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T4867Erucic acidErucic acid,cis-13-docosenoic acid,13(Z)-Docosenoic Acid
Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid is broken down long-chain acyl-coenzyme A (CoA) dehydrogenase, which is produced in
价 格:¥电议型 号:T4867产 地:美洲
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T4944Nervonic acidNervonic acid,cis-15-Tetracosenoic acid,Selacholeic acid
Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functions and prevent demyelination (Chemical Land21). Resear
价 格:¥电议型 号:T4944产 地:美洲
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T5337IACS-10759IACS-10759,IACS10759,IACS 10759
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
价 格:¥电议型 号:T5337产 地:美洲
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T5675HS-10296 hydrochlorideHS-10296 hydrochloride
HS-10296 hydrochloride is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
价 格:¥电议型 号:T5675产 地:美洲
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T5849JMS-17-2JMS-17-2
JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
价 格:¥电议型 号:T5849产 地:美洲
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T6247NMS-P937NMS-P937,NMS-1286937,
NMS-P937 (NMS1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.
价 格:¥电议型 号:T6247产 地:美洲
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T6311BafetinibBafetinib,NS-187,INNO-406
Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
价 格:¥电议型 号:T6311产 地:美洲
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T8784IGS-1.76;化合物IGS-1.76IGS-1.76
IGS-1.76 exhibits pronounced affinity towards hNCS-1 and effectively modulates the interaction between hNCS-1 and Ric8a. Moreover, IGS-1.76 proficiently inhibits the complex formed by human NCS-1 and Ric8a.
价 格:¥电议型 号:T8784产 地:中国大陆
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T8651CAL-101;化合物CAL-101(S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one|||GS-110
CAL-101 (Idelalisib) is a selective inhibitor of p110δ(IC50 : 2.5 nM; in cell-free assays); shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
价 格:¥电议型 号:T8651产 地:中国大陆
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T8470BMS-1001;化合物BMS-1001BMS-1001
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
价 格:¥电议型 号:T8470产 地:中国大陆
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T83538(R)-1-PeCSO;化合物 (R)-1-PeCSOIsoalliin|||trans-(+)-S-1-Propenyl-L-cysteine sulfoxide;Isoalliin|||trans
(R)-1-PeCSO, also known as trans-(+)-S-1-Propenyl-L-cysteine sulfoxide, constitutes the primary flavor precursor in onions [1].
价 格:¥电议型 号:T83538产 地:中国大陆
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T834152-(trans-1,4-Dihydroxy-cyclohexyl)-5,7-dihydroxy-chromone;化合物 2-(trans-1,4-Dihydroxy-cyclohexyl)-5,7
2-(trans-1,4-Dihydroxy-cyclohexyl)-5,7-dihydroxy-chromone, a flavone derivative isolated from Macrothelypteris torresiana, exhibits cytotoxic properties [1].
价 格:¥电议型 号:T83415产 地:中国大陆
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T833922a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid;化合物 2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic a
2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid (compound 3), a triterpenoid, markedly reduces fibronectin levels by 27.66% at a concentration of 10 μM in HK-2 cells subjected to high-glucose and TGF-b1 induction [1].
价 格:¥电议型 号:T83392产 地:中国大陆
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T833732α,3β,24-Trihydroxyurs-12-en-28-oic acid;化合物 2α,3β,24-Trihydroxyurs-12-en-28-oic acid2,24-Dihydroxyu
2α,3β,24-Trihydroxyurs-12-en-28-oic acid, a natural product, is isolated from Salvia palaestina [1].
价 格:¥电议型 号:T83373产 地:中国大陆
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T82711CKS-17;化合物 CKS-17CKS-17
CKS-17, a synthetic retroviral envelope peptide, embodies conserved amino acid sequences found in the transmembrane envelope proteins of various animal and human retroviruses. This immunomodulatory epitope exerts suppressive effects on a range of immune functions [1] [2] [3].
价 格:¥电议型 号:T82711产 地:中国大陆
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T8241cis-10-Heptadecenoic acid;顺式-10-十七烯酸cis-10-Heptadecenoic acid
cis-10-Heptadecenoic acid is a minor constituent of ruminant fats.
价 格:¥电议型 号:T8241产 地:中国大陆
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T82172Hs-1;化合物 Hs-1Hs-1
Hs-1, an antimicrobial peptide, exhibits 80% protection against the Dengue-2 virus [1].
价 格:¥电议型 号:T82172产 地:中国大陆
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T81936LFS-1107;化合物 LFS-1107LFS-1107
LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].
价 格:¥电议型 号:T81936产 地:中国大陆
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T79451WES-1;化合物 WES-1WES-1
WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines, including leukemia (K-562 and MOLT-4), non-small cell lung cancer (NCI-H460), colon cancer (HCT 116 and HCT-15), and melanoma (LOX IMVI) [1].
价 格:¥电议型 号:T79451产 地:中国大陆
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T78467trans-10-Heptadecenoic acid;化合物 trans-10-Heptadecenoic acidtrans-10-Heptadecenoic acid
Trans-10-heptadecenoic acid, a trans-fatty acid, undergoes polymerization to form polyhydroxy-chain alkanoates via the enzymatic actions of 2,4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the enzyme´s absence, degradation is facilitated by enyl-CoA hydratase II from the multifunctional enzyme (MFE), causing significant intracellular carbon release through both reductase-dependent and direct MFE-dependent pathways [1].
价 格:¥电议型 号:T78467产 地:中国大陆