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T13848SMARCA-BD ligand 1 for ProtacSMARCA BD ligand 1 for Protac,SMARCABD ligand 1 for Protac
SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2
价 格:¥电议型 号:T13848产 地:中国大陆
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T8676FOY 251SARS-CoV,inhibit,proteinase,Threonine proteases,metabolism,Serine endopeptidases,FOY 251,obes
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
价 格:¥电议型 号:T8676产 地:中国大陆
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T6763XevinapantSM 406,SM406,Xevinapant,AT-406,oral,inhibit,Debio 1143,ovarian,IAP,degradation,Smac,AT 406
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
价 格:¥电议型 号:T6763产 地:中国大陆
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T7865DanofloxacinInhibitor,Antibiotic,DNA-gyrase,respiratory,mycoplasma,inhibit,Fluoroquinolone,Danofloxa
Danofloxacin is a fluoroquinolone antibiotic used in veterinary medicine.
价 格:¥电议型 号:T7865产 地:中国大陆
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T6728VUF 101665-HT3A,VUF 10166,VUF10166,VUF-10166,neurotransmission,5-HT3AB,inhibit,5-HT3 receptor ligand
VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.
价 格:¥电议型 号:T6728产 地:中国大陆
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T8962TM5007TM 5007,inhibit,TM5007,PAI-1,Plasminogen activator inhibitor-1,Inhibitor,TM-5007
TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).
价 格:¥电议型 号:T8962产 地:中国大陆
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T9395(1S,4R)-N-Desmethyl Sertraline Hydrochloride(1S,4R) N Desmethyl Sertraline Hydrochloride,(1S,4R)NDes
(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.
价 格:¥电议型 号:T9395产 地:中国大陆
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T7133Anagliptinlipid‐lowering,smooth muscle cell,SK0403,inhibit,DPP-4,Anagliptin,Dipeptidyl Peptidase,DPP
Anagliptin is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T7133产 地:中国大陆
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T6514GlasdegibInhibitor,PF 04449913,Glasdegib,inhibit,Smoothened,Smo,PF04449913
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
价 格:¥电议型 号:T6514产 地:中国大陆
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T9777THP104cTHP-104c,Mitochondrial Metabolism,THP104c,inhibit,Inhibitor
THP104c is an inhibitor of mitochondrial fission.
价 格:¥电议型 号:T9777产 地:中国大陆
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T67851rac Desmethyl Citalopram Hydrochloride
rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.
价 格:¥电议型 号:T67851产 地:中国大陆
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TN1644Flavanomareinantioxidative,PI3K,antihypertensive,Smad,anti-hyperlipidemic,Flavanomarein,6-hydroxydop
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells treated with free fatty acids (FFAs).
价 格:¥电议型 号:TN1644产 地:中国大陆
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T6792BQ-123inhibit,blood,Endothelin Receptor,artery,BQ-123,pressure,muscle,smooth,cells,BQ 123,Inhibitor,
BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
价 格:¥电议型 号:T6792产 地:中国大陆
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T9110Ceapin-A7UPR,Inhibitor,CeapinA7,stress,unfolded protein response,reticulum,Golgi,endoplasmic,Ceapin-
Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings.
价 格:¥电议型 号:T9110产 地:中国大陆
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T6619Desmethyl Erlotinib hydrochlorideDesmethyl Erlotinib hydrochloride,CP 373420,inhibit,CP-373420,Inhib
OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.
价 格:¥电议型 号:T6619产 地:中国大陆
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T9420prifinium bromideMuscarinic acetylcholine receptor,Prifinium,prifinium bromide,Inhibitor,Anti-spasmo
Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.
价 格:¥电议型 号:T9420产 地:中国大陆
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T60043DPTIPextracellular,Inhibitor,exosome,DPTIP,Phospholipase,vesicles,inhibit,N-SMase
DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.
价 格:¥电议型 号:T60043产 地:中国大陆
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T35529hSMG-1 inhibitor 11ehSMG 1 inhibitor 11e,hSMG1 inhibitor 11e
hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.
价 格:¥电议型 号:T35529产 地:中国大陆
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T11961MBM-55SMBM 55S,MBM55S
MBM-55S is an effective inhibitor of Nek2 with an IC50 of 1 nM. MBM-55S indecus cell cycle arrest and apoptosis thereby inhibiting the proliferation of cancer cells. MBM-55S shows antitumor activities.
价 格:¥电议型 号:T11961产 地:中国大陆
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T15117Didesmethyl cariprazineDidesmethyl cariprazine
Cariprazine is an antipsychotic drug candidate. It shows high affinity for the D3 and D2 receptors, and moderate affinity for the 5-HT1A receptor. Didesmethyl cariprazine is a metabolite of Cariprazine and acts as the predominant circulating active moiety.
价 格:¥电议型 号:T15117产 地:中国大陆