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T6384Ammonium Glycyrrhizinate;甘草酸单铵盐Glycyram|||Glycamil|||AMGZ;Glycyram|||甘草酸单铵盐|||Glycamil|||AMGZ
Ammonium Glycyrrhizinate (Glycyram) inhibits the cytopathology and growth of several unrelated DNA/RNA viruses.
价 格:¥电议型 号:T6384产 地:中国大陆
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T61851PTP1B-IN-3 diammonium;化合物 PTP1B-IN-3 diammoniumPTP1B-IN-3 diammonium
PTP1B-IN-3 diammonium is a highly effective and orally bioavailable inhibitor of the protein tyrosine phosphatase 1B (PTP1B) enzyme, with an IC50 value of 120 nM for both PTP1B and TCPTP. This compound exhibits potent antidiabetic and anticancer properties, as supported by extensive research [1] [2].
价 格:¥电议型 号:T61851产 地:中国大陆
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T5300Ammonium formate甲酸铵甲酸铵|||Formic acid ammonium salt
Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that es
价 格:¥电议型 号:T5300产 地:中国大陆
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T5258Dodecanedioic acid diammonium salt;十二烷二酸 二铵盐1,10-Decanedicarboxylic acid diammonium salt;十二烷二酸 二铵盐||
Dodecanedioic acid diammonium salt (1,10-Decanedicarboxylic acid diammonium salt) is a dicarboxylic acid which is water-soluble and involves in a metabolic pathway intermediate to those of lipids and carbohydrates.
价 格:¥电议型 号:T5258产 地:中国大陆
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T4827Trimethylammonium chloride;三甲胺盐酸盐Trimethylamine hydrochloride;三甲胺盐酸盐|||Trimethylamine hydrochloride
Trimethylammonium chloride (Trimethylamine hydrochloride) is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagina infections, and bad breath. It is also associated with taking large doses of choline. Trimethylaminuria is a genetic disorder in which the body is unable to metabolize trimethylamine from food sources. Patients develop a characteristic fish odour of their sweat, urine, and brea
价 格:¥电议型 号:T4827产 地:中国大陆
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T4702(3-Carboxypropyl)trimethylammonium chloride;(3-羧丙基)三甲基氯化铵γ-Butyrobetaine hydrochloride|||(3-Carboxyp
(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) is a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).
价 格:¥电议型 号:T4702产 地:中国大陆
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T40239Tenofovir-C3-O-C15-CF3 ammonium;Tenofovir-C3-O-C15-CF3 ammoniumTenofovir-C3-O-C15-CF3 ammonium;Tenof
Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsomes. It exhibits potent anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo.
价 格:¥电议型 号:T40239产 地:中国大陆
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T40238Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium;Tenofovir-C3-O-C12-trimethylsilylacetylene ammon
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) displays a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes. Moreover, it demonstrates potent in vitro anti-HIV activity and improves in vivo pharmacokinetic properties.
价 格:¥电议型 号:T40238产 地:中国大陆
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T39510DL-TBOA ammonium;DL-TBOA ammoniumDL-TBOA ammonium
DL-TBOA ammonium is a potent, non-transportable inhibitor of excitatory amino acid transporters. Its inhibitory effects are demonstrated by IC50 values of 70 μM, 6 μM, and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2, and EAAT3, respectively. Additionally, DL-TBOA ammonium significantly hampers the uptake of [14C]glutamate in COS-1 cell lines expressing human EAAT1 and EAAT2, evident by Ki values of 42 μM and 5.7 μM, respectively. Furthermore, this compound competitively blocks EA
价 格:¥电议型 号:T39510产 地:中国大陆
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T39183Okadaic acid ammonium salt;冈田酸铵盐Okadaic acid ammonium salt
Okadaic acid ammonium salt, a marine toxin, serves as an inhibitor of protein phosphatases (PP), displaying a higher affinity for PP2A (IC 50 =0.1-0.3 nM) alongside inhibitory effects on PP1 (IC 50 =15-50 nM), PP3 (IC 50 =3.7-4 nM), PP4 (IC 50 =0.1 nM), and PP5 (IC 50 =3.5 nM), but does not affect PP2C. By inhibiting PPs, this compound promotes protein phosphorylation and acts as a tumor promoter. Additionally, it is involved in inducing tau phosphorylation.
