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TN6714Geranylgeraniolmitochondria,neuronal death,neuroinflammation,apoptosis,cholesterol pathway,NF-κB,inh
Geranylgeraniol is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.
价 格:¥电议型 号:TN6714产 地:中国大陆
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T64348WAY-313137
WAY-313137 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells).
价 格:¥电议型 号:T64348产 地:中国大陆
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T9805BAY 2666605anticancer effect,inhibit,BAY 2666605,orally active,PDE3A-SLFN12 Complex,Phosphodiesteras
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.
价 格:¥电议型 号:T9805产 地:中国大陆
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T7359CAY10471 RacemateCAY 10471,CAY10471,TM30089,Inhibitor,CAY-10471,TM 30089,TM-30089,CAY10471 Racemate,
CAY 10471 is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2, DP1, and TP receptors( Ki values of 0.6, 1200, and >10,000 nM,respectively)
价 格:¥电议型 号:T7359产 地:中国大陆
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T37826CAY10462
CAY10462 is an effective and selective inhibitor of the 20-HETE synthase CYP4A11 with an IC50 of 8.8 nM. CAY10462 exhibits nearly 200 times less potent for 1A, 1C, and 3A CYP450 enzymes.
价 格:¥电议型 号:T37826产 地:中国大陆
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T13345Wnt pathway activator 2Wnt pathway activator 2
Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.
价 格:¥电议型 号:T13345产 地:中国大陆
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T6322CopanlisibBAY 80-6946;可泮利塞;库潘尼西
Copanlisib is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell
价 格:¥电议型 号:T6322产 地:中国大陆
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T6206PHA-767491PHA767491;PHA 767491;CAY10572
PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.
价 格:¥电议型 号:T6206产 地:中国大陆
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T6204QNZCAY10470;EVP4593
QNZ (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.
价 格:¥电议型 号:T6204产 地:中国大陆
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T6166TelatinibBay 57-9352;替拉替尼
Telatinib is an effective inhibitor of VEGFR2/3, c-Kit, and PDGFRα. The IC50s of Telatinib forVEGFR2/3, c-Kit and PDGFRα are 6 nM/4 nM, 1 nM, and 15 nM, respectively.
价 格:¥电议型 号:T6166产 地:中国大陆
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T6053Turofexorate Isopropyl妥芬异丙酯;FXR-450;XL335;WAY-362450
Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
价 格:¥电议型 号:T6053产 地:中国大陆
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T60006WAY-620057
WAY-620057 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases.
价 格:¥电议型 号:T60006产 地:中国大陆
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T60005WAY-296817
WAY-296817 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases.
价 格:¥电议型 号:T60005产 地:中国大陆
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T5S1889Yunaconitine滇乌头碱;Guayewuanine B
1. Yunaconitine has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows positive effect in the granuloma inhibition test when
价 格:¥电议型 号:T5S1889产 地:中国大陆
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T5622BAY-218AHR antagonist 1
AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
价 格:¥电议型 号:T5622产 地:中国大陆
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T5418BAY-293
BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).
价 格:¥电议型 号:T5418产 地:中国大陆
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T5358Longdaysin
Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).
价 格:¥电议型 号:T5358产 地:中国大陆
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T5325Nifurtimox硝呋替莫;BAY-2502;BAY-A-2502
Nifurtimox is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi- epimastigotes, respectively).
价 格:¥电议型 号:T5325产 地:中国大陆
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T5208BAY-8002BAY8002;BAY 8002
BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).
价 格:¥电议型 号:T5208产 地:中国大陆
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T5195AlrestatinAY-22284;阿瑞司他丁
Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
价 格:¥电议型 号:T5195产 地:中国大陆