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T68648Diprafenone Free Base;化合物 Diprafenone Free BaseDiprafenone Free Base
Diprafenone Free Base is an antiarrhythmic beta adrenergic antagonist.
价 格:¥电议型 号:T68648产 地:中国大陆
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T68518Diprafenone HCl;化合物 Diprafenone HClDiprafenone HCl
Diprafenone HCl is the salt form of Diprafenone Free Base, an antiarrhythmic beta adrenergic antagonist.
价 格:¥电议型 号:T68518产 地:中国大陆
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T68090Laprafylline;拉普茶碱Laprafylline
Laprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.Laprafylline acts as a competitive serotonergic antagonist at low concentrations, and inhibits constriction induced by hist at high difficulties.
价 格:¥电议型 号:T68090产 地:中国大陆
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T67862B-Raf IN 13;化合物B-Raf IN 13B-Raf IN 13
B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.
价 格:¥电议型 号:T67862产 地:中国大陆
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T6525GW 5074化合物GW5074GW5074|||3-(3,5-二溴-4-羟基苯亚甲基)-5-碘-1,3-二氢吲哚-2-酮|||Raf1 Kinase Inhibitor I
GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.
价 格:¥电议型 号:T6525产 地:中国大陆
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T6487Encorafenib;化合物EncorafenibLGX818;LGX818
Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
价 格:¥电议型 号:T6487产 地:中国大陆
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T64869Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate;化合物 Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)pro
Ethyl 3-oxo-3-(2,3,4,5-tetrafluorophenyl)propanoate is a useful organic compound for research related to life sciences. The catalog number is T64869 and the CAS number is 94695-50-8.
价 格:¥电议型 号:T64869产 地:中国大陆
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T64746Paraffin liquid;化合物 Paraffin liquidParaffin liquid
Paraffin liquid is a useful organic compound for research related to life sciences and the catalog number is T64746.
价 格:¥电议型 号:T64746产 地:中国大陆
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T64697(S)-DIFLUORPHOS;化合物 (S)-5,5’-Bis(diphenylphosphino)-2,2,2’,2’-tetrafluoro-4,4’-bi-1,3-benzodioxole(S
(S)-DIFLUORPHOS has a wide range of applications in life science related research.
价 格:¥电议型 号:T64697产 地:中国大陆
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T64194Belvarafenib TFA;化合物 Belvarafenib TFABelvarafenib TFA
Belvarafenib TFA (HM95573 TFA) is a potent and broadly available rapidly accelerating inhibitor of fibrosarcoma kinase (RAF) that acts on B-RAF (IC50: 56 nM), B-RAFv600E (IC50: 7 nM) and C-RAF (IC50: 5 nM).
价 格:¥电议型 号:T64194产 地:中国大陆
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T64116B-Raf IN 5;化合物 B-Raf IN 5B-Raf IN 5
B-Raf IN 5 is a potent inhibitor of the protein kinase B-Raf (IC50: 2.0 nM). B-Raf IN 5 resists rapid metabolism and does not bind to the secondary target PXR.
价 格:¥电议型 号:T64116产 地:中国大陆
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T64090Regorafenib mesylate;化合物 Regorafenib mesylateRegorafenib mesylate
Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRβ (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM) and Raf-1 (IC50: 2.5 nM). Regorafenib mesylate has potent anti-tumour and anti-angiogenic effects.
价 格:¥电议型 号:T64090产 地:中国大陆
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T63882BRAF V600E/CRAF-IN-2;化合物 BRAF V600E/CRAF-IN-2BRAF V600E/CRAF-IN-2
BRAF V600E/CRAF-IN-2 is a potent inhibitor of BRAFV600E/CRAF with IC50 values of 0.888 and 0.229 μM, respectively.BRAF V600E/CRAF-IN-2 induces cell cycle arrest at G0/G1 phase and apoptosis in HCT-116 colon cancer cells.BRAF V600E/CRAF-IN-2 has shown research potential for cancer disease. CRAF-IN-2 has shown potential for research into cancer disease.
价 格:¥电议型 号:T63882产 地:中国大陆
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T63855B-Raf IN 6;化合物 B-Raf IN 6B-Raf IN 6
B-Raf IN 6 is a potent inhibitor (IC50: 1.7 nM) of the protein kinase B-Raf, which does not bind the secondary target PXR and is resistant to rapid metabolism.B-Raf IN 6 has shown research potential in cancer diseases.
价 格:¥电议型 号:T63855产 地:中国大陆
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T63644Exarafenib;埃拉非尼RAF/KIN_2787;RAF/KIN_2787
Exarafenib (RAF/KIN_2787) is a potent and orally available pan-RAF inhibitor.Exarafenib has antitumor activity and acts by inhibiting downstream MAPK pathway signaling.Exarafenib is used in cancer research.
价 格:¥电议型 号:T63644产 地:中国大陆
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T63448BRAF V600E/CRAF-IN-1;化合物 BRAF V600E/CRAF-IN-1BRAF V600E/CRAF-IN-1
BRAF V600E/CRAF-IN-1 is a potent inhibitor of BRAFV600E/CRAF. BRAF V600E/CRAF-IN-1 acts in the G0/G1 phase of HCT-116 colon cancer cells to arrest the cell cycle and cause apoptosis. BRAF V600E/CRAF-IN-1 shows potential for cancer disease research.
价 格:¥电议型 号:T63448产 地:中国大陆
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T63386Pan-RAF kinase inhibitor 1;化合物 Pan-RAF kinase inhibitor 1Pan-RAF kinase inhibitor 1
Pan-RAF kinase inhibitor 1 is a potent inhibitor of the Pan-RAF kinase pair that inhibits RAF kinase and regulates MAPK signaling, thereby affecting the proliferation of RAS-mutated tumor cells. Pan-RAF kinase inhibitor 1 has shown research potential for the study of cancer diseases.
价 格:¥电议型 号:T63386产 地:中国大陆
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T63365RAF-IN-1;化合物 RAF-IN-1RAF-IN-1
RAF-IN-1 is a potent inhibitor of b/cRAF, acting on cRAF (IC50: 3.8 nM), bRAFwt (IC50: 36 nM), bRAFV600E (IC50: 29.4 nM) and inhibiting A375 and H358 cell lines carrying the bRAFV600E mutation with a GI50 of 3.4 and 2.9 nM.
价 格:¥电议型 号:T63365产 地:中国大陆
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T63333Uplarafenib;化合物UplarafenibB-Raf IN 10;B-Raf IN 10
Uplarafenib (B-Raf IN 10) is a potent BRAF inhibitor with an IC50 in the range of 50-100 nM.B-Raf IN 10 has antitumor activity that may affect cell proliferation and differentiation did not, and can be used to study solid tumors.
价 格:¥电议型 号:T63333产 地:中国大陆
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T63210Everafenib;化合物 EverafenibEverafenib
Everafenib is a potent BRAF inhibitor that crosses the blood-brain barrier and also inhibits the MAPK pathway. Everafenib inhibits the activity of a range of V600EBRAF melanoma cell lines (IC50: 2-10 nM) and is more effective than Dabrafenib and Vemurafenib. Everafenib was effective in extending the number of days of survival in a mouse model of intracranial metastatic melanoma.
价 格:¥电议型 号:T63210产 地:中国大陆