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产品数:86101
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T7190ActeinJNK,Akt,Actein,Apoptosis,PKB,Autophagy,Inhibitor,inhibit,Protein kinase B
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein´s ability to pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders, it has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing cal
价 格:¥电议型 号:T7190产 地:中国大陆
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T2454DacinostatLAQ-824,Dacinostat,Histone deacetylases,inhibit,Autophagy,HDAC,Inhibitor,LAQ 824
LAQ824 (Dacinostat) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
价 格:¥电议型 号:T2454产 地:中国大陆
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T63918α-Tocopherol phosphate disodium
α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. alpha-Tocopherol phosphate disodium impedes endothelial progenitor cell apoptosis, enhances endothelial progenitor cell migration under high glucose/low oxygen conditions and promotes angiogenesis. α-Tocopherol phosphate disodium prevents apoptosis, enhances migration of endothelial progenitor cells under high gluc
价 格:¥电议型 号:T63918产 地:中国大陆
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T7864ChlorprophamChlorpropham
Chlorpropham acts as a plant growth regulator and herbicide.
价 格:¥电议型 号:T7864产 地:中国大陆
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T7388GSK805GSK 805,immunity,RAR-related orphan receptor,Inhibitor,GSK805,inhibit,ROR,oral,CNS penetrant,G
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor´s putative ligand binding domain without exerting significant effects on DNA binding
价 格:¥电议型 号:T7388产 地:中国大陆
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T23145PHA 543613PHA 543613 hydrochloride
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer´s disease and schizophrenia.
价 格:¥电议型 号:T23145产 地:中国大陆
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T6468D-glutamineMitophagy,inhibit,Autophagy,D glutamine,Dglutamine,D-Glutamine,Endogenous Metabolite,Mito
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
价 格:¥电议型 号:T6468产 地:中国大陆
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TN1079DeoxyelephantopinAkt,Inhibitor,β-catenin,Deoxyelephantopin,MAPK,Nuclear factor-κB,NF-κB,PI3K,Nuclear
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling
价 格:¥电议型 号:TN1079产 地:中国大陆
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TMS1743SalvigeninSalvigenin,inhibit,Apoptosis,immunomodulatory,ROS Kinase,Autophagy,Inhibitor,neuroprotecti
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.
价 格:¥电议型 号:TMS1743产 地:中国大陆
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T8808LLYN-1604 dihydrochlorideanti-tumor,Unc-51 like kinase,negative,LYN-1604,LYN 1604,cancer,Autophagy,br
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
价 格:¥电议型 号:T8808L产 地:中国大陆
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TP1072ValinomycinNSC-122023,Apoptosis,Bacterial,Autophagy,Inhibitor,inhibit,Valinomycin,Antibiotic,NSC1220
Valinomycin is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.
价 格:¥电议型 号:TP1072产 地:中国大陆
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T9079Apostatin-1Apostatin 1,TRADD,Apostatin-1,Beclin1,RIPK,Autophagy,SH-SY5Y,Receptor-interacting protein
Apostatin-1 is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.
价 格:¥电议型 号:T9079产 地:中国大陆
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T6521GSK 2830371GSK-2830371,Inhibitor,GSK 2830371,Phosphatase,inhibit
GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
价 格:¥电议型 号:T6521产 地:中国大陆
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TQ0212GlucoraphaninReactive Oxygen Species,Glucoraphanin,Inhibitor,inhibit
Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.
价 格:¥电议型 号:TQ0212产 地:中国大陆
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T65979Adenosine 5′-monophosphate disodium salt
价 格:¥电议型 号:T65979产 地:中国大陆
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T7530PD146176inhibit,tau,brain,triple,NSC-168807,PD146176,Autophagy,pathology,amyloidosis,transgenic,reti
PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
价 格:¥电议型 号:T7530产 地:中国大陆
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TN2225Soyasapogenol BApoptosis,Autophagy,Soyasapogenol B,Inhibitor,inhibit
Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
价 格:¥电议型 号:TN2225产 地:中国大陆
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T6677SophocarpineApoptosis,Sophocarpine,Influenza Virus,PI3K,Phosphoinositide 3-kinase,Inhibitor,Autophag
Sophocarpine has anti-cancer, anti-inflammatory, anti-nociceptive, and antivirus activities, it can prevent implant loosening through inhibiting osteoclast formation and bone resorption, thus, it may be a novel therapeutic agent to prevent prosthesis loosening and for osteolytic diseases. Sophocarpine could attenuate ConA-induced liver injury, and the protective effect of Sophocarpine was associated with its inhibition effect of pro-inflammatory cytokines, chemokines, and the IFN-γ/STAT1 signali
价 格:¥电议型 号:T6677产 地:中国大陆
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T6799IITZ-01Phosphoinositide 3-kinase,IITZ 01,IITZ01,Apoptosis,IITZ-01,Autophagy,inhibit,Inhibitor,PI3K
IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)
价 格:¥电议型 号:T6799产 地:中国大陆
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TN13347-Methoxyrosmanol7-Methoxyrosmanol,inhibit,Inhibitor,7Methoxyrosmanol,7 Methoxyrosmanol
7-O-Methylrosmanol can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity.
价 格:¥电议型 号:TN1334产 地:中国大陆