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T15976Mal-PEG1-NHS ester
Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It also is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T15976产 地:中国大陆
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T14413Azido-PEG10-alcohol叠氮-十聚乙二醇
Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T14413产 地:中国大陆
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T14408Azido-PEG1-CH2CO2H4-哌啶酮缩乙二醇
Azido-PEG1-CH2CO2H is a PROTAC linker that refers to an alkyl/ether combination. Azido-PEG1-CH2CO2H can be used to synthesize PROTAC BRD4 Degrader-1[1].
价 格:¥电议型 号:T14408产 地:中国大陆
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T14226Amino-PEG11-amine氨基-十二聚乙二醇-氨基
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
价 格:¥电议型 号:T14226产 地:中国大陆
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T14137AG 1295
AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autophosphorylation of the PDGFR. But it can not affects the autophosphorylation of the EGF receptor[1][2][3][4].
价 格:¥电议型 号:T14137产 地:中国大陆
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T13238Tyrphostin AG1433AG1433;SU1433
Tyrphostin AG1433 is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).
价 格:¥电议型 号:T13238产 地:中国大陆
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T13202Trilaciclib hydrochlorideG1T28 hydrochloride
Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).
价 格:¥电议型 号:T13202产 地:中国大陆
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T11345LLerociclib dihydrochlorideG1T38 dihydrochloride
Lerociclib dihydrochloride is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
价 格:¥电议型 号:T11345L产 地:中国大陆
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T11344G150
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
价 格:¥电议型 号:T11344产 地:中国大陆
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T10616BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50s<0.005 μM).
价 格:¥电议型 号:T10616产 地:中国大陆
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T10552Bitopertin R enantiomerBitopertin R enantiomer,RG1678 (R enantiomer),RO4917838 (R enantiomer)
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格:¥电议型 号:T10552产 地:美洲
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T11344G150G150
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
价 格:¥电议型 号:T11344产 地:美洲
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T11345LLerociclib dihydrochlorideLerociclib dihydrochloride,G1T38 dihydrochloride,
Lerociclib dihydrochloride is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3?and CDK4/CyclinD1, respectively.?
价 格:¥电议型 号:T11345L产 地:美洲
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T11347G6PD activator AG1G6PD activator AG1
G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) activator with an EC50 of 3 ?Μ.
价 格:¥电议型 号:T11347产 地:美洲
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T11411GLPG1205GLPG1205
GLPG1205 is potent, selective and orally active GPR84 (a G-protein-coupled receptor) antagonist with a favorable PK/PD profile.?GLPG1205 has anti-inflammatory activity and is used for the treatment of pulmonary fibrosis.?
价 格:¥电议型 号:T11411产 地:美洲
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T11735K-Ras G12C-IN-1K-Ras G12C-IN-1
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
价 格:¥电议型 号:T11735产 地:美洲
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T11736K-Ras G12C-IN-2K-Ras G12C-IN-2
K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.
价 格:¥电议型 号:T11736产 地:美洲
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T11737K-Ras G12C-IN-3K-Ras G12C-IN-3
K-ras G12C inhibitor For more information, please see the following patent. Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.
价 格:¥电议型 号:T11737产 地:美洲
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T13202Trilaciclib hydrochlorideTrilaciclib hydrochloride,G1T28 hydrochloride,
Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively).
价 格:¥电议型 号:T13202产 地:美洲
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T13238Tyrphostin AG1433Tyrphostin AG1433,SU1433,AG1433
Tyrphostin AG1433 (SU1433) is a inhibitor of tyrosine kinases,and also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor(IC50s of 5.0 μM and 9.3 μM, respectively).
价 格:¥电议型 号:T13238产 地:美洲