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T83868(±)13,14-EDT;化合物 (±)13,14-EDT(±)13,14-Epoxydocosatrienoic Acid|||(±)13,14-EpDoTrE|||(±)-Dihomo-13,14
(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619.
价 格:¥电议型 号:T83868产 地:中国大陆
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T83857Soluble Epoxide Hydrolase PROTAC 1a;化合物 Soluble Epoxide Hydrolase PROTAC 1asEH Proteolysis-targeting
Soluble epoxide hydrolase (sEH) PROTAC 1a is a proteolysis-targeting chimera (PROTAC) comprising a cereblon ligand linked to the sEH inhibitor t-TUCB via a linker, promoting selective sEH degradation and inhibiting its hydrolase activity (IC50 = 0.8 nM) significantly more than its phosphatase activity (IC50 = >10,000 nM). This compound preferentially targets cytosolic sEH for lysosomal rather than proteasomal degradation. Furthermore, it mitigates thapsigargin-induced upregulation of phosphoryla
价 格:¥电议型 号:T83857产 地:中国大陆
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T83578(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol;化合物 (19R,23E)-5b,19-Epoxy19-ethoxycucu
(19R,23E)-5b,19-Epoxy-19-ethoxycucurbita-6,23-diene-3b,25-diol, a cucurbitane-type triterpenoid, exhibited no activity against five cancer cell lines—MCF-7, HepG2, Du145, Colon205, and HL-60—when evaluated using the MTT assay [1].
价 格:¥电议型 号:T83578产 地:中国大陆
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T83570(23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol;化合物 (23E)-5b,19-epoxycucurbita-6,23,25(26)-trien
(23E)-5β,19-epoxycucurbita-6,23,25(26)-triene-3β-ol, a cucurbitane triterpenoid, can be isolated from the seeds of Momordica charantia L. [1].
价 格:¥电议型 号:T83570产 地:中国大陆
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T8345114,15-Epoxyeicosatrienoic acid;化合物 14,15-Epoxyeicosatrienoic acid14,15-EET;14,15-EET
14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer´s Disease research [1] [2].
价 格:¥电议型 号:T83451产 地:中国大陆
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T832606β,7β-Epoxyasteriscunolide A;化合物 6β,7β-Epoxyasteriscunolide A6β,7β-Epoxyasteriscunolide A
6β,7β-Epoxyasteriscunolide A, a sesquiterpenoid, exhibits cytotoxicity against HL-60 and MOLT-3 leukemia cell lines, demonstrating half maximal inhibitory concentrations (IC50s) ranging from 4.1 to 5.4 μM [1].
价 格:¥电议型 号:T83260产 地:中国大陆
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T82456EPO mimetic peptide-1;化合物 EPO mimetic peptide-1EMP-1;EMP-1
EPO Mimetic Peptide-1 (EMP-1) is a 20 amino acid peptide that promotes cell proliferation, modulates the cell cycle, and stimulates reticulocyte production in vivo [1].
价 格:¥电议型 号:T82456产 地:中国大陆
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T82455Epoetin beta;化合物 Epoetin betaGenetical recombination|||rhEPO|||EPOCH;Genetical recombination|||rhEPO
Epoetin beta (rhEPO), a recombinant erythropoietin, is crucial for sustaining erythropoiesis and is utilized in anemia research [1].
价 格:¥电议型 号:T82455产 地:中国大陆
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T82454Epoetin zeta;化合物 Epoetin zetaEpoetin zeta
Epoetin zeta, a derivative of the endogenous protein erythropoietin, functions as an erythropoiesis-stimulating agent. It is utilized to investigate symptomatic anemia associated with renal disorders, referred to as symptomatic renal anemia [1].
价 格:¥电议型 号:T82454产 地:中国大陆
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T82453Epothilone D1;化合物 Epothilone D1Epothilone D1
Epothilone D1, a naturally derived isolate, exhibits cytotoxic effects on mouse fibroblasts.
价 格:¥电议型 号:T82453产 地:中国大陆
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T82452Epoxy Fluor 7;化合物 Epoxy Fluor 7Epoxy Fluor 7
Epoxy Fluor 7, a fluorescent substrate specific to soluble epoxide hydrolase (sEH), is utilized in the measurement of sEH activity through its hydrolysis-induced fluorescence in both human and mouse enzymes.
价 格:¥电议型 号:T82452产 地:中国大陆
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T81952Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo-;化合物 Lanosta-7,9(11),23,25(27)-tetr
Lanosta-7,9(11),23,25(27)-tetraen-26-oic acid, 23,27-epoxy-3-oxo-, a lanosterane-type compound, can be isolated from Tu-Jin-Pi, the root bark of Pseudolarix kaempferi [1].
价 格:¥电议型 号:T81952产 地:中国大陆
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T81431Pol (476-484), HIV-1 RT Epitope;化合物 Pol (476-484), HIV-1 RT EpitopePol (476-484), HIV-1 RT Epitope
Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A*0201-restricted epitope within HIV-1 reverse transcriptase (RT), spanning Pol residues 476-484. It has been utilized to explore potential mechanisms of HIV-1 escape from cytotoxic T lymphocytes (CTL), with IV9 being the specific epitope processed and presented in HIV-1-infected cell lines.
价 格:¥电议型 号:T81431产 地:中国大陆
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T81430Polyfuroside;化合物 PolyfurosidePolyfuroside
Polyfuroside, a triterpenoid saponin, can be isolated from the defatted rhizome of Jade Bamboo [1].
价 格:¥电议型 号:T81430产 地:中国大陆
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T8014Epoxylinalool;氧化芳樟醇2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran;氧化芳樟醇|||2-(2-Hydroxy-2-Pro
Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) is a naturally occurring monoterpene alcohol widely used in the production of perfumes and flavors.
价 格:¥电议型 号:T8014产 地:中国大陆
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T79926Poly(A) polymerase;化合物 Poly(A) polymerasePoly(A) polymerase
Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3´ end of RNA, a process that involves integrating ATP as AMP. This modification enhances RNA stability and augments mRNA translation efficiency in eukaryotic cells, evidencing the enzyme´s high tailing efficiency [1] [2].
价 格:¥电议型 号:T79926产 地:中国大陆
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T793116a,17a-Epoxy-4-Pregnen-3,20-Dione;16,17-环氧黄体酮16a,17a-Epoxy-4-Pregnen-3,20-Dione
16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progesterone on reproductive organs, the effects of the hormone on cell growth and development, and the effects of the hormone on the immune system.
价 格:¥电议型 号:T7931产 地:中国大陆
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T7893Bepotastine;贝托斯汀Bepotastine free base;Bepotastine free base|||贝托斯汀
Bepotastine (Bepotastine free base) free base is a histamine 1 (H1) receptor antagonis.
价 格:¥电议型 号:T7893产 地:中国大陆
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T78524Polystyrene;化合物 PolystyrenePolystyrene
Polystyrene microplastics (PS-MPs) are a toxic substance that poses risks to aquatic life, specifically causing cardiac harm to zebrafish and inducing male reproductive toxicity in mice [1] [2].
价 格:¥电议型 号:T78524产 地:中国大陆
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T77982Pomalidomide-5-C12-NH2 hydrochloride;化合物 Pomalidomide-5-C12-NH2 hydrochloridePomalidomide-5-C12-NH2
Pomalidomide-5-C12-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be conjugated to a protein-targeting ligand via a linker to create a PROTAC [1].
价 格:¥电议型 号:T77982产 地:中国大陆