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T35528LTD52 dihydrochloride
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity.
价 格:¥电议型 号:T35528L产 地:中国大陆
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T23535LXanthine amine congener trihydrochlorideXanthine amine congener trihydrochloride
Xanthine amine congener trihydrochloride is a potent adenosine antagonist that reverses the reduction in urine flow, sodium excretion and heart rate produced by the adenosine agonist, N6-cyclohexyladenosine.
价 格:¥电议型 号:T23535L产 地:中国大陆
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T8048Diphenylamine HydrochlorideDiphenylamine Hydrochloride,N-Phenylaniline,Inhibitor,Diphenylamine,inhib
Diphenylamine Hydrochloride is a natural product that used mainly for its antioxidant properties.
价 格:¥电议型 号:T8048产 地:中国大陆
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T9172Simufilam dihydrochlorideInhibitor,PTI-125,Simufilam,inhibit,PTI 125,PTI125,Simufilam dihydrochlorid
Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer´s disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
价 格:¥电议型 号:T9172产 地:中国大陆
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T8822JNJ-5207852 dihydrochlorideInhibitor,toxicity,JNJ5207852,inhibit,low,JNJ 5207852,sleep,REM,JNJ-52078
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor.
价 格:¥电议型 号:T8822产 地:中国大陆
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T73711-Naphthyl PP1 hydrochloride1 Naphthyl PP1 hydrochloride,Src,1Naphthyl PP1 hydrochloride,1-Naphthyl
1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src
价 格:¥电议型 号:T7371产 地:中国大陆
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TQ0138K145 hydrochlorideK-145,K 145,ERK,K145 hydrochloride,K145,Sphingosine kinase,anti-proliferative,SphK
K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity, with IC50 of 4.3 ?M and Ki of 6.4 ?M. K145 hydrochloride can induce apoptosis and has strong antitumor activity.
价 格:¥电议型 号:TQ0138产 地:中国大陆
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T9681MAK-683 hydrochlorideEED inhibitor,MAK 683 hyrochloride,embryonic ectoderm development,Histone Methy
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED) (patent US20160176882 A1, compound example 2). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.
价 格:¥电议型 号:T9681产 地:中国大陆
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T7555Piperidolate hydrochlorideInhibitor,Piperidolate,inhibit,Muscarinic acetylcholine receptor,Piperidol
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs).
价 格:¥电议型 号:T7555产 地:中国大陆
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TQ0296LN-Nornuciferine hydrochloride(4846-19-9 free base)NNornuciferine hydrochloride(4846199 free base),N
N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).
价 格:¥电议型 号:TQ0296L产 地:中国大陆
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T8442M8-B HydrochlorideM8 B Hydrochloride,M-8-B Hydrochloride,M8B Hydrochloride
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
价 格:¥电议型 号:T8442产 地:中国大陆
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T23325SB 699551 dihydrochlorideSB 699551
SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.
价 格:¥电议型 号:T23325产 地:中国大陆
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T23048N20C hydrochloride
N20C hydrochloride is a non-competitive NMDA receptor open-channel blocker.
价 格:¥电议型 号:T23048产 地:中国大陆
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T22657Laduviglusib trihydrochloride
Laduviglusib trihydrochloride is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α and GSK-3β. Laduviglusib trihydrochloride inhibits human GSK-3β with a Ki of 9.8 nM. Laduviglusib trihydrochloride is an activator of Wnt/β-catenin signaling. Laduviglusib trihydrochloride induces autophagy.
价 格:¥电议型 号:T22657产 地:中国大陆
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T8405Vardenafil hydrochloridePDE-5 inhibitors,Vardenafil,Endogenous Metabolite,diabetes,Zucker diabetic f
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes
价 格:¥电议型 号:T8405产 地:中国大陆
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TN5283L-Cysteine hydrochloride hydrateInhibitor,semi-essential,anorectic,endogenous,1880366,L-Cysteine hyd
L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), taurine and glutathione. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans.
价 格:¥电议型 号:TN5283产 地:中国大陆
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T7556Fadrozole hydrochlorideP-450,(Rac)-FAD286,Aromatase,spontaneous tumour,Fadrozole hydrochloride,Fadro
Fadrozole hydrochloride is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
价 格:¥电议型 号:T7556产 地:中国大陆
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T12510PNU-177864 hydrochloride
PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor. PNU-177864 hydrochloride is structurally consistent with a cationic amphiphilic drug (CAD). PNU-177864 hydrochloride induces phospholipidosis in vivo. PNU-177864 hydrochloride exhibits antischizophrenic activity.
价 格:¥电议型 号:T12510产 地:中国大陆
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TP1236Etelcalcetide hydrochlorideEtelcalcetide hydrochloride,KAI-4169,AMG416,KAI4169,CaSR,KAI 4169,AMG 416
Etelcalcetide hydrochloride is a synthetic peptide as an allosteric modulator of the calcium (Ca)-sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
价 格:¥电议型 号:TP1236产 地:中国大陆
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T0364LDibucaine hydrochlorideinhibit,Na channels,Na+ channels,Cinchocaine,SChE,BSA-gold,Inhibitor,Sodium C
Dibucaine hydrochloride, a long-acting local amide anestheticsis, is usually used for surface anesthesia.
价 格:¥电议型 号:T0364L产 地:中国大陆