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T14378AZD5582AZD5582
AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs). Which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis[1].
价 格：￥电议型 号：T14378产 地：美洲
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T14379AZD5904AZD5904
AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM. Which has similar potency in mouse and rat.
价 格：￥电议型 号：T14379产 地：美洲
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T14380AZD7507AZD7507
AZD7507 is a CSF-1R inhibitor. It has antitumor activity.
价 格：￥电议型 号：T14380产 地：美洲
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T14382AZD7687AZD7687
AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent
价 格：￥电议型 号：T14382产 地：美洲
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T14383AZD8329AZD8329
AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1. Which displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].
价 格：￥电议型 号：T14383产 地：美洲
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T14384AZD8797AZD8797
AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor. For antagonizes CX3CR1 and CXCR2, the Kis values are 3.9 and 2800 nM, respectively.
价 格：￥电议型 号：T14384产 地：美洲
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T14385AZD9056 hydrochlorideAZD9056 hydrochloride
AZD9056 hydrochloride is a P2X7 inhibitor. Which plays a significant role in pain-causing diseases and inflammation.
价 格：￥电议型 号：T14385产 地：美洲
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T14386AZD9567AZD9567
AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. It shows excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].
价 格：￥电议型 号：T14386产 地：美洲
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T15706LanicemineLanicemine,AZD6765,
Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1?μM).
价 格：￥电议型 号：T15706产 地：美洲
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T16114PavinetantPavinetant,MLE-4901,AZD2624
Pavinetant is an antagonist of the neurokinin-3 receptor (NK3R).
价 格：￥电议型 号：T16114产 地：美洲
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T1741AZD1080AZD1080
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.
价 格：￥电议型 号：T1741产 地：美洲
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T1836AZD2932AZD2932
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
价 格：￥电议型 号：T1836产 地：美洲
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T1859AZD8055AZD8055
AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.
价 格：￥电议型 号：T1859产 地：美洲
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T1920CapivasertibCapivasertib,AZD5363,
Capivasertib (AZD5363) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: 3/7/7 nM for Akt1/2/3).
价 格：￥电议型 号：T1920产 地：美洲
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T1948AZD4547AZD4547
AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).
价 格：￥电议型 号：T1948产 地：美洲
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T1957AZD2858AZD2858
AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.
价 格：￥电议型 号：T1957产 地：美洲
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T1961VistusertibVistusertib,AZD2014,
AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.
价 格：￥电议型 号：T1961产 地：美洲
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T2077AdavosertibAdavosertib,MK-1775,AZD1775
MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.
价 格：￥电议型 号：T2077产 地：美洲
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T2300AZD1208AZD1208
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.
价 格：￥电议型 号：T2300产 地：美洲
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