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T10466BAY-1797BAY-1797
BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels.
价 格:¥电议型 号:T10466产 地:美洲
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T10467BAY-1816032BAY-1816032
BAY-1816032 is a potent and orally available inhibitor of bidding uninhibited by benzimidazoles 1 ( BUB1) kinase (IC50: 7 nM).
价 格:¥电议型 号:T10467产 地:美洲
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T10470BAY-545BAY-545
BAY-545 is a potent and selective A2B adenosine receptor antagonist (IC50: 59 nM). BAY-545 also exhibits IC50s of 66, 280, 400 nM for human, rat, mouse A2B adenosine receptor in cells, respectively.
价 格:¥电议型 号:T10470产 地:美洲
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T10472Bay 65-1942 R formBay 65-1942 R form
Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.
价 格:¥电议型 号:T10472产 地:美洲
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T10473BAY-678BAY-678
BAY-678 is an orally bioavailable, selective and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).
价 格:¥电议型 号:T10473产 地:美洲
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T10473LBAY-677BAY-677
BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM[1] and it is also nominated as a chemical probe to the public vi
价 格:¥电议型 号:T10473L产 地:美洲
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T10477BAY-985BAY-985
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.
价 格:¥电议型 号:T10477产 地:美洲
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T10480Bay 41-4109 (less active enantiomer)Bay 41-4109 (less active enantiomer)
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).
价 格:¥电议型 号:T10480产 地:美洲
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T10480LBay 41-4109Bay 41-4109
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).
价 格:¥电议型 号:T10480L产 地:美洲
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T10481BAY 73-6691 racemateBAY 73-6691 racemate
BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor sourced from patent WO 2017070293 A1.
价 格:¥电议型 号:T10481产 地:美洲
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T10481LBAY 73-6691BAY 73-6691,(R)-BAY 73-6691,
BAY 73-6691 is an inhibitor of brain penetrant PDE9A.
价 格:¥电议型 号:T10481L产 地:美洲
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T10518BET-BAY 002BET-BAY 002
BET-BAY 002 is an effective BET inhibitor and exhibits efficacy in a multiple myeloma model.
价 格:¥电议型 号:T10518产 地:美洲
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T1146NifedipineNifedipine,BAY-a-1040,Procardia
Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and
价 格:¥电议型 号:T1146产 地:美洲
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T1184RivaroxabanRivaroxaban,BAY 59-7939,
Rivaroxaban is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothro
价 格:¥电议型 号:T1184产 地:美洲
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T1187BifonazoleBifonazole,Bay H-4502,
Bifonazole acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essential component of fungal cell membranes. This is
价 格:¥电议型 号:T1187产 地:美洲
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T12613LBAY-85-8501BAY-85-8501
BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE). With an IC50 of 65 pM.
价 格:¥电议型 号:T12613L产 地:美洲
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T12660(Rac)-BAY1238097(Rac)-BAY1238097
(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.
价 格:¥电议型 号:T12660产 地:美洲
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T12660LBAY1238097BAY1238097
BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different MM (multiple myeloma) and AML (acute myeloid leukemia) models through down-regulation of c-Myc levels and its downstream tran
价 格:¥电议型 号:T12660L产 地:美洲
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T13295VeliflaponVeliflapon,BAY X 1005,DG-031
Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP) . Veliflapon inhibits the synthesis of the leukotrienes B4 and C4.
价 格:¥电议型 号:T13295产 地:美洲