:T15786产 地:美洲

  • T2254A-205804A-205804,A205804,A 205804

    A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.

    价 格:¥电议型 号:T2254产 地:美洲

  • T2395LVortioxetine HBrVortioxetine HBr,Lu AA21004 hydrobromide,Vortioxetine hydrobromide

    Vortioxetine (Lu AA21004) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).

    价 格:¥电议型 号:T2395L产 地:美洲

  • T2423P7C3-A20P7C3-A20

    P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer´s disease and similar neurodegenerative disorders.

    价 格:¥电议型 号:T2423产 地:美洲

  • T4A2456GamabufotalinGamabufotalin,Gamabufagin,

    1. Gamabufotalin , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.

    价 格:¥电议型 号:T4A2456产 地:美洲

  • T4A2458ResibufogeninResibufogenin,Recibufogenin,Bufogenin

    1. Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogeni

    价 格:¥电议型 号:T4A2458产 地:美洲

  • T4A2462TelocinobufaginTelocinobufagin,Telocinobufogenin,Telobufotoxin

    1. Telocinobufagin is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice challenged with live S. typhimurium. 3. Telocinobufagin

    价 格:¥电议型 号:T4A2462产 地:美洲

  • T5067Flavin Adenine Dinucleotide DisodiumFlavin Adenine Dinucleotide Disodium,FAD sodium salt,FAD-Na2

    FAD is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5´-monophosphate. FAD functions as a coenzyme that facilitates the transfer of electrons by flavoenzymes in oxidation-reduction reactions in cells

    价 格:¥电议型 号:T5067产 地:美洲

  • T5A2455ArenobufaginArenobufagin

    Arenobufagin is a natural bufadienolide from toad venom with potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/ADM cells.

    价 格:¥电议型 号:T5A2455产 地:美洲

  • T5A2461BufotalineBufotaline,Bufotalin,

    1. Bufotaline is a kind of poisonous secretions of toads.

    价 格:¥电议型 号:T5A2461产 地:美洲

  • T83722FALGPA TFA;化合物 FALGPA TFA2-Furanacryloyl-L-leucylglycyl-L-prolyl-L-alanine|||2-Furanacryloyl-Leu-Gly

    FALGPA, a colorimetric substrate for collagenase, exhibits selectivity over trypsin, thermolysin, and elastase. It uniquely interacts with collagenase, which binds to and cleaves the Leu-Gly (LG) peptide sequence, releasing the furanacryloyl group. This release is measurable through colorimetric detection between 324 and 345 nm, serving as an indicator of collagenase activity. Additionally, FALGPA facilitates the identification of inhibitors for C. histolyticum collagenase.

    价 格:¥电议型 号:T83722产 地:中国大陆

  • T83704A20FMDV2 TFA;化合物 A20FMDV2 TFAA20FMDV2 TFA

    A20FMDV2, a peptide derived from the α-helical RGD cell-interacting domain of the VP1 capsid protein of foot-and-mouth disease virus (FMDV) serotype O, targets and binds αVβ6 integrin. It effectively disrupts αVβ6 integrin-mediated cell adhesion in H357 tongue squamous cell carcinoma cells that exhibit human αVβ6, with an inhibitory concentration (IC50) of 1.2 ?M. Additionally, when labeled with 111indium-DTPA, A20FMDV2 (20 MBq) specifically attaches to αVβ6 integrin in a breast cancer mouse xen

    价 格:¥电议型 号:T83704产 地:中国大陆

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