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T6219Azilsartan Medoxomil;阿齐沙坦酯TAK-491;TAK-491|||阿齐沙坦酯
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
价 格:¥电议型 号:T6219产 地:中国大陆
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T61518TAK-653;化合物TAK-653TAK-653
TAK-653, a selective positive allosteric modulator (PAM) of AMPA receptors exhibiting minimal agonistic activity, elicits an antidepressant-like response while maintaining a favorable safety profile in rat models.
价 格:¥电议型 号:T61518产 地:中国大陆
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T6124Mubritinib;木利替尼TAK-165;木利替尼|||TAK-165
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
价 格:¥电议型 号:T6124产 地:中国大陆
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T6051Orteronel化合物(S)-OrteronelTAK-700|||(S)-Orteronel
Orteronel ((S)-Orteronel)(TAK-700) was selected as a candidate for clinical evaluation. orteronel (TAK-700) is currently in phase III clinical trials for the treatment of castration-resistant prostate cancer.
价 格:¥电议型 号:T6051产 地:中国大陆
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T6050TAK-700;化合物(S/R)-Orteronel(S/R)-Orteronel|||Orteronel;(S/R)-Orteronel|||Orteronel
TAK-700 (Orteronel) (Orteronel) is a potent and highly selective human 17, 20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.
价 格:¥电议型 号:T6050产 地:中国大陆
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T6039TAK-285;化合物TAK-285TAK285|||TAK 285;TAK285|||TAK 285
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
价 格:¥电议型 号:T6039产 地:中国大陆
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T4264Takinib;化合物TakinibEDHS-206;EDHS-206
Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).
价 格:¥电议型 号:T4264产 地:中国大陆
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T4209TAK-659 hydrochloride;化合物TAK-659 hydrochlorideTAK-659;TAK-659
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
价 格:¥电议型 号:T4209产 地:中国大陆
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T40577TAK1-IN-3;TAK1 抑制剂3TAK1-IN-3;TAK1-IN-3
TAK1-IN-3 is a novel ATP-competitive TAK1 inhibitor for the study of cancer.
价 格:¥电议型 号:T40577产 地:中国大陆
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T39816Ceftaroline fosamil inner salt;Ceftaroline fosamil inner saltTAK-599 free acid|||PPI0903freeacid;TAK
Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection.
价 格:¥电议型 号:T39816产 地:中国大陆
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T39553TAK-960 monohydrochloride;TAK-960 monohydrochlorideTAK-960 monohydrochloride
TAK-960 monohydrochloride is an orally available compound that selectively inhibits polo-like kinase 1 (PLK1) with an IC 50 of 0.8 nM. It also demonstrates inhibitory activity against PLK2 (IC 50 of 16.9 nM) and PLK3 (IC 50 of 50.2 nM). Moreover, TAK-960 monohydrochloride effectively suppresses the proliferation of various cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.
价 格:¥电议型 号:T39553产 地:中国大陆
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T39252TAK-418;化合物TAK-418TAK-418
TAK-418 is a selective and orally active inhibitor of LSD1/KDM1A enzyme with an IC50 of 2.9 nM. TAK-418 unlocks abnormal epigenetic mechanisms and improves autism symptoms in models of neurodevelopmental disorders.
价 格:¥电议型 号:T39252产 地:中国大陆
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T38895Zanapezil free baseZanapezil free baseTAK-147 free base|||Zanapezil free base
Zanapezil (TAK-147) is a powerful and selective inhibitor of acetylcholine esterase (AChE). It demonstrates significant and reversible inhibition of AChE activity in rat cerebral cortex homogenates (IC50 = 51.2 nM). Furthermore, Zanapezil exhibits moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. This compound holds promise for the investigation of the initial stages of Alzheimer´s disease (AD).
价 格:¥电议型 号:T38895产 地:中国大陆
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T38863Luvadaxistat;化合物 LuvadaxistatTAK-831|||NBI 1065844;TAK-831|||NBI 1065844
Luvadaxistat (TAK-831) is an orally active, potent and highly selective inhibitor of D-amino acid oxidase (DAAO) with an IC50 value of 14 nM for the oxidative deamination of D-serine.Luvadaxistat is used in the study of schizophrenia and cognitive disorders.
价 格:¥电议型 号:T38863产 地:中国大陆
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T38754Trazpiroben;化合物 TrazpirobenTAK-906;TAK-906
Trazpiroben (TAK-906) is a selective dopamine D2/D3 receptor antagonist used in the study of gastroparesis.
价 格:¥电议型 号:T38754产 地:中国大陆
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T37790TAK-700 salt;TAK-700 saltTAK700 (salt)|||TAK 700 (salt)|||TAK-700 salt;TAK700 (salt)|||TAK 700 (salt
TAK-700 salt is a potent and highly selective inhibitor of human 17,20-lyase with an IC50 of 38 nM and is over 1000-fold more selective than other CYPs such as 11-hydroxylase and CYP3A4.
价 格:¥电议型 号:T37790产 地:中国大陆
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T36782TAK1-IN-2;TAK1-IN-2TAK1-IN-2;TAK1-IN-2
TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50> of 2 nM[1].
价 格:¥电议型 号:T36782产 地:中国大陆
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T3630Relugolix;瑞卢戈利RVT-601|||TAK-385;RVT-601|||瑞卢戈利|||TAK-385
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the anterior pituitary gland, which both prevents GnRH binding to the GnRH receptor and inhibits the secretion and release of both luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prev
价 格:¥电议型 号:T3630产 地:中国大陆
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T3538Sufugolix;化合物SufugolixTAK-013;TAK-013
Sufugolix (TAK-013) is a potent and orally available luteinizing hormone-releasing hormone LHRH receptor.
价 格:¥电议型 号:T3538产 地:中国大陆