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产品数:86101
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T25310Dersimelagon
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation.
价 格:¥电议型 号:T25310产 地:中国大陆
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T7609ARS-1620inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620
ARS-1620 is a covalent inhibitor of K-RASG12C.
价 格:¥电议型 号:T7609产 地:中国大陆
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T6948Pluripotininhibit,Extracellular signal regulated kinases,Ribosomal S6 Kinase (RSK),SC-1,SC 1,Inhibit
Pluripotin (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.
价 格:¥电议型 号:T6948产 地:中国大陆
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T6482Efaproxiral SodiumRSR-13,RSR13,Reactive Oxygen Species,RSR 13,Efaproxiral Sodium,Inhibitor,inhibit,E
Efaproxiral Sodium , a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
价 格:¥电议型 号:T6482产 地:中国大陆
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TN1557Decursinol angelateProtein kinase C,inhibit,Inhibitor,Decursinol angelate,PKC
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.
价 格:¥电议型 号:TN1557产 地:中国大陆
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T9618HeE1-2TyrHeE12Tyr,Nile,West,SARS-CoV,HeE1 2Tyr,SARS coronavirus,RdRp,HeE1-2Tyr,inhibit,HeE-1-2Tyr,fl
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 ?M) activity in vitro.
价 格:¥电议型 号:T9618产 地:中国大陆
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T9635CedirogantInhibitor,inverse,ROR,Cedirogant,ABBV157,RORγt,RAR-related orphan receptor,psoriasis,inhib
Cedirogant is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for psoriasis study.
价 格:¥电议型 号:T9635产 地:中国大陆
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T9099Disperse Fast Yellow 4KDisperse Fast Yellow 4K
Disperse Fast Yellow 4K is a color additive used in dyes.
价 格:¥电议型 号:T9099产 地:中国大陆
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T9331Bemnifosbuvir hemisulfateInhibitor,antiviral,phosphoramidate,HCV,nucleotide,SARS-CoV,pangenotypic,Be
Bemnifosbuvir hemisulfate is a potent inhibitor of HCV virus replication.
价 格:¥电议型 号:T9331产 地:中国大陆
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T7494TCN238inhibit,TCN-238,mGluR,TCN238,Metabotropic glutamate receptors,Inhibitor
TCN 238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).
价 格:¥电议型 号:T7494产 地:中国大陆
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T9223RO-0335Reverse Transcriptase,RO0335,RO 0335,nonnucleoside,novel,inhibit,diphenylether,potent,HIV-1,R
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.
价 格:¥电议型 号:T9223产 地:中国大陆
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TP1938LRS09 2TFA (1449566-36-2 free base)RS09 2TFA (1449566362 free base),RS09 2TFA (1449566 36 2 free base
RS09 2TFA is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. It acts as an adjuvant in vivo and enhances X-15 specific antibody serum concentrations.
价 格:¥电议型 号:TP1938L产 地:中国大陆
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T9685DS-1971ahypersensitivity,thermal,Sodium Channel,hyperalgesia,Na channels,inhibit,Na+ channels,Inhibi
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
价 格:¥电议型 号:T9685产 地:中国大陆
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TN1648Forsythoside HForsythoside H
Forsythoside H is a nartural product from Forsythia suspense (Thunb.) Vahl.
价 格:¥电议型 号:TN1648产 地:中国大陆
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T6598MPEPMetabotropic glutamate receptors,inhibit,MPEP,mGluR,Inhibitor
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
价 格:¥电议型 号:T6598产 地:中国大陆
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T7058Selisistat S-enantiomerSelisistat Senantiomer,Sirtuin,(S)-Selisistat,Selisistat S enantiomer,inhibit
Selisistat S-enantiomer is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.
价 格:¥电议型 号:T7058产 地:中国大陆
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T8486GW6471Peroxisome proliferator-activated receptors,Inhibitor,GW6471,inhibit,GW-6471,PPAR
GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.
价 格:¥电议型 号:T8486产 地:中国大陆
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TN1065Hirsutineinhibit,Apoptosis,Inhibitor,Hirsutine
Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels.
价 格:¥电议型 号:TN1065产 地:中国大陆
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T7599SunifiramDM 235,Inhibitor,iGluR,Sunifiram,DM235,Ionotropic glutamate receptors,inhibit
Sunifiram is a potent nootropic agent.
价 格:¥电议型 号:T7599产 地:中国大陆
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T7111Tenofovir DisoproxilInhibitor,GS-4331,Reverse Transcriptase,Tenofovir Disoproxil,HIV,GS4331,Human im
Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
价 格:¥电议型 号:T7111产 地:中国大陆