价 格:¥电议型 号:T39183产 地:中国大陆
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T38635Kdo2-Lipid A ammonium;Kdo2-Lipid A铵盐Kdo2-Lipid A ammonium
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.
价 格:¥电议型 号:T38635产 地:中国大陆
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T38570DMAPP triammonium;DMAPP三铵盐Dimethylallyl diphosphate triammonium|||Dimethylallyl Pyrophosphate triamm
DMAPP triammonium (Dimethylallyl diphosphate triammonium) is one of the prerequisite substances for an isoprenoid involved in the mevalonate (MVA) pathway, which can be used in the study of metabolism-related diseases.
价 格:¥电议型 号:T38570产 地:中国大陆
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T37964Dicresulene diammonium;Dicresulene diammoniumDicresulene diammonium
Dicresulene diammonium is an impurity found in Policresulen, which is an organic acid possessing hemostatic, antimicrobial, and antiviral properties[1][2].
价 格:¥电议型 号:T37964产 地:中国大陆
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T37775Farnesyl Pyrophosphate (ammonium salt);Farnesyl Pyrophosphate (ammonium salt)Farnesyl Pyrophosphate
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 μM), attenuating platelet aggregation. It has also been shown to regulate adipocyte function as an endogenous PPARγ agonist. Additionally, because of a flexible hydrocarbon chain that enables different conformat
价 格:¥电议型 号:T37775产 地:中国大陆
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T37691Phosphatidic Acids (egg) (ammonium salt);Phosphatidic Acids (egg) (ammonium salt)Phosphatidic Acids
Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular
价 格:¥电议型 号:T37691产 地:中国大陆
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T37687Cyclic ADP-ribose ammonium;Cyclic ADP-ribose ammoniumCyclic ADP-ribose ammonium
Cyclic ADP-ribose ammonium (cADPR ammonium) is a powerful calcium mobilization second messenger synthesized from NAD+ by an ADP-ribosyl cyclase. It primarily raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum, while also facilitating extracellular influx through the opening of TRPM2 channels [1][2][3].
价 格:¥电议型 号:T37687产 地:中国大陆
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T37582Ganglioside GM1 Mixture (ovine) (ammonium salt);Ganglioside GM1 Mixture (ovine) (ammonium salt)Gangl
Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i
价 格:¥电议型 号:T37582产 地:中国大陆
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T37475Cyclic ADP-Ribose (ammonium salt);Cyclic ADP-Ribose (ammonium salt)cADP-Ribose|||cADPR|||Cyclic ADP-
Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second messenger is generated via the cADP-ribose synthases CD38 and CD157.[6],[5],[7] cADP-Ribose may also trigger the cell surface Ca2+ influx channel TRPM2 in a temperature-dependent manner.[8]
价 格:¥电议型 号:T37475产 地:中国大陆
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T373465-Hydroxytoluene-2,4-disulphonic acid diammonium;5-Hydroxytoluene-2,4-disulphonic acid diammonium5-H
5-Hydroxytoluene-2,4-disulphonic acid diammonium, an impurity of Policresulen, is a significant NS2B/NS3 protease inhibitor, exhibiting an IC50 value of 0.48 μg/mL. It inhibits DENV2 virus replication in BHK-21 cells effectively, with an IC50 of 4.99 μg/mL. Policresulen functions as a competitive inhibitor, marginally impacting the protease´s stability[1].
价 格:¥电议型 号:T37346产 地:中国大陆
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T37315Fluo-3 (ammonium salt);Fluo-3 (ammonium salt)Fluo-3 (ammonium salt)
Fluo-3 (ammonium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. [1] Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
价 格:¥电议型 号:T37315产 地:中国大陆